Synthesis and lipase-catalyzed resolution of 5-(hydroxymethyl)-1,3-dioxolan-4-ones: Masked glycerol analogs as potential building blocks for pharmaceuticals

Journal of Organic Chemistry

Volumn 61, Issue 10, 1996, Pages 3423-3427

  Hof, Robert P ^a   Kellogg, Richard M ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; TRIACYLGLYCEROL LIPASE;

ARTICLE; DRUG PURIFICATION; DRUG SYNTHESIS; ENANTIOMER; ENZYME ACTIVITY; TECHNIQUE;

EID: 0029938623     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo952021v     Document Type: Article

References (28)

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28. This experiment was performed only once to establish the absolute stereochemistry of 8a. So far, no attempts have been undertaken to improve yields or shorten reaction times.