Salt-sensitive hypertension in (mREN-2)27 transgenic rats

Hypertension

Volumn 27, Issue 3 II, 1996, Pages 573-577

  Callahan, Michael F ^a   Li, Ping ^b   Ferrario, Carlos M ^b   Ganten, Detlev ^b   Morris, Mariana ^b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

angiotensin; appetite; drinking; heart rate; renin; vasopressins; water electrolyte balance

Indexed keywords

ANGIOTENSIN; RENIN; VASOPRESSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APPETITE; CONFERENCE PAPER; CONTROLLED STUDY; DRINKING; ELECTROLYTE BALANCE; FLUID BALANCE; HEART RATE; HYPERTENSION; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TRANSGENIC ANIMAL;

EID: 0029939004     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.hyp.27.3.573     Document Type: Conference Paper

References (40)

1. Mullins JJ, Peters J, Ganten D. Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene. Nature. 1990; 344:541-544.
2. Tokita Y, Franco-Saenz R, Mulrow PJ, Ganten D. Effects of nephrectomy and adrenalectomy on the renin-angiotensin system of transgenic rats TGR(mRen2)27. Endocrinology. 1994;134: 253-257.
3. Moriguchi A, Brosnihan KB, Kumagai H, Ganten D, Ferrario CM. Mechanisms of hypertension in transgenic rats expressing the mouse Ren-2 gene. Am J Physiol. 1994;266:R1273-R1279.
4. d renin gene in transgenic hypertensive rats, TGR(mREN2)27. Am J Physiol. 1993;265:E699-E707.
5. Lee MA, Bohm M, Kim S, Bachmann S, Bachmann J, Bader M, Ganten D. Differential gene expression of renin and angiotensinogen in the TGR(mREN-2)27 transgenic rat. Hypertension. 1995; 25:570-580.
6. Senanayake P, Moriguchi A, Kumagai H, Ganten D, Ferrario CM, Brosnihan KB. Increased expression of angiotensin peptides in the brain of transgenic hypertensive rats. Peptides. 1994;15:919-926.
7. Peters J, Munter K, Bader M, Hackenthal E, Mullins JJ, Ganten D. Increased adrenal renin in transgenic hypertensive rats, TGR (mREN2)27, and its regulation by cAMP, angiotensin, and calcium. J Clin Invest. 1993;91:742-747.
8. Sander M, Bader M, Djavidani B, Maser-Gluth C, Vecsei P, Mullins J, Ganten D, Peters J. The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27. Endocrinology. 1992; 131:807-814.
9. Bader M, Zhao Y, Sander M, Lee MA, Bachmann J, Bohm M, Djavidani B, Peters J, Mullins JJ, Ganten D. Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats. Hypertension. 1992;19:681-686.
10. Moriguchi A, Tallant EA, Matsumura K, Reilly TM, Walton H, Ganten D, Ferrario CM. Opposing actions of angiotensin-(1-7) and angiotensin II in the brain of transgenic hypertensive rats. Hypertension. 1995;25:1260-1265.
11. Unger T, Becker H, Petty M, Demmert G, Schneider B, Ganten D, Lang RE. Differential effects of central angiotensin II and substance P on sympathetic nerve activity in conscious rats: implications for cardiovascular adaptation to behavioral responses. Circ Res. 1985;56:563-575.
12. Hutchinson JS, Schelling P, Mohring J, Ganten D. Pressor action of centrally perfused angiotensin II in rats with hereditary hypothalamic diabetes insipidus. Endocrinology. 1976;99:819-823.
13. Fink GD, Bruner CA. Hypertension during chronic peripheral and central infusion of angiotensin III. Am J Physiol. 1985;249: E201-E208.
14. Epstein AN. Neurohormonal control of salt intake in the rat. Brain Res Bull. 1991;27:315-320.
15. Jandhyala BS, Lokhandwala MF, Nandiwada P, Buckley JP. Circulatory effects of chronic administration of angiotensin II into the cerebrolateral ventricles of dogs. Hypertension. 1979;1:219-227.
16. Katahira K, Mikami H, Ogihara T, Kohara K, Otsuka A, Kumahara Y, Khosla MC. Synergism of intraventricular NaCl infusion and subpressor angiotensins in rats. Am J Physiol. 1989;256:H1-H8.
17. Ando K, Sato Y, Fujita T. Salt sensitivity in hypertensive rats with angiotensin II administration. Am J Physiol. 1990;259: R1012-R1016.
18. Bruner CA, Weaver JM, Fink GD. Sodium-dependent hypertension produced by chronic central angiotensin II infusion. Am J Physiol. 1985;249:H321-H327.
19. Möhring J, Möhring B. Evaluation of sodium and potassium balance in rats. J Appl Physiol. 1972;33:688-692.
20. da Rocha MJA, Callahan MF, Sundberg DK, Morris M. Sinoaortic denervation alters the molecular and endocrine responses to salt loading. Neuroendocrinology. 1993;57:729-739.
21. Barrett GL, Mullins JJ. Studies on blood pressure regulation in hypertensive ren-2 transgenic rats. Kidney Int. 1992;41(suppl): S125-S128.
22. Chung O, Schips T, Rohmeiss P, Gretz P, Strauch M, Unger T. Protein excretion and renal adaptation of transgenic mRen2 rats to changing oral sodium loads. J Hypertens. 1993;11:S188-S189.
23. Li P, Callahan MF, Ferrario CM, Ganten D, Morris M. Salt loading increases catecholamine secretion and arterial pressure in mREN-2 transgenic rats. Soc Neurosci Abstr. 1995;21:1407. Abstract.
24. Kreiger JE, Roman RJ, Cowley AW Jr. Hemodynamics and blood volume in angiotensin II salt-dependent hypertension in dogs. Am J Physiol. 1989;257:H1402-H1412.
25. Hinojosa-Laborde C, Thunhorst RL, Cowley AW Jr. Vasoconstriction during volume expansion is independent of central control. Hypertension. 1990;15:712-717.
26. Lo M, Medeiros IA, Mullins JJ, Ganten D, Barres C, Cerutti C, Vincent M, Sassard J. High blood pressure maintenance in transgenic mRen-2 vs Lyon genetically hypertensive rats. Am J Physiol. 1993;265:R180-R186.
27. Hirth-Dietrich C, Stasch J-P, Ganten D, Luft FC. Renal effects of captopril and nitrendipine in transgenic rats with an extra renin gene. Hypertension. 1994;23:626-631.
28. Gross V, Roman RJ, Cowley AW Jr. Abnormal pressure-natriuresis in transgenic renin gene rats. J Hypertens. 1994;12: 1029-1034.
29. Matsuguchi M, Schmid PG, Van Orden D, Mark AL. Does vasopressin contribute to salt-induced hypertension in the Dahl strain? Hypertension. 1981;3:174-181.
30. Morris M, Alexander N. Baroreceptor influences on oxytocin and vasopressin secretion. Hypertension. 1989;13:110-114.
31. Moriguchi A, Ferrario CM, Brosnihan KB, Ganten D, Morris M. Differential regulation of central vasopressin in transgenic rats harboring the mouse Ren-2 gene. Am J Physiol. 1994;267: R786-R791.
32. Pawloski CM, Eicker NM, Ball LM, Mangiapane ML, Fink GD. Effect of circulating vasopressin on arterial pressure regulation in rats. Am J Physiol. 1989;257:H209-H218.
33. Szczepanska-Sadowska E, Stepniakowski K, Skelton MM, Cowley AW Jr. Prolonged stimulation of intrarenal V1 vasopressin receptors results in sustained hypertension. Am J Physiol. 1994;267: R1217-R1255.
34. Avrith DB, Fitzsimons JT. Renin-induced sodium appetite: effects on sodium balance and mediation by angiotensin in the rat. J Physiol. 1983;337:479-496.
35. Phillips MI. Functions of angiotensin in the central nervous system. Annu Rev Physiol. 1987;49:413-435.
36. Cowley AW, McCaa RE. Acute and chronic dose-response relationships for angiotensin, aldosterone, and arterial pressure at varying levels of sodium intake. Circ Res. 1976;39:788-797.
37. Bruner CA, Fink GD. Neurohumoral contributions to chronic angiotensin-induced hypertension. Am J Physiol. 1986;250:H52-H61.
38. Kanagy NL, Pawloski CM, Fink GD. Role of aldosterone in angiotensin II-induced hypertension in rats. Am J Physiol. 1990;259: R102-R109.
39. Fink GD, Bruner CA, Mangiapane ML. Area postrema is critical for angiotensin-induced hypertension in rats. Hypertension. 1987;9: 355-361.
40. Averill DB, Matsumura K, Ganten D, Ferrario CM. Role of area postrema in transgene hypertension. Hypertension. 1996;27(part 2): 591-597.