Functional analysis of histones H2A and H2B in transcriptional repression in Saccharomyces cerevisiae

Molecular and Cellular Biology

Volumn 16, Issue 6, 1996, Pages 2545-2553

  Recht, Judith ^a   Dunn, Barbara ^b   Raff, Amanda ^a   Osley, Mary Ann ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE;

ARTICLE; CHROMATIN STRUCTURE; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION TERMINATION;

SACCHAROMYCES CEREVISIAE;

EID: 0029939581     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.6.2545     Document Type: Article

References (71)

1. Almouzni, G., M. Mechali, and A. Wolffe. 1991. Transcription complex disruption caused by a transition in chromatin structure. Mol. Cell. Biol. 11:655-665.
2. Aparicio, O. M., B. L. Billington, and D. E. Gottschling. 1991. Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae. Cell 66:1279-1287.
3. Arents, G., R. W. Burlingame, B. W. Wang, W. E. Love, and E. N. Moudrianakis. 1991. The nucleosomal core histone octamer at 3.1A resolution: a tripartite protein assembly and a left-handed superhelix. Proc. Natl. Acad. Sci. USA 88:10148-10152.
4. Arents, G., and E. N. Moudrianakis. 1993. Topography of the histone octamer surface: repeating structural motifs utilized in the docking of nucleo-somal DNA. Proc. Natl. Acad. Sci. USA 90:10489-10493.
5. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1988. Current protocols in molecular biology. Greene Publishing Associates and Wiley-Interscience, New York.
6. Baer, B. W., and D. Rhodes. 1983. Eukaryotic RNA polymerase II hinds to nucleosome cores from transcribed genes. Nature (London) 301:482-488.
7. Brent, R., and M. Ptashne. 1981. Mechanism of action of the lexA gene product. Proc. Natl. Acad. Sci. USA 78:4204-4208.
8. Chen, H., B. Li, and J. Workman. 1994. A histone-binding protein, nucleoplasmin, stimulates transcription factor binding to nucleosomes and factor-induced nucleosome disassembly. EMBO J. 13:380-390.
9. Chien, C. T., S. Buck, R. Sternglanz, and D. Shore. 1993. Targeting of SIR 1 protein establishes transcriptional silencing at HM loci and telomeres in yeast. Cell 75:531-541.
10. Clark-Adams, C., and F. Winston. 1987. The SPT6 gene is essential for growth and is required for δ-mediated transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 7:679-686.
11. dark-Adams, C. D., D. Norris, M. A. Osley, J. Fassler, and F. Winston. 1988. Changes in histone gene dosage alter transcription in yeast. Genes Dev. 2:150-159.
12. Compagnone-Post, P. Unpublished data.
13. Cooper, J. P., S. Roth, and R. Simpson. 1994. The global transcription regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure. Genes Dev. 8:1400-1410.
14. Côté, J., J. Quinn, J. L. Workman, and C. L. Peterson. 1994. Stimulation of GAL4 derivative binding to nuclcosomal DNA by the yeast SWI/SNF complex. Science 265:53-60.
15. Dollard, C., S. L. Ricupero-Hovasse, G. Natsoulis, J. D. Boeke, and F. Winston. 1994. SPT10 and SPT21 are required for transcription of particular histone genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 14:5223-5228.
16. Durrin, L., R. Mann, P. Kayne, and M. Grunstein. 1991. Yeast histone H4 N-terminal sequence is required for promoter activation in vivo. Cell 65:1023-1031.
17. Grunstein, M. 1990. Histone function in transcription. Annu. Rev. Cell Biol. 6:643-678.
18. Guarente, L. 1992. Mechanism and regulation of transcriptional activation in eukaryotes: conserved features from yeasts to humans, p. 1016-1027. In S. L. McKnight and K. Yamamoto (ed.), Transcriptional regulation. Cold Spring Harbor Laboratory, New York.
19. Han, M., and M. Grunstein. 1988. Nucleosome loss activates downstream promoters in vivo. Cell 55:1137-1145.
20. Hansen, J., and A. P. Wolffe. 1994. A role for histones H2A/H2B in chromatin folding and transcriptional repression. Proc. Natl. Acad. Sci. USA 91:2339-2343.
21. Hayes, J.J., D. J. Clark, and A. P. Wolffe. 1991. Histone contributions to the structure of DNA in the nucleosome. Proc. Natl. Acad. Sci. USA 88:6829-6833.
22. Hayes, J. J., and A. P. Wolffe. 1993. Histones H2A/H2B inhibit the interaction of transcription factor IIIA with the Xenopus borealis somatic 5S RNA gene in a nucleosome. Proc. Natl. Acad. Sci. USA 89:1229-1233.
23. Hecht, A., T. Laroche, S. Strahl-Bolsinger, S. Gasser, and M. Grunstein. 1995. Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 80:583-592.
24. Hirschhorn, J., S. A. Brown, C. D. Clark, and F. Winston. 1992. Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure. Genes Dev. 6:2288-2298.
25. Hirschhorn, J. N., A. L. Bortvin, S. L. Ricupero-Hovasse, and F. Winston. 1995. A new class of histone H2A mutations in Saccharomyces cerevisiae causes specific transcriptional defects in vivo. Mol. Cell. Biol. 15:1999-2009.
26. Imbalzano, A., H. Kwon, M. Green, and R. E. Kingston. 1994. Facilitated binding of TATA-binding protein to nucleosomal DNA. Nature (London) 370:481-485.
27. Johnson, L. M., G. Fisher-Adams, and M. Grunstein. 1992. Identification of a non-basic domain in the histone H4 N-terminus required for repression of the yeast silent mating loci. EMBO J. 11:2201-2209.
28. Johnson, L. M., P. S. Kayne, E. S. Kahn, and M. Grunstein. 1990 Genetic-evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in S. cerevisiae. Proc. Natl. Acad. Sci. USA 87:6286-6290.
29. Kaiser, C., S. Michaelis, and A. Mitchell. 1994. Methods in yeast genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
30. Kayne, P. S., U. Kim, M. Han, J. R. Mullen, F. Yoshizaki, and M. Grunstein. 1988. Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating type loci in yeast. Cell 55:27-39.
31. Keleher, C., M. J. Redd, J. Schultz, M. Carlson, and A. D. Johnson. 1992. Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68:709-719.
32. Kim, U.-J., M. Han, P. Kayne, and M. Grunstein. 1988. Effects of histone H4 depletion on the cell cycle and transcription of Saccharomyces cerevisiae. EMBO J. 7:2211-2219.
33. Knezetic, J. A., and D. Luse. 1986. The presence of nucleosomes on a DNA template prevents initiation by RNA polymerase II in vitro. Cell 45:95-104.
34. Kwon, H., A. Imbalzano, P. A. Khavari, R. E. Kingston, and M. Green. 1994. Nucleosome disruption and enhancement of activator binding by a human SWI/SNF complex. Nature (London) 370:477-481.
35. Laurenson, P., and J. Rine. 1992. Silencers, silencing, and heritable transcriptional states. Microbiol. Rev. 56:543-560.
36. Malone, E. A., J. S. Fassler, and F. Winston. 1993. Molecular and genetic characterization of SPT4, a gene important for transcription initiation in Saccharomyces cerevisiae. Mol. Gen. Genet. 237:449-459.
37. Mann, R., and M. Grunstein. 1992. Histone H3 N-terminal mutations allow hyperactivation of the yeast GALI gene in vivo. EMBO J. 11:3297-3306.
38. Matsui, T. 1987. Transcription of adenovirus 2 major late and peptide IX genes under conditions of in vitro nucleosome assembly. Mol. Cell. Biol. 7:1401-1408.
39. Megee, P. C., B. A. Morgan, B. A. Mittman, and M. M. Smith. 1990. Genetic analysis of histone H4: essential roles of lysines subject to reversible acetylation. Science 247:841-845.
40. Moran, L. 1994. Ph.D. thesis. Cornell University, Ithaca, N.Y.
41. Moran, L., D. Morris, and M. A. Osley. 1990. A yeast H2A-H2B promoter can be regulated by changes in histone gene copy number. Genes Dev. 4:752-763.
42. Natsoulis, G., F. Winston, and J. D. Boeke. 1994. The SPT10 and SPT21 genes of Saccharomyces cerevisiae. Genetics 136:93-105.
43. Neigeborn, L., J. L. Celenza, and M. Carlson. 1987. SSN20 is an essential gene with mutant alleles that suppress defects in SUC2 transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 7:672-678.
44. Norris, D., B. Dunn, and M. A. Osley. 1988. The effect of histone gene deletions on chromatin structure in Saccharomyces cerevisiae. Science 242:759-761.
45. Norris, D., and M. A. Osley. 1987. The two gene pairs encoding H2A and H2B play different roles in the Saccharomyces cerevisiae life cycle. Mol. Cell. Biol. 7:3473-3481.
46. Osley, M. A. Unpublished data.
47. Osley, M. A. 1991. The regulation of histone synthesis in the cell cycle. Annu. Rev. Biochem. 60:827-861.
48. Osley, M. A., J. Could, S. Kim, M. Kane, and L. Hereford. 1986. Identification of sequences in a yeast promoter involved in periodic transcription. Cell 45:537-544.
49. Osley, M. A., and D. Lycan. 1987. Trans-acting mutations that alter transcription of Saccharomyces cerevisiae histone genes. Mol. Cell. Biol. 32:4204-4210.
50. Owens-Hughes, T., and J. Workman. 1994. Experimental analysis of chromatin function in transcriptional control. Crit. Rev. Eukaryotic Gene Expression 4:403-441.
51. Paranjape, S., R. T. Kamakaka, and J. T. Kadonaga. 1994. Role of chromatin structure in the regulation of transcription by RNA polymerase II. Annu. Rev. Biochem. 63:265-297.
52. Park, E. C., and J. Szostak. 1990. Point mutations in the yeast histone H4 prevent silencing of the silent mating type locus HML. Mol. Cell. Biol. 10:4932-4934.
53. Piña, B. U. Bruggemier, and M. Beato. 1990. Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter. Cell 60:719-731.
54. Roth, S., L. Shimizu, L. Johnson, M. Grunstein, and R. S. Simpson. 1992. Stable nucleosome positioning and complete repression by the yeast α2 repressor are disrupted by amino terminal mutations in histone H4. Genes Dev. 6:411-425.
55. Schuster, T., M. Han, and M. Grunstein. 1986. Yeast histone H2A and H2B amino termini have interchangeable functions. Cell 45:445-451.
56. Sherwood, P., S.Tsang, and M. A. Osley. 1993. Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 13:28-39.
57. Sherwood, P. W., and M. A. Osley. 1991. Histone regulatory (hir) mutations suppress δ insertions alleles in Saccharomyces cerevisiae. Genetics 128:729-738.
58. Spector, M. 1994. Ph.D. thesis. Cornell University, Ithaca, N.Y.
59. Spector, M., and M. A. Osley. 1993. The HIR4-1 mutation defines a new class of histone regulatory genes in Saccharomyces cerevisiae. Genetics 135:25-34.
60. Swanson, M., E. A. Malone, and F. Winston. 1991. SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat. Mol. Cell. Biol. 11:3009-3019.
61. Swanson, M. S., and F. Winston. 1992. SPT4, SPT5. and SPT6 interactions: effects on transcription and viability in Saccharomyces cerevisiae. Genetics 132:325-336.
62. Taylor, I. C. A., J. L. Workman, T. J. Schuetz, and R. E. Kingston. 1991. Facilitated binding of GAL4 and HSF to nucleosomal templates: differential function of DNA binding domains. Genes Dev. 5:1285-1298.
63. Thompson, J. S., X. Ling, and M. Grunstein. 1994. The histone H3 amino terminus is required for both telomeric and silent mating locus repression in yeast. Nature (London) 369:245-247.
64. Tzamarias, D., and K. Struhl. 1994. Functional dissection of the yeast Cyc8-Tup1 transcriptional co-repressor complex. Nature (London) 369:758-761.
65. van Holde, K. E. 1988. Chromatin. Springer-Verlag. New York.
66. Winston, F. Personal communication.
67. Winston, F. 1992. Analysis of SPT genes: a genetic approach toward analysis of TFIID, histones, and other transcription factors of yeast. p. 1271-1293. In S. L. McKnight and K. Yamamoto (ed.), Transcriptional regulation. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
68. Winston, F., and M. Carlson. 1992. Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection. Trends Genet. 8:387-391.
69. Wolffe, A. 1994. The transcription of chromatin templates. Curr. Opin. Genet. Dev. 4:245-254.
70. Workman, J. L., and R. G. Roeder. 1987. Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II. Cell 51:613-622.
71. Xu, H., U. H. Kim, T. Schusler, and M. Grunstein. 1992. Identification of a new set of cell cycle regulatory genes that regulate S-phase transcription of histonc genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 12:5249-5259.