Efficacy of triple DMARD therapy in patients with RA with suboptimal response to methotrexate

Journal of Rheumatology

Volumn 23, Issue SUPPL. 44, 1996, Pages 72-74

  O'Dell, James R ^a,b   Haire, Claire ^a,b   Erikson, Nils ^a,c   Drymalski, Walter ^a,d   Palmer, William ^a,e   Maloley, Pierre ^a   Klassen, Lynell W ^a,b   Wees, Steven ^a,e   Moore, Gerald F ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b Department of Internal Medicine ^*  (United States)

^c RAIN   (United States)

^d RAIN   (United States)

^e RAIN   (United States)

Author keywords

Combination therapy Methotrexate; DMARD; Hydroxychloroquine; Rheumatoid arthritis; Sulfasalazine

Indexed keywords

HYDROXYCHLOROQUINE; METHOTREXATE; SALAZOSULFAPYRIDINE; ANTIRHEUMATIC AGENT;

ADULT; AGED; CLINICAL ARTICLE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHEUMATOID ARTHRITIS; ARTICLE; DRUG COMBINATION; MIDDLE AGED; TREATMENT OUTCOME;

ADULT; AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; DRUG THERAPY, COMBINATION; HUMANS; HYDROXYCHLOROQUINE; METHOTREXATE; MIDDLE AGED; SULFASALAZINE; TREATMENT OUTCOME;

EID: 0029939391     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (25)

1. Hochberg MC: Adult and juvenile rheumatoid arthritis, current epidemiologic concepts Epidemiol Rev 1987;3:27-44.
2. Scott DL, Symmons DPM, Coulton BL, Popert AJ: Long-term outcome of treating rheumatoid arthritis: Results after 20 years. Lancet 1987;1:1108-11.
3. Vollertsen RS, Conn DL, Ballard DJ, Ilstrup DM, Kazmar RE, Silverfield JC: Rheumatoid vasculitis. Survival and associated risk factors. Medicine 1986;65:365-75.
4. Pincus T, Brooks RH, Callahan LF: Prediction of long-term mortality in patients with rheumatoid arthritis according to simple questionnaire and joint count measures. Ann Intern Med 1994;120:26-34.
5. Wolfe F, Mitchell DM, Sibley JT, et al: The mortality of rheumatoid arthritis. Arthritis Rheum 1994;37:481-94
6. Winchester R: The molecular basis of susceptibility to rheumatoid arthritis. Adv Immunol 1994;56:389-466.
7. Weyand CM, Goronzy JJ: Inherited and noninherited risk factors in rheumatoid arthritis Curr Opin Rheumatol 1995;7:206-13.
8. Goronzy JJ, Weyand CM: T and B cell-dependent pathways in rheumatoid arthritis. Curr Opin Rheumatol 1995;7:214-21.
9. Nepom GT, Nepom BS: Prediction of susceptibility to rheumatoid arthritis by human leukocyte antigen genotyping. Rheum Dis Clin North Am 1992;18:785-92.
10. O'Dell JR: The treatment of rheumatoid arthritis in 1995: Results of a survey (abstr). Arthritis Rheum 1995;(suppl)38:S366.
11. O'Dell J, Haire C, Erikson N, et al: Triple DMARD therapy for rheumatoid arthritis: Efficacy (abstr). Arthritis Rheum 1995;(suppl)38:R13
12. Arnett FC, Edworthy SM, Bloch DA, et al: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
13. Pinals RS, Masi AT, Larsen RA, et al: Preliminary criteria for clinical remission in rheumatoid arthritis Arthritis Rheum 1981;24:1308-15.
14. Paulus HE, Egger MJ, Ward JR, Williams, HJ, and the Cooperative Systematic Studies of the Rheumatic Diseases Group: Analysis of improvement in individual rheumatoid arthritis patients treated with disease modifying antirheumatic drugs, based on the findings in patients treated with placebo. Arthritis Rheum 1990;33:477-84.
15. Egger MJ, Huth DA, Ward JR, Reading JC, Williams HJ: Reduced joint count indices in the evaluation of rheumatoid arthritis. Arthritis Rheum 1985;28:613-9.
16. Wolfe F, Hawley DJ. Remission in rheumatoid arthritis. J Rheumatol 1985;12:245-52.
17. Alarcon GS, Blackburn WD, Calvo A, et al: Evaluation of the American Rheumatism Association preliminary criteria for remission in rheumatoid arthritis. J Rheumatol 1987;14:93-6.
18. Felson DT, Anderson JJ, Meenan RF: The efficacy and toxicity of combination therapy in rheumatoid arthritis. A meta-analysis. Arthritis Rheum 1994;31:1487-91.
19. Scott DL, Dawes PT, Tunn E, et al: Combination therapy with gold and hydroxychloroquine in rheumatoid arthritis: A prospective, randomized placebo-controlled study. Br J Rheumatol 1989;28:128-33.
20. Gibson T, Emery P, Armstrong RD, Crisp AJ, Panayi GS: Combined D-penicillamine and chloroquine treatment of rheumatoid arthritis. A comparative study. Br J Rheumatol 1987;26:279-84.
21. Taggart AJ, Hill J, Astbury C, Dixon JS, Bird HA, Wright V: Sulphasalazine alone or in combination with D-penicillamine in rheumatoid arthritis. Br J Rheumatol 1987;26:32-6.
22. Williams HJ, Ward JR, Reading JC, et al: Comparison of auranofin, methotrexate, and the combination of both in the treatment of rheumatoid arthritis A controlled clinical trial. Arthritis Rheum 1992;35:259-69.
23. Willkens RF, Urowitz MB, Stablein DM, et al. Comparison of azathioprine, methotrexate, and the combination of both in the treatment of rheumatoid arthritis: A controlled clinical trial. Arthritis Rheum 1992;35:849-56
24. Weinblatt ME, Kaplan H, Germain BF, et al. Methotrexate in rheumatoid arthritis. A five-year prospective multicenter study. Arthritis Rheum 1994;37:1492-8.
25. Weinblatt ME: Methotrexate in rheumatoid arthritis: A 5-year multicenter prospective trial (abstr) Arthritis Rheum 1995;36:S79