Chronic inhibition of intracellular Ca2+ release or protein kinase C activation significantly reduces the development of morphine dependence

European Journal of Pharmacology

Volumn 300, Issue 3, 1996, Pages 173-181

  Fundytus, Marian E ^a,b   Coderre, Terence J ^a,b,c  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Chelerythrine; Inositol 1,4,5 trisphosphate; Metabotropic glutamate receptor; Opioid withdrawal; Protein kinase C; Thapsigargin

Indexed keywords

CALCIUM; CHELERYTHRINE; GLUTAMATE RECEPTOR; METABOTROPIC RECEPTOR; MORPHINE; NALOXONE; PHOSPHATIDYLINOSITOL; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; THAPSIGARGIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DISEASE SEVERITY; DRUG INFUSION; ENZYME ACTIVATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; MORPHINE ADDICTION; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; RAT; SECOND MESSENGER; SUBCUTANEOUS DRUG ADMINISTRATION; WITHDRAWAL SYNDROME;

ALKALOIDS; ANALGESICS, OPIOID; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BENZOPHENANTHRIDINES; CALCIUM-TRANSPORTING ATPASES; ENZYME ACTIVATION; HYDROLYSIS; MALE; MORPHINE; MORPHINE DEPENDENCE; PHENANTHRIDINES; PHOSPHATIDYLINOSITOLS; PROTEIN KINASE C; RATS; SUBSTANCE WITHDRAWAL SYNDROME; THAPSIGARGIN;

EID: 0029937801     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00871-3     Document Type: Article

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