Transcriptional regulation of αB-crystallin in astrocytes: Analysis of HSF and AP1 activation by different types of physiological stress

Journal of Cell Science

Volumn 109, Issue 5, 1996, Pages 1029-1039

  Head, Mark W ^a   Hurwitz, Lina ^a   Goldman, James E ^a  

^a Coll Phys Surgs of Columbia Univ ^*  (United States)

Author keywords

B crystallin; AP1; Astrocyte; Heat shock factor; HSP27; Hypertonicity; Physiological stress; Transcriptional regulation

Indexed keywords

CADMIUM; CRYSTALLIN; HEAT SHOCK PROTEIN; HYPERTONIC SOLUTION; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; ASTROCYTE; CONTROLLED STUDY; GENE INDUCTION; NONHUMAN; OSMOTIC STRESS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN INDUCTION; RAT; STRESS; TRANSCRIPTION REGULATION;

EID: 0029937530     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (73)

1. Andersen, R. D., Taplitz, S. J., Oberbauer, A. M., Calame, K. and Herschman, H. (1990). Metal-dependent binding of a nuclear factor to the rat metallothionine-1 promoter. Nucl. Acids Res. 18, 6049-6055.
2. Aoyama, A., Froehli, E., Schaefer, R. and Klemenz, R. (1993). αB-Crystallin expression in mouse NIH 3T3 fibroblasts: glucocorticoid responsiveness and involvement in thermal protection. Mol. Cell. Biol. 13, 1824-1835.
3. Baler, R., Dahl, G. and Voellmy, R. (1993). Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF 1. Mol. Cell Biol 13, 2486-2496.
4. Cano, E. and Mahadevan, L. C. (1995). Parallel signal processing among mammalian MAPKs. Trends Biochem. Sci. 20, 117-122.
5. Cohen, D. M., Wasserman, J. C. and Gullans, S. R. (1991). Immediate early gene and HSP70 expression in hyperosmotic stress in MDCK cells. Am. J. Physiol. 261, C594-C601.
6. Dasgupta, S., Hohman, T. C. and Carper, D. (1992). Hypertonic stress induces αB-crystallin expression. Exp. Eye Res. 54, 461-470.
7. de Jong, W. W., Leunissen, J. A. M. and Voorter, C. E. M. (1993). Evolution of the α-crystallin/small heat-shock protein family. Mol. Biol. Evol. 10, 103-126.
8. Dubin, R. A., Ally, A. H., Chung, S. and Piatigorsky, J. (1990). Human αB-crystallin gene and preferential promoter function in lens. Genomics 7, 594-601.
9. Duguid, J. R., Rohwer, R. G. and Seed, B. (1988). Isolation of cDNAs of scrapie-modulated RNAs by subtractive hybridization of a cDNA library. Proc. Nat. Acad. Sci. USA 85, 5738-5742.
10. Dwyer, B. E., Nishimura, R. N., De Vellis, J. and Yoshida, T. (1992). Heme oxygenase is a heat shock protein and PEST protein in rat astroglial cells. Glia 5, 300-305.
11. Edington, B. V. and Hightower, L. E. (1989). Induction of a chick small heat shock (stress) protein: evidence for multilevel posttranscriptional regulation. Mol. Cell Biol. 10, 4886-4898.
12. Eddleston, M. and Mucke, L. (1993). Molecular profile of reactive astrocytes: implications for their role in neurologic disease. Neuroscience 54, 15-36.
13. Endoh, M., Pulsinelli, W. A. and Wagner, J. A. (1994). Transient global ischemia induces dynamic changes in the expression of bFGF and the FGF receptor. Mol. Brain Res. 22, 76-88.
14. Engelberg, D., Zandi, E., Parker, C. S. and Karin, M. (1994). The yeast and mammalian ras pathways control transcription of heat shock genes independently of heat shock transcription factor. Mol. Cell Biol. 14, 4929-4937.
15. Frederikse, P. H., Dubin, R. A., Haynes II, J. A. and Piatigorsky, J. (1994). Structure and alternate tissue-preferred transcription initiation of the mouse αB-crystallin/small heat shock protein gene. Nucl. Acids Res. 22, 5686-5694.
16. Frederikse, P. H. and Piatigorsky, J. (1994). Novel and heat inducible binding of HSF to α-crystallin regulatory sequences. Invest. Ophthalmol. Vis. Sci. 35, 2073.
17. Georgopoulos, C. and Welch, W. J. (1993). Role of the major heat shock proteins as molecular chaperones. Annu. Rev. Cell Biol. 9, 601-634.
18. Gopal-Srivastava, R. and Piatigorsky, J. (1994). Identification of a lens-specific regulatory region (LSR) of the murine αB-crystallin gene. Nucl. Acids Res. 22, 1281-1286.
19. Gopal-Srivastava, R., Haynes II, J. I. and Piatigorsky, J. (1995). Regulation of the murine αB-crystallin/small heat shock protein gene in cardiac muscle. Mol. Cell Biol. 12, 7081-7090.
20. Haynes II, J. I., Gopal-Srivastava, R., Frederikse, P. H. and Piatigorsky, J. (1995). Differential use of the regulatory elements of the αB-crystallin enhancer in cultured murine lung (MLg), lens (αTN4-1) and muscle (C2C12) cells. Gene 155, 151-158.
21. Head, M. W., Corbin, E. and Goldman, J. E. (1994). Coordinate and independent regulation of αB-crystallin and HSP27 expression in response to physiological stress. J. Cell Physiol. 159, 41-50.
22. Heuchel, R., Radtke, F., Georgiev, O., Stark, G., Aguet, M. and Schaffner, W. (1994). The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression. EMBOJ. 13, 2870-2875.
23. Hickey, E., Brandon, S. E., Potter, R., Stein, J., Stein, G. and Weber, L. A. (1986). Sequence and organization of genes encoding the 27 kDa heat shock protein. Nucl. Acids Res. 14, 4127-4145.
24. Horwitz, J. (1992). α-Crystallin can function as a molecular chaperone. Proc. Nat. Acad. Sci. USA 89, 10449-10453.
25. Huang, L. E., Caruccio, L., Liu, A. Y.-C. and Chen, K. Y. (1995). Rapid activation of the heat shock transcription factor, HSF1, by hypo-osmotic stress in mammalian cells. Biochem. J. 307, 347-352.
26. 1-adrinergic antagonist. J. Biochem. 117, 1238-1242.
27. Iwaki, A., Iwaki, T., Goldman, J. E. and Liem, R. K. H. (1990). Multiple mRNAs of rat brain α-crystallin B chain result from alternative transcriptional initiation. J. Biol. Chem. 265, 22197-22203.
28. Iwaki, T., Iwaki, A., Miyazono, M. and Goldman, J. E. (1991a). Preferential expression of αB-crystallin in astrocytic elements of neuroectodermal tumors. Cancer 68, 2230-2240.
29. Iwaki, A., Iwaki, T., Sakaki, Y., Liem, R. K. H. and Goldman, J. E. (1991b). Opposite effects of cyclic AMP and cell density on expression of αB-crystallin and glial fibrillary acidic protein in C-6 glioma. In Biological Aspects of Brain Tumors (ed. K. Tabuchi), pp. 396-401. Springer-Verlag, Tokyo.
30. Iwaki, T., Wisniewski, T., Iwaki, A., Corbin, E., Tomokane, N., Tateishi, J. and Goldman, J. E. (1992). Accumulation of αB-crystallin in central nervous system glia and neurons in pathologic conditions. Am. J. Pathol. 140, 345-356.
31. Iwaki, T., Iwaki, A., Tateishi, J., Sakaki, Y. and Goldman, J. E. (1993). αB-crystallin and 27-kd heat shock protein are regulated by stress conditions in the central nervous system and accumulate in Rosenthal fibers. Am. J. Pathol. 143, 487-495.
32. Iwaki, T., Iwaki, A., Tateishi, J. and Goldman, J. E. (1994). Sense and antisense modification of glial αB-crystallin production results in alterations of stress fiber formation and thermoresistence. J. Cell Biol. 125, 1385-1393.
33. +: the implication of a protective role of αB-crystallin accumulation in reactive glia. Brain Res. 673, 47-52.
34. Jakob, U., Gaestel, M., Engel, K. and Buchner, J. (1993). Small heat shock proteins are molecular chaperones. J. Biol. Chem. 268, 1517-1520.
35. Jin, P. and Ringertz, N. R. (1990). Cadmium induces transcription of protooncogenes c-jun and c-myc in rat L6 myoblasts. J. Biol. Chem. 265, 14061-14064.
36. Jurivich, D. A., Sistonen, L., Kroes, R. A. and Morimoto, R. I. (1992). Effect of sodium salicylate on the human heat shock response. Science 255, 1243-1245.
37. Jurivich, D. A., Sistonen, L., Sarge, K. D. and Morimoto, R. I. (1994). Arachidonate is a potent modulator of human heat shock gene transcription. Proc. Nat. Acad. Sci. USA 91, 2280-2284.
38. kaegi, J. H. R. (1991). Overview of metallothionein. Meth. Enzymol. 205, 613-626.
39. Kanei-Ishii, C., Yasukawa, T., Morimoto, R. I. and Ishii, S. ( 1994). c-myb-induced trans-activation mediated by heat shock elements without sequence-specific DNA binding of c-myb. J. Biol. Chem. 269, 15768-15775.
40. Karin, M. (1995). The regulation of API activity by mitogen activated protein kinases. J. Biol. Chem. 270, 16483-16486.
41. Kato, K., Goto, S., Hasegawa, K. and Inaguma, Y. (1993). Coinduction of two low-molecular-weight stress proteins, αB-crystallin and HSP28, by heat or arsenite stress in human glioma cells. J. Biochem. 114, 640-647.
42. Kegel, K. B., Iwaki, A., Iwaki, T. and Goldman, J. E. (1996). αB-crystallin protects glial cells from hypertonic stress. Am. J. Physiol. 270, C903-C909.
43. Klemenz, R., Froehli, E., Steiger, R. H., Schaefer, R. and Aoyama, A. (1991a). αB-crystallin is a small heat shock protein. Proc. Nat. Acad. Sci. USA 88, 3652-3656.
44. Klemenz, R., Froehli, E., Aoyama, A., Huffman, S., Simpson, R., Moritz, R. L. and Schaefer, R. (1991b). αB-Crystallin accumulation is a specific response to Ha-ras and v-mos oncogene expression in mouse NIH 3T3 fibroblasts. Mol. Cell. Biol. 11, 803-812.
45. Kogure, K. and Kato, H. (1993). Altered gene expression in cerebral ischemia. Stroke 24, 2121-2127.
46. +/myoinositol cotransporter, a hypertonicity stress protein. J. Biol. Chem. 267, 6297-6301.
47. Kyriakis, J. M., Banerjee, P., Nikolakaki, T., Dai, T., Rubie, E. A., Ahmad, M. F., Avruch, J. and Woodgett, J. R. (1994). The stress-activated protein kinase subfamily of c-jun kinases. Nature 369, 156-160.
48. Lee, Y. J., Berns, C. M., Galoforo, S., Erdos. G., Cho, J. M. and Corry, P. M. (1995). Differential effects of 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7) on αB-crystallin and hsp70 gene expression in murine cell lines. Biochem. Pharmacol. 50, 1149-1155.
49. Lin, L.-R., Carper, D., Yokoyama, T. and Reddy, V. N. (1993). The effect of hypertonicity on aldose reductase, αB-crystallin, and organic osmolytes in retinal pigmented epithelium. Invest. Ophthalmol. Vis. Sci. 34, 2352-2359.
50. Lis, J. and Wu, C. (1993). Protein traffic on the heat shock promoter: parking, stalling, and trucking along. Cell 74, 1-4.
51. Marcuccilli, C. J. and Miller, R. J. (1994). CNS stress response: too hot to handle? Trends Neurosci. 17, 135-139.
52. Marcuccilli, C. J., Mathur, S. K., Morimoto, R. I. and Miller, R. J. (1996). Regulatory differences in the stress response of hippocampal neurons and glial cells after heat shock. J. Neurosci 16, 478-485.
53. Mehlen, P., Previll, X., Chareyron, P., Briolay, J., Klemenz, R. and Arrigo, A. (1995). Constitutive expression of human hsp27, Drosophila hsp27, or human αB-crystallin confers resistance to TNFα and oxidative stress-induced cytotoxicity in stably transfected murine L929 fibroblasts. J. Immunol. 154, 363-374.
54. Minichiello, L., Remondelli, P., Cigliano, S., Bonatti, S. and Leone, A. (1994). Interactions of nuclear proteins from uninduced, induced and superinduced HeLa cells with the metal regulatory elements MRE3 and 4 of the human metallothionine IIa-encoded gene. Gene 143, 289-294.
55. Morimoto, R. I. (1993). Cells in stress: transcriptional activation of heat shock genes. Science 259, 1409-1410.
56. Mosser, D., Theodorakis, N. G. and Morimoto, R. I. (1988). Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells. Mol. Cell Biol. 8, 4736-4744.
57. Norton, W. T., Aquino, D. A., Hozumi, I., Chiu, F.-C. and Brosnan, C. F. (1992). Quantitative aspects of reactive gliosis: a review. Neurochem. Res. 17, 877-885.
58. Raingeaud, J., Gupta, S., Rogers, J. S., Dickens, M., Han, J., Ulevitch, R. J. and Davis, R. J. (1995). Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270, 7420-7426.
59. Risse, G., Jooss, K., Neuberg, M., Brueller, H.-J. and Mueller, R. (1989) Asymmetrical recognition of the palindromic API binding site (TRE) by fos protein complexes. EMBOJ. 8, 3825-3832.
60. Sambrook, J., Fritsch, E. K. and Maniatis, T. (1989). In Molecular Cloning: A Laboratory Manual, pp. F2. Cold Spring Harbour Laboratory Press, USA.
61. Sarge, K. D., Murphy, S. P. and Morimoto, R. I. (1993). Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization. acquisition of DNA-binding activity and nuclear localization and can occur in the absense of stress. Mol. Cell. Biol. 14, 1392-1407.
62. Sax, C. M. and Piatigorsky, J. (1994). Expression of the α-crystallin/small at shock protein/molecular chaperone genes in the lens and other tissues. Advan. Enzymol. Relat. Areas. Mol. Biol. 69, 155-201.
63. Semenza, G., Roth, P. H., Fang, H.-M and Wang, G. L. (1994). Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor I. J. Biol. Chem. 269, 23757-23763.
64. Sharp, F., Sagar, S. M., Hicks, K., Lowenstein, D. and Hisanaga, K. (1991). C-fos mRNA, fos and fos-related antigen induction by hypertonic saline and stress. J. Neurosci. 11, 2321-2331.
65. Sheikh-Hamad, D., Garcia-Perez, A., Ferraris, J. D., Peters, E. M.. and Burg, M. B. (1994). Induction of gene expression by heat shock versus osmotic stress. Am. J. Physiol. 267, F28-F34.
66. Siebenlist, U., Franzoso, G. and Brown, K. (1994). Structure, regulation and function of NF-κB. Annu. Rev. Cell Biol. 10, 405-455.
67. Srinivasan, A. N. and Bhat, S. P. (1994). Complete structure and expression of the rat αB-crystallin gene. DNA Cell Biol. 13, 651-661.
68. Takenaka, M., Bagnasco, S. M., Preston, A. S., Uchida, S., Yamauchi, A., Kwon, H. M. and Handler, J. S. (1994). The tonicity-sensitive element that mediates increased transcription of the betaine transporter gene in response to hypertonic stress. J. Biol. Chem. 269, 29379-29381.
69. takenaka, M., Bagnasco, S. M., Preston, A. S., Uchida, S., Yamauchi, A., Kwon, H. M. and Handler, J. S. (1995). The canine betaine γ-amino-n-butyric acid transporter gene: diverse mRNA isoforms are regulated by hypertonicity and are expressed in a tissue-specific manner. Proc. Nat. Acad. Sci. USA 92, 1072-1076.
70. 2 induce catalase and metallothionein gene expression in human retinal pigment epithelial cells. Invest. Ophthalmol Vis. Sci. 36, 1271-1279.
71. Warner, H. R. (1994). Superoxide dismutase, aging, and degenerative disease. Free Radical Biol. Med. 17, 249-258.
72. Waskiewicz, A. J. and Cooper, J. A. (1995). Mitogen and stress response pathways: MAP kinase cascade and phosphatase regulation in mammals and yeast. Curr. Opin. Cell Biol. 7, 798-805.
73. Westin, G. and Schaffner, W. (1988). A zinc-responsive factor interacts with a metal-regulated enhancer element (MRE) of the mouse metalothionine-1 gene. EMBOJ. 7, 3763-3770.