Expression of hepatocyte growth factor and c-met mRNAs during rat chemically induced hepatocarcinogenesis

Carcinogenesis

Volumn 17, Issue 1, 1996, Pages 19-24

  Imai, Toshio ^a,c   Masui, Tsuneo ^a   Nakanishi, Hayao ^a   Inada, Ken Ichi ^a   Kobayashi, Kiyoshi ^a   Nakamura, Toshikazu ^b   Tatematsu, Masae ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c EISAI CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; DIETHYLNITROSAMINE; GLUTATHIONE TRANSFERASE; MESSENGER RNA; MITOGENIC AGENT; N (2 FLUORENYL)ACETAMIDE; SCATTER FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER NODULE; MALE; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTO ONCOGENE; RAT; RNA TRANSCRIPTION;

2-ACETYLAMINOFLUORENE; ANIMALS; DIETHYLNITROSAMINE; GLUTATHIONE TRANSFERASE; HEPATECTOMY; HEPATOCYTE GROWTH FACTOR; LIVER NEOPLASMS, EXPERIMENTAL; MALE; PRECANCEROUS CONDITIONS; PROTO-ONCOGENE PROTEINS C-MET; RATS; RATS, INBRED F344; RECEPTOR PROTEIN-TYROSINE KINASES; RNA, MESSENGER;

EID: 0029939842     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.1.19     Document Type: Article

References (37)

1. Farber,E. and Sarma,D.S. (1987) Hepatocarcinogenesis: a dynamic cellular perspective. Lab. Invest., 56, 4-22.
2. Kaufmann,W.K., Zhang,Y. and Kaufman,D.G. (1992) Association between expression of transforming growth factor-alpha and progression of hepatocellular foci to neoplasms. Carcinogenesis, 13, 1481-1483.
3. Tanno,S. and Ogawa,K. (1994) Abundant TGFα precursor and EGF receptor expression as a possible mechanism for the preferential growth of carcinogen-induced preneoplastic and neoplastic hepatocytes in rats. Carcinogenesis, 15, 1689-1694.
4. Miller,R.T., Cattley,R.C., Marsman,D.S., Lyght,O. and Popp,J.A. (1995) TGFα is differentially expressed in liver foci induced by diethylnitrosamine initiation and peroxisome proliferator promotion. Carcinogenesis, 16, 77-82.
5. Nakamura,T., Nawa,K. and Ichihara,A. (1984) Partial purification and characterization of hepatocyte growth factor from serum of hepatecomized rats. Biochem. Biophys. Res. Commun., 122, 1450-1459.
6. Thaler,F.J. and Michalopoulos,G.K. (1985) Hepatopoietin A: partial characterization and trypsin activation of a hepatocyte growth factor. Cancer Res., 45, 2545-2549.
7. Russell,W.E., McGowan,J.A. and Bucher,N.L.R. (1984) Partial characterization of a hepatocyte growth factor from rat platelets. J. Cell. Physiol., 119, 183-192.
8. Kinoshita,T., Tashiro,K. and Nakamura,T. (1989) Marked increase of HGF mRNA in non-parenchymal liver cells of rats treated with hepatotoxins. Biochem. Biophys. Res. Commun., 165, 1229-1234.
9. Noji,S., Tashiro,K., Koyama,E., Nohno,T., Ohyama,K., Taniguchi,S. and Nakamura,T. (1990) Expression of hepatocyte growth factor gene in endothelial and Kupffer cells of damaged rat livens, as revealed by in situ hybridization. Biochem. Biophys. Res. Commun., 173, 42-47.
10. Bottaro,D.P., Rubin,J.S., Faletto,D.L., Chan,A.M.-L., Kmiecik,T.E., Vande Woude,G.F. and Aaronson,S.A. (1991) Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science, 251, 802-804.
11. Naldini,L., Vigna,E., Narsimhan,R.P., Gaudino,G., Zarnegar,R. Michalopoulos,G.K. and Comoglio,P.M. (1991) Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET. Oncogene, 6, 501-504.
12. Tashiro,K., Hagiya,M., Nishizawa,T., Seki,T., Shimonishi,M. Shimizu,S. and Nakamura,T. (1990) Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues. Proc. Natl Acad. Sci. USA, 87, 3200-3204.
13. Chan,A.M.-L. et al. (1988) Characterization of the mouse met protooncogene, Oncogene, 2, 593-599.
14. Kinoshita,T., Hirao,S., Matsumoto,K. and Nakamura,T. (1991) Possible endocrine control by hepatocyte growth factor of liver regeneration after partial hepatectomy. Biochem. Biophys. Res. Commun., 177, 330-335.
15. Zarnegar,R., DeFrances,M.C., Kost,D.P. Lindroos,P. and Michalopoulos, G.K. (1991) Expression of hepatocyte growth factor mRXA in regenerating rat liver after partial hepatectomy. Biochem. Biophys. Res. Commun., 177, 559-565.
16. Ito,T., Hayashi,N., Horimoto,M., Sasaki,Y., Tanaka,Y., Kaneko,A., Fusamoto,H. and Kamada,T. (1993) Expression of the c-met/hepatocyte growth factor receptor gene during rat liver regeneration induced by carbon tetrachloride. Biochem. Biophys. Res. Commun., 190, 870-874.
17. Hoshino,Y., Enomoto,N., Sakamoto,N., Kurosaki,M., Ikeda,T., Marumo,F. and Sato,C. (1993) Expression of the hepatocyte growth factor receptor in the regenerating rat liver. Cancer Lett., 71, 119-123.
18. Tatematsu,M., Mera,Y., Inoue,T., Satoh,K., Sato,K. and Ito,N. (1988) Stable phenotypic expression of glutathione S-transferase placental type and unstable phenotypic expression of γ-glutamyltransferase in rat liver preneoplastic and neoplastic lesions. Carcinogenesis, 9, 215-220.
19. Radaeva,S. and Steinberg,P. (1995) Phenotype and differentiation patterns of the oval cell lines OC/CDE 6 and OC/CDE 22 derived from the livers of carcinogen-treated rats. Cancer Res., 55, 1028-1038.
20. Rushmore,T.H., Harris,L., Nagai,M., Sharma,R.N., Hayes,M.A., Cameron,R.G., Murray,R.K. and Farber,E. (1988) Purification and characterization of P-52 (glutathione S-transferase-P or 7-7) from normal liver and putative preneoplastic liver nodules. Cancer Res., 48, 2805-2812.
21. Campbell,H.A., Pitot,H.C., Potter,V.R. and Laishes,B.A. (1982) Application of quantitative stereology to the evaluation of enzyme-altered foci in rat liver. Cancer Res., 42, 465-472.
22. Chomczynski,P. (1993) A reagent for the single-step simultaneous isolation of RNA. DNA and proteins from cell and tissue samples. BioTechniques, 15, 532-535.
23. Kohri,K. et al. (1993) Structure and expression of the mRNA encoding urinary stone protein (osteopontin). J. Biol. Chem., 268, 15180-15184.
24. Solt,D.B., Medline,A. and Farber,E. (1977) Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis. Am. J. Pathol., 88, 595-618.
25. Tatematsu,M., Ho,R.H., Kaku,T., Ekem,J.K. and Farber,E. (1984) Studies on the proliferation and fate of oval cells in the liver of rats treated with 2-acetylaminofluorene and partial hepatectomy. Am. J. Pathol., 114, 418-130.
26. Beer,D.G., Schwarz,M., Sawada,N. and Pitot,H.C. (1986) Expression of H-ras and c-myc protooncogenes in isolated γ-glutamyl transpeptidase-positive rat hepatocytes and in hepatocellular carcinomas induced by diethylnitrosamine. Cancer Res., 46, 2435-2441.
27. Nagy,P., Evarts,R.P., Marsden,E., Roach,J. and Thorgeirsson,S.S. (1988) Cellular distribution of c-myc transcripts during chemical hepatocarcinogenesis in rats. Cancer Res., 48, 5522-5527.
28. Suchy,B.K., Sarafoff,M., Kerler,R. and Rabes,H.M. (1989) Amplification, rearrangements, and enhanced expression of c-myc in chemically induced rat liver tumors in vivo and in vitro. Cancer Res., 49, 6781-6787.
29. Alison,M.R., Poulsom,R., Jeffery,R., Anilkumar,T.V., Jagoe,R. and Sarraf,C.E. (1993) Expression of hepatocyte growth factor mRNA during oval cell activation in the rat liver. J. Pathol., 171, 291-299.
30. Hu,Z., Evarts,R.P., Fujio,K., Marsden,E.R. and Thorgeirsson,S.S. (1993) Expression of hepatocyte growth factor and c-mer genes during hepatic differentiation and liver development in the rat. Am. J. Pathol., 142, 1823-1830.
31. Enomoto,K. and Farber,E. (1982) Kinetics of phenotypic maturation of remodeling of hyperplastic nodules during liver carcinogenesis. Cancer Res., 42, 2330-2335.
32. Tatematsu,M., Nagamine,Y. and Farber,E. (1983) Redifferentiation as a basis for remodeling of carcinogen-induced hepatocyte nodules to normal appearing liver. Cancer Res., 43, 5049-5058.
33. Selden,C. Johnstone,R., Darby,H., Gupta,S. and Hodgson,H.J. (1986) Human serum does contain a high molecular weight hepatocyte growth factor: studies pre- and post-hepatic resection. Biochem. Biophys. Res. Commun., 139, 361-366.
34. Gohda,E., Tsubouchi,H., Nakayama,H., Hirono,S., Sakiyama,O., Takahashi,K., Miyazaki,H., Hashimoto,S. and Daikuhara,Y. (1988) Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. J. Clin. Invest., 81, 414-419.
35. Selden,C., Farnaud,S., Ding,S.F., Habib,N., Foster,C. and Hodgson,H.J.F. (1994) Expression of hepatocyte growth factor mRNA, and c-met mRNA (hepatocyte growth factor receptor) in human liver tumors. J. Hepatol., 21, 227-234.
36. Shiota,G., Rhoads,D.B., Wang,T.C., Nakamura,T. and Schraidt,E.V. (1992) Hepatocyte growth factor inhibits growth of hepatocellular carcinoma cells. Proc. Natl Acad. Sci. USA. 89, 373-377.
37. Liu,M.-L., Mars,W.M. and Michalopoulos,G.K. (1995) Hepatocyte growth factor inhibits cell proliferation in vivo of rat hepatocellular carcinomas induced by diethylnitrosamine. Carcinogenesis, 16, 841-843.