Cellular or viral protein binding to a cytomegalovirus promoter transcription initiation site: Effects on transcription

Journal of Virology

Volumn 70, Issue 6, 1996, Pages 3628-3635

  Macias, Mimi P ^a   Huang, Liping ^a   Lashmit, Philip E ^a   Stinski, Mark F ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN;

ARTICLE; AUTOREGULATION; BINDING SITE; CYTOMEGALOVIRUS; DNA FOOTPRINTING; DNA TEMPLATE; IMMEDIATE EARLY GENE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DNA INTERACTION; TATA BOX; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; VIRUS GENOME;

EID: 0029938479     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.6.3628-3635.1996     Document Type: Article

References (47)

1. Carcamo, J., L. Buckbinder, and D. Reinberg. 1991. The initiator directs the assembly of a transcript factor IID-dependent transcription complex. Proc. Natl. Acad. Sci. USA 88:8052-8056.
2. Cherrington, J. M., E. L. Khourv, and E. S. Mocarski. 1991. Human cytomegalovirus ie2 negatively regulates a gene expression via a short target sequence near the transcription start site. J. Virol. 65:887-896.
3. Chiou, C.-J., J. Zong, I. Waheed, and G. S. Hayward. 1993. Identification and mapping of dimerization and DNA-hinding domains in the C terminus of the IE2 regulatory protein of human cytomegalovirus. J. Virol. 67:6201-6214.
4. Du, H., A. L. Roy, and R. G. Roeder. 1993. Human transcription factor USF stimulates transcription through the initiator elements of the HIV-1 and the Ad-ML promoters. EMBO J. 12:501-511.
5. Furnari, B. A., E. Poma, T. F. Kowalik, S.-M. Huong, and E.-S. Huang. 1993. Human cytomegalovirus immediate-early gene 2 protein interacts with itself and with several novel cellular proteins. J. Virol. 67:4981-4991.
6. Ghazal, P., H. Lubon, B. Fleckenslein, and L. Henninghausen. 1987. Binding of transcription factors and creation of a large nucleoprotein complex on the human cytomegalovirus enhancer. Proc. Natl. Acad. Sci. USA 84:3658-3662.
7. Hansen, S. K., and R. Tjian. 1995. TAFs and TFIIA mediate differential utilization of the tandem Adh promoters. Cell 82:565-575.
8. Hermiston, T. W., C. L. Malone, and M. F. Stinski. 1990. Human cytomegalovirus immediate-early two protein region involved in negative regulation of the major immediate-early promoter. J. Virol. 64:3532-3536.
9. Hermislon, T. W., C. L. Malone, P. R. Witte, and M. F. Stinski. 1987. Identification and characterization of the human cytomegalovirus immediate-early region 2 gene that stimulates gene expression from an inducihle promoter. J. Virol. 61:3214-3221.
10. Ho, M. 1990. Epidemiology of cytomegalovirus infections. Rev. Infect. Dis. 12:5701-5710.
11. Javahery, R., A. Khachi, K. Lo, B. Zenzie-Gregory, and S. T. Smale. 1994. DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol. Cell. Biol. 14:116-127.
12. Jupp, R., S. Hoffmann, A. Depto, R. M. Stenberg, P. Ghazal, and J. A. Nelson. 1993. Direct interaction of the human cytomegalovirus IE86 protein with the cis repression signal does not preclude TBP from binding to the TATA box. J. Virol. 67:5595-5604.
13. Kaufmann, J., and S.T. Smale. 1994. Direct recognition of initiator elements by a component of the transcription factor IID complex. Genes Dev. 8:821-829.
14. Kondo, K., H. Kaneshima, and E. S. Mocarski. 1994. Human cytomegalovirus latent infections of granulocyte-macrophage progenitors. Proc. Natl. Acad. Sci. USA 91:11879-11883.
15. Kuwabara, M. D., and D. S. Sigman. 1987. Footprinting DNA-protein complexes in situ following gel retardation assays using 1,10-phenanthrolinecopper ion: Escherichia coli RNA polymerase-lac promoter complexes. Biochemistry 26:7234-7238.
16. Lang, D., and T. Stamminger. 1993. The 86-kilodalton IE-2 protein of human cytomegalovirus is a sequence-specific DNA-binding protein that interacts directly with the negative autoregulatory response element located near the cap site of the IE-1/2 enhancer-promoter. J. Virol. 67:323-331.
17. Lang, D., and T. Stamminger. 1994. Minor groove contacts are essential for an interaction of human cytomegalovirus IE2 protein with its DNA target. Nucleic Acids Res. 22:3331-3338.
18. Liu, B., T. W. Hermislon, and M. F. Stinski. 1991. A cis-acting element in the major immediate-early (IE) promoter of human cytomegalovirus is required for negative regulation by IE2. J. Virol. 65:897-903.
19. Macias, M. P., and M. F. Slinski. 1993. An in vitro system for human cytomegalovirus immediate early 2 protein (IE2)-mediated site-dependent repression of transcription and direct binding of IE2 to the major immediate early promoter. Proc. Natl. Acad. Sci. USA 90:707-711.
20. 19a.Macias, M. P., and M. F. Stinski. Unpublished data.
21. Malone, C. L., D. H. Vesole, and M. F. Stinski. 1990. Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins. J. Virol. 64:1498-1506.
22. Marlinez, E., C.-M. Chiang, H. Ga, and R. G. Roeder. 1994. TATA-binding protein-associated factor(s) in TFIID function through the initiator to direct basa) transcription from a TATA-less class II promoter. EMBO J. 13:3115-3126.
23. Means, A. L., J. E. Slansky, S. L. McMahon, M. W. Knuth, and P. J. Farnham. 1992. The HIP-1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter. Mol. Cell. Biol. 12:1054-1063.
24. Pizzorno, M. C., and G. S. Hayward. 1990. The IE2 gene products of human cytomegalovirus specifically down-regulate expression from the major immediate-early promoter through a target sequence located near the cap site. J. Virol. 64:6154-6165.
25. Pizzorno, M. C., P. O'Hara, L. Sha, R. L. LaFemina, and G. S. Hayward. 1988. trans-activation and autoregulation of gene expression by the immediate-early region 2 gene products of human cytomegalovirus. J. Virol. 62: 1167-1179.
26. Rawlinson, W. D., and B. G. Barrell. 1993. Spliced transcripts of human cytomegalovirus. J. Virol. 67:5502-5513.
27. Roy, A. L., M. Meisterernst, P. Pognonec, and R. G. Roeder. 1991. Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF. Nature (London) 354:245-248.
28. Sambrook, J. E. F. Fritsch, and T. Manialis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
29. Santomenna, L. D., and P. A. Colberg. 1990. Induction of cellular hsp70 expression by human cytomegalovirus. J. Virol. 64:2033-2040.
30. Seto, E., Y. Shi, and T. Shenk. 1991. YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro. Nature (London) 354:241-245.
31. Smale, S. T., and D. Baltimore. 1989. The initiator as a transcription control element. Cell 57:103-113.
32. Stamminger, T., E. Puchtler, and B. Fleckenstein. 1991. Discordant expression of the immediate-early 1 and 2 gene regions of human cytomegalovirus at early times after infection involves posttranscriptional processing events. J. Virol. 65:2273-2282.
33. Stenberg, R. M., A. S. Depto, J. Fortney, and J. A. Nelson. 1989. Regulated expression of early and late RNAs and proteins from the human cytomegalovirus immediate-early gene region. J. Virol. 63:2699-2708.
34. Stenberg, R. M., J. Fortney, S. W. Barlow, B. P. Magrane, J. A. Nelson, and P. Ghazal. 1990. Promoter-specific transactivation and repression of human cytomegalovirus immediate-early proteins involve common and unique protein domains. J. Virol. 64:1556-1565.
35. Stenberg, R. M., D. R. Thomsen, and M. F. Slinski. 1984. Structural analysis of the major immediate early gene of human cytomegalovirus. J. Virol. 49:190-199.
36. Stinski, M. F. 1990. Cytomegalovirus and its replication, p. 1959-1980. In B. N. Fields, D. M. Knipe, et al. (ed.). Virology, 2nd ed. Raven Press. New York.
37. Stinski, M. F., M. P. Macias, C. L. Malone, A. R. Thrower, and L. Huang. 1993. Regulation of transcription from the major immediate early promoter by cellular and viral proteins, p. 3-12. In S. Michclson and S. A. Plotkin (ed.), Multidisciplinary approach to understanding cytomegalovirus disease. Elsevier Science Publishing Company, Inc., Amsterdam.
38. Stinski, M. F., and T. J. Roehr. 1985. Activation of the major immediate early gene of human cytomegalovirus by cis-acting elements in the promoterregulatory sequence and by virus-specific (ran.v-acting components. J. Virol. 55:431-441.
39. Taylor-Wiedeman, J., J. G. P. Sissons, L. K. Borysiewicz, and J. H. Sinclair. 1991. Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells. J. Gen. Virol. 72:2059-2064.
40. Thomsen, D. R., R. M. Stenberg, W. F. Goins, and M. F. Stinski. 1984. Promoter-regulatory region of the major immediate early gene of human cytomegalovirus. Proc. Natl. Acad. Sci. USA 81:659-663.
41. 39a.Tjian, R. Personal communication.
42. Usheva, A., and T. Shenk. 1994. TATA-binding protein independent initiation: YY1, TFIIB and RNA polymerase II direct basal transcription on supercoiled template DNA. Cell 76:1115-1121.
43. Verrjjzer, C. P., J.-L. Chen, K. Yokomori, and R. Tjian. 1995. Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II. Cell 81:1115-1125.
44. Verifier, C. P., K. Yokomori, J.-L. Chen, and R. Tjian. 1994. Drosophila TAFI1150: similarity to yeast gene TSM-1 and specific binding to core promoter DNA. Science 264:933-941.
45. Wathen, M. W., and M. F. Stinski. 1982. Temporal patterns of human cytomegalovirus transcription: mapping the viral RNAs synthesized at immediate early, early, and late times after infection. J. Virol. 41:462-477.
46. Williams, M., A. Brys, A. M. Weiner, and N. Maizels. 1992. A rapid method for determining the molecular weight of a protein bound to nucleic acid in a mobility shift assay. Nucleic Acids Res. 20:4935-4936.
47. Wu, J., R. Jupp, R. M. Stenberg, J. A. Nelson, and P. Ghazal. 1993 Sitespecific inhibition of RNA polymerase II preinitiation complex assembly by human cytomegalovirus IE86 protein. J. Virol. 67:7547-7555.