Transcriptional corepression in vitro: A Mot1p-associated form of TATA-binding protein is required for repression by Leu3p

Molecular and Cellular Biology

Volumn 16, Issue 4, 1996, Pages 1641-1648

  Wade, Paul A ^a,b   Jaehning, Judith A ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; RNA POLYMERASE II; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS INHIBITION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION;

DNA HELICASES; DNA-BINDING PROTEINS; FUNGAL PROTEINS; MUTATION; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TATA BOX; TATA-BINDING PROTEIN ASSOCIATED FACTORS; TATA-BOX BINDING PROTEIN; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0029939194     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.4.1641     Document Type: Article

References (55)

1. Andreadis, A., Y.-P. Hsu, G. B. Kohlhaw, and P. Schimmel. 1982. Nucleotide sequence of yeast LEU2 shows 5′-noncoding region has sequences cognate to leucine. Cell 31:319-325.
2. Auhle, D., and S. Hahn. 1993. An ATP-dependent inhibitor of TBP binding to DNA. Genes Dev. 7:844-856
3. Auble, D. T., K. E. Hansen, C. G. F. Mueller, W. S. Lane, J. Thorner, and S. Hahn. 1994. Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding by an ATP-dependent mechanism. Genes Dev. 8: 1920-1934.
4. Austin, R. J., and M. D. Biggin. 1995. A domain of even-skipped protein represses transcription by preventing TFIID binding to a promoter: repression by cooperative blocking. Mol. Cell. Biol. 15:4683-4693.
5. Brisco, P. R. G., and G. B. Kohlhaw. 1990. Regulation of yeast LEU2. J. Biol Chem. 265:11667-11675.
6. Chen, J.-L., L. D. Attardi, C. P. Verrijzer, K. Yokomori, and R. Tjian. 1994. Assembly of recombinant TFIID reveals differential coactivator requirments for distinct transcriptional activators Cell 79:93-105.
7. Chiang, C., H. Ge, Z. Wang, A. Hoffmann, and R. Roeder. 1993. Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III. EMBO J. 12:2749-2762.
8. Cortes, P., O. Flores, and D. Reinberg. 1992. Factors involved in specific transcription by mammalian RNA polymerase II: purification and analysis of transcription factor IIA and identification of transcription factor HJ. Mol. Cell. Biol. 12:413-421.
9. Davis, J. L., R. Kunisawa, and J. Thorner. 1992. A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 12:1879-1892.
10. Dynlacht, B. D., T. Hoey, and R. Tjian, 1991. Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation. Cell 66:563-576.
11. Field, J., J.-I. Nikawa, D. Broek, B. MacDonald, L. Rodgers, I. A. Wilson, R. A. Lerner, and M. Wigler. 1988. Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Mol. Cell. Biol. 8:2159-2165.
12. Friden, P., and P. Schimmel. 1988. LEU3 of Saccharomyces cerevisiae activates multiple genes for branched-chain amino acid biosynthesis by binding to a common decanucleotide core sequence. Mol. Cell. Biol. 8:2690-2697.
13. Ge, H., and R. Roeder. 1994. The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein. J. Biol. Chem. 269:17136-17140.
14. Gietz, D., A. St. Jean, R. A. Woods, and R. H. Schiestl. 1992. Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20:1425.
15. Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y
16. Hisatake, K., S. Hasegawa, R. Takada, Y. Nakatani, M. Horikoshi, and R. G. Roeder. 1993. The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCGI. Nature (London) 362:179-181.
17. Hu, Y., T. G. Cooper, and G. B. Kohlhaw. 1995. The Saccharomyces cerevisiae Leu3 protein activates expression of GDH1, a key gene in nitrogen assimilation. Mol. Cell. Biol. 15:52-57.
18. II30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor. Cell 79:107-117.
19. Kim, Y.-J., S. Bjorkland, Y. Li, M. H. Sayre, and R. D. Kornberg. 1994. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II Cell 77:599-608.
20. Kokubo, T., D. Gong, R. Roeder, M. Horikoshi, and Y. Nakatani. 1993. The Drosophila 110-kDa transcription factor TFIID subunit directly interacts with the N-terminal region of the 230-kDa subunit. Proc. Natl. Acad. Sci. USA 90:5896-5900.
21. Kokubo, T., D. Gong, S. Yamashita, M. Horikoshi, R. Roeder, and Y. Nakatani. 1993. Drosophila 230-kD TFIID subunit, a functional homolog of the human cell cycle gene product, negatively regulates DNA binding of the TATA box-binding subunit of TFIID. Genes Dev. 7:1033-1046.
22. Koleske, A., and R. Young. 1994. An RNA polymerase II holoenzyme responsive to activators. Nature (London) 368:466-469.
23. Komachi, K., M. J. Redd, and A. D. Johnson. 1994. The WD repeats of Tup1 interact with the homeo domain protein a2 Genes Dev. 8:2857-2867.
24. Kuchin, S., P. Yeghian, and M. Carlson. 1995. Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast Proc. Natl. Acad. Sci. USA 92:4006-4010
25. Paranjape, S. M., R. T. Kamakaka, and J. T. Kadonaga. 1994. Role of chromatin in the regulation of transcription by RNA polymerase II. Annu. Rev. Biochem. 63:265-298.
26. Parthun, M. R., D. A. Mangus, and J. A. Jaehning. 1992. The EGDI product, a yeast homolog of human BTF3, may be involved in GAL4 DNA binding. Mol. Cell. Biol. 12:5683-5689.
27. Poon, D., A. M. Campbell, Y. Bai, and P. A. Weil. 1994. Yeast Taf170 is encoded by MOT1 and exists in a TATA box-binding protein (TBP)-TBP-associated factor complex distinct from transcription factor IID. J. Biol. Chem. 269:23135-23140.
28. Poon, D., and P. Weil. 1993. Immunopurification of yeast TATA-binding protein and associated factors. J. Biol. Chem. 268:15325-15328.
29. Pugh, B. F., and R. Tjian. 1991. Transcription from a TATA-less promoter requires a multisubunit TFIID complex. Genes Dev. 5:1935-1945.
30. Reddy, P., and S. Hahn. 1991. Dominant negative mutations in yeast TFIID define a bipartite DNA-binding region. Cell 65:349-357.
31. Reese, J. C., L. Apone, S. S. Walker, L. A. Griffen, and M. R. Green. 1994 Yeast TAFIIs in a multisubunit complex required for activated transcription. Nature (London) 371:523-527.
32. Remboutsika, E., and G. Kohlhaw. 1994. Molecular architecture of a Leu3p-DNA complex in solution: a biochemical approach. Mol. Cell. Biol. 14: 5547-5557.
33. Ronne, H. 1995. Glucose repression in fungi. Trends Genet. 11:12-17.
34. II250: a TBP-associated factor implicated in cell-cycle regulation. Nature (London) 362:175-179.
35. Sauer, F., J. D. Fondell, Y. Ohkuma, R. G. Roeder, and H. Jâckle. 1995. Control of transcription by Krüppel through interactions with TFIIB and TFIIEβ. Nature (London) 375:162-164.
36. Sayre, M. H., H. Tschochner, and R. D. Kornberg. 1992. Reconstitution of transcription with five purified initiation factors and RNA polymerase II from Saccharomyces cerevisiae. J. Biol Chem. 267:23376-23382.
37. Sikorski, R. S., M. S. Boguski, M. Goebl, and P. Hieter. 1990. A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis. Cell 60:307-317.
38. Sze, J.-Y., and G. B. Kohlhaw. 1993. Purification and structural characterization of transcriptional regulator Leu3 of yeast. J. Biol. Chem. 268:2505-2512
39. Sze, J.-Y., E. Remboutsika, and G. B. Kohlhaw. 1993. Transcriptional regulator Leu3 of Saccharomyces cerevisiae: separation of activator and repressor functions. Mol. Cell. Biol. 13:5702-5709.
40. Sze, J.-Y., M. Woontner, J. A. Jaehning, and G. B. Kohlhaw. 1992. In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on α-isopropylmalate. Science 258:1143-1145.
41. Tjian, R., and T. Maniatis. 1994 Transcriptional activation: a complex puzzle with few easy pieces. Cell 77:6-8.
42. Tsai, M.-J., and B. W. O'Malley. 1994. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu. Rev. Biochem. 63:451-486.
43. Tzamarias, D., and K. Struhl. 1995. Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters. Genes Dev. 9:821-831.
44. Um, M., C. Li, and J. L. Manley. 1995. The transcriptional repressor Even-skipped interacts directly with the TATA-binding protein. Mol. Cell. Biol. 15:5007-5016.
45. II150. similarity to yeast gene TSM-1 and specific binding to core promoter DNA. Science 264:933-941.
46. Wade, P. A., and J. A. Jaehning. 1994. Isolation of yeast transcription factor IIA using a functional transcription assay. Protein Expr Purif. 5:577-582
47. Wade, P. A., S. D. Shaffer, and J. A. Jaehning. 1993. Resolution of transcription factors from a transcriptionally active whole-cell extract from yeast, purification of TFIIB, TBP and RNA polymerase IIa. Protein Expr. Purif 4: 290-297.
48. Wahi, M., and A. D. Johnson. 1995. Identification of genes required for α2 repression in Saccharomyces cerevisiae. Genetics 140:70-90.
49. Weintraub, S. J., K. N. B. Chow, R. X. Luo, S. H. Zhang, S. He, and D. C. Dean. 1995. Mechanisms of active transcriptional repression by the retinoblastoma protein. Nature (London) 375:812-815.
50. Weinzierl, R. O., B. D. Dynlacht, and R. Tjian. 1993. Largest subunit of Drosophila transcription factor IID directs assembly of a complex containing TBP and a coactivator. Nature (London) 362:511-517.
51. Winkley, C. S., M. J. Keller, and J. A. Jaehning. 1985. A multicomponent mitochondrial RNA polymerase from Saccharomyces cerevisiae. J. Biol Chem. 260:14214-14223.
52. Woontner, M., and J. A. Jaehning. Unpublished data.
53. Woontner, M., P. A. Wade, J. Bonner, and J. A. Jaehning. 1991. Transcriptional activation in an improved whole-cell extract from Saccharomyces cerevisiae. Mol. Cell. Biol. 11:4555-4560.
54. Zhou, Q., P. M. Lieberman, T. G. Boyer, and A. J. Berk. 1992. Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter. Genes Dev. 6:1964-1974.
55. Zitomer, R. S., and C. V. Lowry. 1992. Regulation of gene expression by oxygen in Saccharomyces cerevisiae. Microbiol. Rev 56:1-11.