Homologous desensitization of human corticotropin-releasing factor1 receptor in stable transfected mouse fibroblast cells

Brain Research

Volumn 710, Issue 1-2, 1996, Pages 287-292

  Dieterich, Klaus D ^a,b   Grigoriadis, Dimitri E ^a   De Souza, Errol B ^a,b  

^a NEUROCRINE BIOSCIENCES INC   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adenylate cyclase activity; Adrenocorticotropin; cAMP production; Corticotropin releasing factor; Pituitary; Receptor downregulation

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR; CYCLIC AMP;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FIBROBLAST; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DOWN REGULATION;

ADENYLATE CYCLASE; ANIMALS; CATTLE; CORTICOTROPIN-RELEASING HORMONE; CYCLIC AMP; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; HUMANS; MICE; RATS; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; SHEEP; TRANSFECTION;

EID: 0029937942     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(95)01480-2     Document Type: Article

References (49)

1. Anderson, S.M., Kant, G.J. and De Souza, E.B., Effects of chronic stress on brain and pituitary corticotropin-releasing factor (CRF) receptors, Pharmacol. Biochem. Behav., 44 (1993) 755-761.
2. Angelucci, L. and Scaccianoce, S., Mechanisms in the control of stress responsiveness, Ann. 1st Super Sanita, 26 (1990) 75-78.
3. Bilezikjian, L.M. and Vale, W.W., Glucocorticoids inhibit corticotropin-releasing factor-induced production of adenosine 3′,5′-monophosphate in cultured anterior pituitary cells, Endocrinology, 113 (1983) 657-662.
4. Chang, C.-P., Pearse II, R.V., O'Connell, S. and Rosenfeld, M.G., Identification of a seven transmembrane helix receptor for corticotropin-releasing-factor and sauvagine in mammalian brain, Neuron, 11 (1993) 1187-1195.
5. Chalmers, D.T., Lovenberg, T.W., Grigoriadis, D.E. and De Souza, E.B., Corticotropin-releasing factor receptors: from molecular cloning to drug design, TIPS (in press).
6. Castro, M.G., Effects of corticotropin-releasing factor and arginine-vasopressin on proopiomelanocortin (POMC) mRNA levels, release and storage of adrenocorticotrophin from mouse anterior pituitary cells, Comp. Biochem. Physiol., 104A (1993) 105-112.
7. Chadwick, D.J., Marsh, J. and Ackrill, K. (Eds.), Corticotropin-Releasing Factor, Ciba Foundation Symposium 172, John Wiley, Chichester, UK, 1993.
8. Chen, R., Lewis, K.A., Perrin, M.H. and Vale, W.W., Expression cloning of a human corticotropin-releasing factor receptor, Proc. Natl. Acad. Sci. USA, 90 (1993) 8967-8971.
9. Cyr, C. and Kris, R.M., Desensitization of human endothelin A receptor, J. Cardiovasc. Pharmacol. Suppl., 8 (1993) 11-14.
10. De Souza, E.B., Corticotropin-releasing factor receptor in the rat central nervous system: Characterization and regional distribution, J. Neuroscience, 7 (1987) 88-100.
11. De Souza, E.B., Corticotropin-releasing hormone receptors: In: Bjorlund, A., Hokfelt, T., Kuhar, M.J. (Eds.), Handbook of Chemical Neuroanatomy - Neuropeptide Receptors in the CNS, part III, Elsevier, Amsterdam, 1992, pp. 145-185.
12. De Souza, E.B., Corticotropin-releasing factor receptors: physiology, pharmacology, biochemistry and role in central nervous system and immune disorders, Psychoneuroendocrinology (in press).
13. De Souza, E.B. and Nemeroff, C.B. (Eds.), Corticotropin-releasing Factor: Basic and Clinical Studies of a Neuropeptide, CRC Press, Boca Raton, 1990.
14. De Souza, E.B. and Grigoriadis, D.E., Corticotropin-Releasing Factor: Physiology, pharmacology, and role in central nervous system and immune disorders. In F.E. Bloom and D.J. Kupfer (Eds.), Psychopharmacology: The Fourth Generation of Progress, Raven Press, New York, pp. 505-517, 1995.
15. De Souza, E.B., Perrin, M., Rivier, J., Vale, W.W. and Kuhar, M.J., Corticotropin-releasing factor receptors in rat pituitary gland: autoradiographic localization, Brain Res., 296 (1984) 202-207.
16. De Souza, E.B., Insel, T.R., Perrin, M., Rivier, J., Vale, W.W. and Kuhar, M.J., Differential regulation of corticotropin-releasing factor receptors in anterior and intermediate lobes of the pituitary and brain following adrenalectomy in rats, Neurosci. Lett., 56 (1985) 121-128.
17. De Souza, E.B., Whitehouse, P.J., Kuhar, M.J., Price, D.L. and Vale, W.W. Reciprocal changes in corticotropin-releasing factor (CRF)-like immunoreactivity and CRF receptors in cerebral cortex of Alzheimer's disease, Nature, 319 (1986) 593-595.
18. Dieterich, K.D., Grigoriadis, D.E. and De Souza, E.B. Corticotropin-releasing factor receptors in human small cell lung carcinoma cells: Radioligand binding, second messenger and northern blot analysis data, Endocrinology, 135 (1994) 1551-1558.
19. Dunn, A.J. and Berridge, C.W., Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety of stress responses?, Brain Res. Rev., 15 (1990) 71-100.
20. Grigoriadis, D.E. and De Souza, E.B., Corticotropin-releasing factor (CRF) receptors intermediate lobe of the pituitary: biochemical characterization and autoradiographic localization, Peptides, 10 (1989) 179-188.
21. Grigoriadis, T.W., Liaw, C.W., Oltersdorf, T. and De Souza, E.B., Pharmacological characterization of rat and human corticotropin-releasing factor (CRF) receptors expressed in stable cell lines, Soc. Neurosci. Abstr., 20 (1994) 552.7.
22. Giguere, V., Labrie, F., Cote, J., Coy, D.H., Suiras-Diaz, J. and Schally, A.V., Stimulation of cyclic AMP accumulation and corticotropin release by synthetic ovine corticotropin-releasing factor in rat anterior pituitary cells: site of glucocorticoid action, Proc. Natl. Acad. Sci. USA, 79 (1982) 3466-3469.
23. Hauger, R.L., Lorang, M., Irwin, M. and Aguilera, G., CRF receptor regulation and sensitization of ACTH responses to acute ether stress during chronic intermittent immobilization stress, Brain Res., 532 (1990) 34-40.
24. Hauger, R.L., Irwin, M.R., Lorang, M., Aguilera, G. and Brown, M.R., High intracerebral levels of CRH result in CRH receptor downregulation in the amygdala and neuroimmune desensitization, Brain Res., 616 (1993) 283-292.
25. Kapcala, L.P. and De Souza, E.B., Characterization of corticotropin-releasing factor receptors in dissociated brain cell cultures, Brain Res., 346 (1988) 159-167.
26. Kishimoto, T., Pearse II, R.V., Lin, C.R. and Rosenfeld, M.R., A sauvagine/ corticotropin-releasing factor receptor expressed in heart and skeletal muscle, Proc. Natl. Acad. Sci. USA, 92 (1995) 1108-1112.
27. Kurose, H. and Lefkowitz, R.J., Differential desensitization and phosphorylation of three cloned and transfected alpha 2-adrenergic receptor subtypes, J. Biol. Chem., 269 (1994) 10093-10099.
28. Liaw, C.W., Lovenberg, T.W., Barry, G., Oltersdorf, T., Grigodiadis, D.E. and De Souza, E.B., Cloning and characterization of the human CRF2 receptor cDNA, Endocrinology 137 (1996) 72-77.
29. Lovenberg, T.W., Liaw, C.W., Grigoriadis, D.E., Clevenger, W., Chalmers, D.T., De Souza, E.B. and Oltersdorf, T. Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain, Proc. Natl. Acad. Sci. USA, 92 (1995) 836-840.
30. Meunier, H., Lefevre, G., Dumont, D. and Labrie, F., CRF stimulates α-MSH secretion and cAMP accumulation in rat pars intermedia cells, Life Sci., 31 (1982) 2129-2135.
31. Munson, P.J. and Rodbard, D., LIGAND: a versatile computerized approach for characterization of ligand binding systems, Anal. Biochem., 297 (1980) 220-229.
32. Owens, M.J. and Nemeroff, C.B., Physiology and pharmacology of corticotropin-releasing factor, Pharmacol. Rev., 43 (1991) 425-473.
33. Perrin, M.H., Donaldson, C.J., Chen, R., Lewis, K.A. and Vale, W.W., Cloning and functional expression of a rat brain corticotropin-releasing factor (CRF) receptor, Endocrinology, 133 (1993) 3058-3061.
34. Perrin, M.H., Donaldson, C.J., Chen, R., Blount, A., Berggren, T., Bilezikjian, L., Sawchenko, P. and Vale, W.W., Identification of a second CRF receptor gene and characterization of a cDNA expressed in heart, Proc. Natl. Acad. Sci. USA, 92 (1995) 2969-2973.
35. Reisine, T. and Hoffman, A., Desensitization of corticotropin-releasing factor receptors, Biochem. Biophys. Res. Commun., 111 (1983) 919-925.
36. Rosendale, B.E., Jarrett, D.B. and Robinson, A.G., Identification of a corticotropin-releasing factor binding protein in the plasma membrane of AtT-20 mouse pituitary tumor cells and its regulation by dexamethasone, Endocrinology, 120 (1987) 2357-2366.
37. Roth, N.S., Campbell, P.T., Caron, M.G., Lefkowitz, R.J. and Lohse, M.J., Comparative rates of desensitization of beta-adrenergic receptors by beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase, Proc. Natl. Acad. Sci. USA, 88 (1991) 6201-6204.
38. Stenzel, P., Kesterson, R., Yeung, W., Cone, R.D., Rittenberg, M.R. and Stenzel-Poore, M.P., Identification of a novel murine receptor for corticotropin-releasing hormone expressed in the heart, Mol. Endocrinol., 9 (1995) 637-645.
39. Strasser, R.H., Cerione, R.A., Codina, J., Caron, M.G. and Lefkowitz, R.J., Homologous desensitization of the beta-adrenergic receptor. Functional integrity of the desensitized receptor from mammalian lung, Mol. Pharmacol., 28 (1985) 237-245.
40. Strasser, R.H. and Lefkowitz, R.J., Homologous desensitization of beta-adrenergic receptor coupled adenylate cyclase. Resensitization by polyethylene glycol treatment, J. Biol. Chem., 260 (1985) 4561-4564.
41. Tizabi, Y. and Aguilera, G., Desensitization of the hypothalamic-pituitary-adrenal axis following prolonged administration of corticotropin-releasing hormone or vasopressin, Neuroendocrinology, 56 (1992) 611-618.
42. Tsagarakis, S. and Grossman, A., Corticotropin-releasing hormone: interactions with the immune system, Neuroimmunomodulation, 1 (1994) 329-334.
43. Vale, W., Spiess, J., Rivier, C. and Rivier, J., Characterization of a 41 residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin, Science, 213 (1981) 1394-1397.
44. Vale, W., Rivier, C., Brown, M.R., Spiess, J., Koob, G., Swanson, L., Bilezikjian, L., Bloom, F. and Rivier, J., Chemical and biological characterization of corticotropin-releasing factor, Recent Prog. Horm. Res., 39 (1983) 245-270.
45. Vamvakopoulos, N.C. and Chrousos, G.P., Hormone regulation of human corticotropin-releasing hormone gene expression: implications for the stress response and immune/inflammatory reaction, Endocrine Rev., 15 (1994) 409-420.
46. Vita, N., Laurent, P., Lefort, S., Chalon, P., Lelias, J.M., Kaghad, M., Le Fur, G., Caput, D. and Ferrara, P., Primary structure and functional expression of mouse pituitary and human brain corticotropin releasing factor receptors, FEBS Lett., 335 (1993) 1-5.
47. Webster, E.L., Tracey, D.E. and De Souza, E.B., Upregulation of interleukin-1 receptors in AtT-20 pituitary tumor cells following treatment with corticotropin-releasing factor, Endocrinology, 129 (1991) 2796-2798.
48. Wynn, P.C., Harwood, J.P., Catt, K.J. and Aguilera, G., Regulation of corticotropin-releasing factor (CRF) receptors in the rat pituitary gland: effects of adrenalectomy on CRF receptors and corticotroph responses, Endocrinology, 116 (1985) 1653-1659.
49. Wynn, P.C., Harwood, J.P., Catt, K.J. and Aguilera, G., Corticotropin-releasing factor (CRF) induces desensitization of the rat pituitary CRF receptor-adenylate cyclase complex, Endocrinology, 122 (1988) 351-358.