-
1
-
-
0027880281
-
Cell-cycle controls: Potential targets for chemical carcinogens
-
Afshari CA, Barrett JC (1993). Cell-cycle controls: Potential targets for chemical carcinogens. Environ Hlth Perspect 101:9-14.
-
(1993)
Environ Hlth Perspect
, vol.101
, pp. 9-14
-
-
Afshari, C.A.1
Barrett, J.C.2
-
2
-
-
0025049435
-
Genotoxicitiy of inhibitors of DNA topoisomerase I (camptothecin) and II (m-amsa) in vivo and in vitro
-
Backer LC, Allen JW, Harrington-Brock K, Campbell JA, DeMarini DM, Doerr CL, Howard DR, Kligerman AD, Moore MM (1990): Genotoxicitiy of inhibitors of DNA topoisomerase I (camptothecin) and II (m-amsa) in vivo and in vitro. Mutagenesis 5:541-547.
-
(1990)
Mutagenesis
, vol.5
, pp. 541-547
-
-
Backer, L.C.1
Allen, J.W.2
Harrington-Brock, K.3
Campbell, J.A.4
DeMarini, D.M.5
Doerr, C.L.6
Howard, D.R.7
Kligerman, A.D.8
Moore, M.M.9
-
3
-
-
0027523461
-
Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced bcl-2 oncoprotein production
-
Baffy G, Miyashita T, Williamson JR, Reed JC (1993): Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced bcl-2 oncoprotein production. J Biol Chem 268:6511-6519.
-
(1993)
J Biol Chem
, vol.268
, pp. 6511-6519
-
-
Baffy, G.1
Miyashita, T.2
Williamson, J.R.3
Reed, J.C.4
-
4
-
-
0026731894
-
Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents
-
Collins MKL, Marvel J, Malde P, Lopes-Rivas A (1992): Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents. J Exp Med 176:1043-1051.
-
(1992)
J Exp Med
, vol.176
, pp. 1043-1051
-
-
Collins, M.K.L.1
Marvel, J.2
Malde, P.3
Lopes-Rivas, A.4
-
5
-
-
0020028066
-
Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line
-
Collins S, Groudine M (1982): Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line. Nature 298:679-681.
-
(1982)
Nature
, vol.298
, pp. 679-681
-
-
Collins, S.1
Groudine, M.2
-
6
-
-
0021187090
-
Assay for gene mutation in a human lymphoblast line. AHH-1, competent for xenobiotic metabolism
-
Crespi CL, Thilly WG (1984) Assay for gene mutation in a human lymphoblast line. AHH-1, competent for xenobiotic metabolism. Mutat Res 128:221-230.
-
(1984)
Mutat Res
, vol.128
, pp. 221-230
-
-
Crespi, C.L.1
Thilly, W.G.2
-
7
-
-
0026492817
-
Features of apoptotic cells measured by flow cytometry
-
Darzynkiewicz Z, Bruno S, del Bino G, Gorczyca W, Hotz MA, Lassota P, Traganos F (1992): Features of apoptotic cells measured by flow cytometry Cytometry 13:795-808.
-
(1992)
Cytometry
, vol.13
, pp. 795-808
-
-
Darzynkiewicz, Z.1
Bruno, S.2
Del Bino, G.3
Gorczyca, W.4
Hotz, M.A.5
Lassota, P.6
Traganos, F.7
-
8
-
-
0018184404
-
Cell-cycle specific chromosome damage following treatment of cultured Chinese hamster cells with 4′[(9-acridmyl)-amino]methanesulphon-in-aniside HCl
-
Deaven LL, Oka MS, Tobey RA (1978) Cell-cycle specific chromosome damage following treatment of cultured Chinese hamster cells with 4′[(9-acridmyl)-amino]methanesulphon-in-aniside HCl. J Nat Cancer Inst 60:115-161.
-
(1978)
J Nat Cancer Inst
, vol.60
, pp. 115-161
-
-
Deaven, L.L.1
Oka, M.S.2
Tobey, R.A.3
-
9
-
-
0025877991
-
Camptothecin, teniposide, or 4′-(9-acridinylamino)-3-methanesulfon-m-aniside, but not mitoxantrone or doxorubicin, induces degradation of nuclear DNA in the S phase of HL-60 cells
-
del Bino G, Darzynkiewicz Z (1991): Camptothecin, teniposide, or 4′-(9-acridinylamino)-3-methanesulfon-m-aniside, but not mitoxantrone or doxorubicin, induces degradation of nuclear DNA in the S phase of HL-60 cells. Cancer Res 51:1165-1169.
-
(1991)
Cancer Res
, vol.51
, pp. 1165-1169
-
-
Del Bino, G.1
Darzynkiewicz, Z.2
-
10
-
-
0025916423
-
The concentration-dependent diversity of effects of topoisomerase-I and -II inhibitors on the cell cycle of HL60 cells
-
del Bino G, Skierski JS, Darzynkiewicz Z (1991): The concentration-dependent diversity of effects of topoisomerase-I and -II inhibitors on the cell cycle of HL60 cells. Exp Cell Res 195:485-491.
-
(1991)
Exp Cell Res
, vol.195
, pp. 485-491
-
-
Del Bino, G.1
Skierski, J.S.2
Darzynkiewicz, Z.3
-
11
-
-
0023403294
-
Mutagenicity of m-amsa and o-amsa in mammalian cells due to clastogenic mechanism. Possible role of topoisomerase
-
DeMarini D, Doerr CL, Meyer MK, Brock KH, Hozier J, Moore MM (1987): Mutagenicity of m-amsa and o-amsa in mammalian cells due to clastogenic mechanism. Possible role of topoisomerase. Mutagenesis 2:349-355.
-
(1987)
Mutagenesis
, vol.2
, pp. 349-355
-
-
DeMarini, D.1
Doerr, C.L.2
Meyer, M.K.3
Brock, K.H.4
Hozier, J.5
Moore, M.M.6
-
12
-
-
0024574046
-
Micronucleus, chromosome aberration, and small-colony TK mutant analysis to quantitate chromosomal damage in L5178Y mouse lymphoma cells
-
Doerr CL, Harrington-Brock K, Moore MM (1989): Micronucleus, chromosome aberration, and small-colony TK mutant analysis to quantitate chromosomal damage in L5178Y mouse lymphoma cells. Mutat Res 222:191-203.
-
(1989)
Mutat Res
, vol.222
, pp. 191-203
-
-
Doerr, C.L.1
Harrington-Brock, K.2
Moore, M.M.3
-
13
-
-
0025033793
-
Cell cycle control in eukaryotes: Molecular mechanisms of cdc2 activation
-
Draetta G (1990): Cell cycle control in eukaryotes: Molecular mechanisms of cdc2 activation. Trend Biochem Sci 15:378-383.
-
(1990)
Trend Biochem Sci
, vol.15
, pp. 378-383
-
-
Draetta, G.1
-
14
-
-
0027287255
-
Multiple pathways to apoptosis
-
Evans VG (1993): Multiple pathways to apoptosis. Cell Biol Int 17:461-476.
-
(1993)
Cell Biol Int
, vol.17
, pp. 461-476
-
-
Evans, V.G.1
-
15
-
-
0025052143
-
Long-term inhibition of DNA synthesis and the persistance of trapped topoisomerase-II complexes in determining the toxicity of the antitumor intercalators m-AMSA and mitoxantrone
-
Fox ME, Smith PJ (1990): Long-term inhibition of DNA synthesis and the persistance of trapped topoisomerase-II complexes in determining the toxicity of the antitumor intercalators m-AMSA and mitoxantrone. Cancer Res 50:5813-5818.
-
(1990)
Cancer Res
, vol.50
, pp. 5813-5818
-
-
Fox, M.E.1
Smith, P.J.2
-
16
-
-
0027269557
-
Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
-
Gorczyca W, Gong J, Darzynkiewicz Z (1993a): Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res 53:1945-1951.
-
(1993)
Cancer Res
, vol.53
, pp. 1945-1951
-
-
Gorczyca, W.1
Gong, J.2
Darzynkiewicz, Z.3
-
17
-
-
0027261147
-
The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents
-
Gorczyca W, Gong J, Ardelt B, Traganos F, Darzynkiewicz Z (1993b): The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res 53:3186-3192.
-
(1993)
Cancer Res
, vol.53
, pp. 3186-3192
-
-
Gorczyca, W.1
Gong, J.2
Ardelt, B.3
Traganos, F.4
Darzynkiewicz, Z.5
-
18
-
-
0027411984
-
Apoptosis of S-phase HL-60 cells induced by topoisomerase inhibitors: Detection of DNA strand breaks by flow cytometry using the in situ nick translation assay
-
Gorczyca W, Melamed MR, Darzynkiewicz Z (1993c): Apoptosis of S-phase HL-60 cells induced by topoisomerase inhibitors: Detection of DNA strand breaks by flow cytometry using the in situ nick translation assay. Tox Lett 67:249-258
-
(1993)
Tox Lett
, vol.67
, pp. 249-258
-
-
Gorczyca, W.1
Melamed, M.R.2
Darzynkiewicz, Z.3
-
19
-
-
15844410035
-
Topoisomerase-II as a target of antitumor agents
-
Hancock R, Charron M, Lambert H, Lemieux M, Pankov R, Pepin N (1990): Topoisomerase-II as a target of antitumor agents. Pharm Therap Suppl. 119-135.
-
(1990)
Pharm Therap
, Issue.SUPPL.
, pp. 119-135
-
-
Hancock, R.1
Charron, M.2
Lambert, H.3
Lemieux, M.4
Pankov, R.5
Pepin, N.6
-
20
-
-
0024420685
-
Arrest of replication forks by drug-stabilized topoisomerase-I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
-
Hsiang Y-H, Lihou MG, Liu LF (1989): Arrest of replication forks by drug-stabilized topoisomerase-I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res 49:5077-5082
-
(1989)
Cancer Res
, vol.49
, pp. 5077-5082
-
-
Hsiang, Y.-H.1
Lihou, M.G.2
Liu, L.F.3
-
21
-
-
0028275077
-
Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the G1 and S phases of the cell cycle without growth arrest or stabilization of wild-type p53
-
Kelley LL, Green WF, Hicks GG, Bondurant M, Koury J, Ruley HE (1994): Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the G1 and S phases of the cell cycle without growth arrest or stabilization of wild-type p53. Mol Cell Biol 14:4183-4192.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4183-4192
-
-
Kelley, L.L.1
Green, W.F.2
Hicks, G.G.3
Bondurant, M.4
Koury, J.5
Ruley, H.E.6
-
22
-
-
0025124583
-
Disposition of amsacrine and its analogue 9-(2-methoxy-4-[(methylsulfonyl)-amino]phenyl)amino-N,5-dimethyl-4- acridinecarboxamide (Cl-921) in plasma, liver and Lewis lung tumors in mice
-
Kestall P, Paxton JW, Evans PC, Young D, Jurlina JL, Robertson IGC, Baguley BC (1990): Disposition of amsacrine and its analogue 9-([2-methoxy-4-[(methylsulfonyl)-amino]phenyl)amino)-N,5-dimethyl-4- acridinecarboxamide (Cl-921) in plasma, liver and Lewis lung tumors in mice. Cancer Res 50:503-508.
-
(1990)
Cancer Res
, vol.50
, pp. 503-508
-
-
Kestall, P.1
Paxton, J.W.2
Evans, P.C.3
Young, D.4
Jurlina, J.L.5
Igc, R.6
Baguley, B.C.7
-
23
-
-
0021125427
-
In vivo and in vitro cytogenetic effects of the anti-tumor agent amsacrine (amsa)
-
Larripa I, Mudry de Pargament M, Labal de Vinuesa M, Demattei A, Brieux de Salum S (1984): In vivo and in vitro cytogenetic effects of the anti-tumor agent amsacrine (amsa). Mutat Res 138:87-91.
-
(1984)
Mutat Res
, vol.138
, pp. 87-91
-
-
Larripa, I.1
Mudry De Pargament, M.2
Labal De Vinuesa, M.3
Demattei, A.4
Brieux De Salum, S.5
-
24
-
-
0024316466
-
DNA topoisomerase poisons as antitumor drugs
-
Liu LF (1989): DNA topoisomerase poisons as antitumor drugs. Annu Rev Biochem 58:351-375.
-
(1989)
Annu Rev Biochem
, vol.58
, pp. 351-375
-
-
Liu, L.F.1
-
25
-
-
0025196215
-
cdc2 kinase activity by etopside or irradiation as a mechanism of G2 arrest in Chinese hamster ovary cells
-
cdc2 kinase activity by etopside or irradiation as a mechanism of G2 arrest in Chinese hamster ovary cells. Cancer Res 50:3761-3766.
-
(1990)
Cancer Res
, vol.50
, pp. 3761-3766
-
-
Lock, R.B.1
Ross, W.E.2
-
26
-
-
0025196216
-
cdc2 kinase in etopside-induced cell death of Chinese hamster ovary cells
-
cdc2 kinase in etopside-induced cell death of Chinese hamster ovary cells. Cancer Res 50:3767-3771.
-
(1990)
Cancer Res
, vol.50
, pp. 3767-3771
-
-
Lock, R.B.1
Ross, W.E.2
-
27
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe SW, Schmitt EM, Smith AW, Osborne BA, Jacks T (1993): p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362:847-848.
-
(1993)
Nature
, vol.362
, pp. 847-848
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, A.W.3
Osborne, B.A.4
Jacks, T.5
-
28
-
-
0021778326
-
The mechanism of action of mAMSA
-
Marshall B, Ralph RK (1985): The mechanism of action of mAMSA. Adv Cancer Res 44.267-293.
-
(1985)
Adv Cancer Res
, vol.44
, pp. 267-293
-
-
Marshall, B.1
Ralph, R.K.2
-
29
-
-
0024390591
-
Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis
-
Morla AO, Draetta G, Beach D, Wang JYJ (1989): Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis. Cell 58:193-203.
-
(1989)
Cell
, vol.58
, pp. 193-203
-
-
Morla, A.O.1
Draetta, G.2
Beach, D.3
Wang, J.Y.J.4
-
30
-
-
0028216951
-
The role of programmed cell death in the toxicity of mutagens, ethyl methanesulfonate and N-ethyl-N′-nitrosourea, in AHH-1 human lymphoblastoid cells
-
Morris SM, McGarrity LJ, Domon OE, Chen JJ, Hinson WG, Bucci TJ, Warbritton AR, Casciano DA (1994): The role of programmed cell death in the toxicity of mutagens, ethyl methanesulfonate and N-ethyl-N′-nitrosourea, in AHH-1 human lymphoblastoid cells. Mutat Res 306:19-34.
-
(1994)
Mutat Res
, vol.306
, pp. 19-34
-
-
Morris, S.M.1
McGarrity, L.J.2
Domon, O.E.3
Chen, J.J.4
Hinson, W.G.5
Bucci, T.J.6
Warbritton, A.R.7
Casciano, D.A.8
-
31
-
-
0029001131
-
Programmed cell death and mutation induction in AHH-1 human lymphoblastoid cells exposed to m-amsa
-
Morris SM, Domon OE, McGarrity LJ, Chen JJ, Casciano DA (1995): Programmed cell death and mutation induction in AHH-1 human lymphoblastoid cells exposed to m-amsa. Mutat Res 329:79-96.
-
(1995)
Mutat Res
, vol.329
, pp. 79-96
-
-
Morris, S.M.1
Domon, O.E.2
McGarrity, L.J.3
Chen, J.J.4
Casciano, D.A.5
-
32
-
-
0021792433
-
Correlations between intercalator-induced DNA strand breaks and sister-chromatid exchanges, mutations and cytotoxicity in Chinese hamster cells
-
Pommier Y, Zwelling LA, Shan CK, Whang-Peng J, Bradley MO (1985): Correlations between intercalator-induced DNA strand breaks and sister-chromatid exchanges, mutations and cytotoxicity in Chinese hamster cells. Cancer Res 45:3143-3149.
-
(1985)
Cancer Res
, vol.45
, pp. 3143-3149
-
-
Pommier, Y.1
Zwelling, L.A.2
Shan, C.K.3
Whang-Peng, J.4
Bradley, M.O.5
-
33
-
-
0026499311
-
Cell cycle effects of the DNA topoisomerase inhibitors camptothecin and m-AMSA in lymphoblastoid cell lines from patients with Fanconi anemia
-
Pool M, Epe B, Hoehn H (1992): Cell cycle effects of the DNA topoisomerase inhibitors camptothecin and m-AMSA in lymphoblastoid cell lines from patients with Fanconi anemia. Mutat Res 270:185-189.
-
(1992)
Mutat Res
, vol.270
, pp. 185-189
-
-
Pool, M.1
Epe, B.2
Hoehn, H.3
-
34
-
-
0028224017
-
Radiation response of mouse lymphoid and myeloid cell lines. Part I. Sensitivity to killing by ionizing radiation, rate of loss of viability and cell type of origin
-
Radford IR (1994): Radiation response of mouse lymphoid and myeloid cell lines. Part I. Sensitivity to killing by ionizing radiation, rate of loss of viability and cell type of origin. Int J Radiat Biol 65:203-215.
-
(1994)
Int J Radiat Biol
, vol.65
, pp. 203-215
-
-
Radford, I.R.1
-
35
-
-
0028181452
-
Radiation response of mouse lymphoid and myeloid cell lines. Part III. Different signals can lead to apoptosis and may influence sensitivity to killing by DNA double-strand breakage
-
Radford IR, Murphy TK (1994): Radiation response of mouse lymphoid and myeloid cell lines. Part III. Different signals can lead to apoptosis and may influence sensitivity to killing by DNA double-strand breakage. Int J Radiat Biol 65:229-239.
-
(1994)
Int J Radiat Biol
, vol.65
, pp. 229-239
-
-
Radford, I.R.1
Murphy, T.K.2
-
36
-
-
0028220486
-
Radiation response of mouse lymphoid and myeloid cell lines. Part II. Apoptotic death is shown by all lines examined
-
Radford IR, Murphy TK, Radley JM, Ellis SL (1994): Radiation response of mouse lymphoid and myeloid cell lines. Part II. Apoptotic death is shown by all lines examined. Int J Radiat Biol 65:217-227.
-
(1994)
Int J Radiat Biol
, vol.65
, pp. 217-227
-
-
Radford, I.R.1
Murphy, T.K.2
Radley, J.M.3
Ellis, S.L.4
-
39
-
-
0028238034
-
Analysis of mitotic cell death caused by radiation in mouse leukemia L5178 cells: Apoptosis is the ultimate form of cell death following mitotic failure
-
Tauchi H, Sawada S (1994): Analysis of mitotic cell death caused by radiation in mouse leukemia L5178 cells: Apoptosis is the ultimate form of cell death following mitotic failure. Int J Radiat Biol 65:449-455.
-
(1994)
Int J Radiat Biol
, vol.65
, pp. 449-455
-
-
Tauchi, H.1
Sawada, S.2
-
40
-
-
0025890303
-
Topoisomerase-II-reactive chemotherapemic drugs induce apoptosis in thymocytes
-
Walker PR, Smith C, Youdale T, Leblanc J, Whitfield JF, Sikorska M (1991): Topoisomerase-II-reactive chemotherapemic drugs induce apoptosis in thymocytes. Cancer Res 1078-1085.
-
(1991)
Cancer Res
, pp. 1078-1085
-
-
Walker, P.R.1
Smith, C.2
Youdale, T.3
Leblanc, J.4
Whitfield, J.F.5
Sikorska, M.6
-
41
-
-
0027587793
-
Cell cycle checkpoints, genetic instability and cancer
-
Weinert T, Lydall D (1993): Cell cycle checkpoints, genetic instability and cancer. Semin Cancer Biol 4:129-140.
-
(1993)
Semin Cancer Biol
, vol.4
, pp. 129-140
-
-
Weinert, T.1
Lydall, D.2
-
42
-
-
0001606206
-
Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells
-
Wolf D, Rotter V (1984): Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells. Proc Natl Acad Sci USA 82:790-794.
-
(1984)
Proc Natl Acad Sci USA
, vol.82
, pp. 790-794
-
-
Wolf, D.1
Rotter, V.2
-
43
-
-
0026670335
-
Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: An overview
-
Wyllie AH (1992): Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: An overview Cancer Metast Rev 11:95-103.
-
(1992)
Cancer Metast Rev
, vol.11
, pp. 95-103
-
-
Wyllie, A.H.1
-
44
-
-
0019867969
-
Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4′-9-acridinylamino-methanesulfon-m-anisidide and adriamycin
-
Zwelling LA, Michaels S, Erickson LR, Ungerleider RS, Nichols M, Kohn KW (1981): Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4′-(9-acridinylamino-methanesulfon-m-anisidide and adriamycin. Biochemistry 20:6553-6563
-
(1981)
Biochemistry
, vol.20
, pp. 6553-6563
-
-
Zwelling, L.A.1
Michaels, S.2
Erickson, L.R.3
Ungerleider, R.S.4
Nichols, M.5
Kohn, K.W.6
-
45
-
-
0025947456
-
Polyploidy induction as a consequence of topoisomerase inhibition. A flow cytometric assessment
-
Zucker ZM, Adams DJ, Bair KW, Elstein KH (1991): Polyploidy induction as a consequence of topoisomerase inhibition. A flow cytometric assessment. Biochem Pharmacol 42:2199-2208.
-
(1991)
Biochem Pharmacol
, vol.42
, pp. 2199-2208
-
-
Zucker, Z.M.1
Adams, D.J.2
Bair, K.W.3
Elstein, K.H.4
|