High-performance liquid chromatographic assay of mepivacaine enantiomers in human plasma in the nanogram per milliliter range

Journal of Chromatography B: Biomedical Applications

Volumn 678, Issue 2, 1996, Pages 369-372

  Vletter, Arie A ^a   Olieman, Wim ^a   Burm, Anton G L ^a   Groen, Kees ^b   Van Kleef, Jack W ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

Enantiomer separation; Mepivacaine

Indexed keywords

MEPIVACAINE;

ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; NORMAL HUMAN; PRIORITY JOURNAL; TECHNIQUE; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0029938489     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4347(95)00568-4     Document Type: Article

References (8)

1. G. Åberg, Acta Pharmacol. Toxicol., 31 (1972) 273-286.
2. F.P. Luduena, E.F. Bogado and B.F. Tullar, Arch. Int. Pharmacodyn., 200 (1972) 359-369.
3. L.E. Mather, Br. J. Anaesth., 67 (1991) 239-246.
4. T.B. Vree, E.M.C. Beumer, A.J. Lagerwerf, M.A.M. Simon and M.J.M. Gielen, Anesth. Analg., 75 (1992) 75-80.
5. A.G.L. Burm, A.D. van der Meer, J.W. van Kleef, P.W.M. Zeijlmans and K. Groen, Br. J. Clin. Pharmacol., 38 (1994) 125-129.
6. A.G.L. Burm, Clin. Pharmacokin., 16 (1989) 283-311.
7. J. Hermansson, J. Chromatogr., 298 (1984) 67-78.
8. B.Th. Veering, A.G.L. Burm, M.P.R.R. Gladines and J. Spierdijk, Br. J. Clin. Pharmacol., 32 (1991) 501-503.