메뉴 건너뛰기




Volumn 13, Issue 1, 1996, Pages 16-21

Cytotoxic effects of TGF-α-Pseudomonas exotoxin A fusion protein in human pancreatic carcinoma cells

Author keywords

Epidermal growth factor receptor; Growth inhibition; TP40

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EXOTOXIN; HYBRID PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0029937515     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-199607000-00002     Document Type: Article
Times cited : (11)

References (36)
  • 1
    • 0023626809 scopus 로고
    • Cancer of the pancreas. 50 years of surgery
    • Gudjonsson B. Cancer of the pancreas. 50 years of surgery. Cancer 1987;60:2284-303.
    • (1987) Cancer , vol.60 , pp. 2284-2303
    • Gudjonsson, B.1
  • 3
    • 0026462778 scopus 로고
    • Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha
    • Korc M, Chandrasekar B, Yamanaka Y, Friess H, Büchler M, Beger HG. Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha. J Clin Invest 1992; 90:1352-60.
    • (1992) J Clin Invest , vol.90 , pp. 1352-1360
    • Korc, M.1    Chandrasekar, B.2    Yamanaka, Y.3    Friess, H.4    Büchler, M.5    Beger, H.G.6
  • 5
    • 0028101982 scopus 로고
    • Induction and expression of amphiregulin in human pancreatic cancer
    • Ebert M, Yokoyama M, Kobrin MS, et al. Induction and expression of amphiregulin in human pancreatic cancer. Cancer Res 1994;54:3959-62.
    • (1994) Cancer Res , vol.54 , pp. 3959-3962
    • Ebert, M.1    Yokoyama, M.2    Kobrin, M.S.3
  • 6
    • 0027293748 scopus 로고
    • Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness
    • Yamanaka Y, Friess H, Kobrin MS, Büchler M, Beger HG, Korc M. Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness. Anticancer Res 1993;13: 565-9.
    • (1993) Anticancer Res , vol.13 , pp. 565-569
    • Yamanaka, Y.1    Friess, H.2    Kobrin, M.S.3    Büchler, M.4    Beger, H.G.5    Korc, M.6
  • 7
    • 0028918095 scopus 로고
    • Amphiregulin is a potent nitrogen in human pancreatic cancer cells: Correlation with patient survival
    • Munehiro Y, Ebert M, Funatomi H, et al. Amphiregulin is a potent nitrogen in human pancreatic cancer cells: correlation with patient survival. Int J Oncol 1995;6:625-31.
    • (1995) Int J Oncol , vol.6 , pp. 625-631
    • Munehiro, Y.1    Ebert, M.2    Funatomi, H.3
  • 8
    • 0021223821 scopus 로고
    • Cloning, nucleotide sequence and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa
    • Gray GL, Smith DL, Baldridge JS, et al. Cloning, nucleotide sequence and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa. Proc Natl Acad Sci USA 1984;81:2645-9.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 2645-2649
    • Gray, G.L.1    Smith, D.L.2    Baldridge, J.S.3
  • 9
    • 0025185583 scopus 로고
    • Structure, function, and regulation of Pseudomonas aeruginosa exotoxin A
    • Wick MJ, Frank DW, Storey DG, Iglewski BH. Structure, function, and regulation of Pseudomonas aeruginosa exotoxin A. Annu Rev Micro 1990;44:335-63.
    • (1990) Annu Rev Micro , vol.44 , pp. 335-363
    • Wick, M.J.1    Frank, D.W.2    Storey, D.G.3    Iglewski, B.H.4
  • 10
    • 0022879075 scopus 로고
    • Pseudomonas exotoxin A: Membrane binding, insertion and traversal
    • Farahbakhsh ZT, Baldwin RL, Wisnieski BJ. Pseudomonas exotoxin A: membrane binding, insertion and traversal. J Biol Chem 1986;261:11404-8.
    • (1986) J Biol Chem , vol.261 , pp. 11404-11408
    • Farahbakhsh, Z.T.1    Baldwin, R.L.2    Wisnieski, B.J.3
  • 11
    • 0024433513 scopus 로고
    • Pseudomonas exotoxin: Chimeric toxins
    • Pastan I, FitzGerald DJ. Pseudomonas exotoxin: chimeric toxins. J Biol Chem 1989;264:15157-60.
    • (1989) J Biol Chem , vol.264 , pp. 15157-15160
    • Pastan, I.1    FitzGerald, D.J.2
  • 12
    • 0023888286 scopus 로고
    • Activity of immunotoxins constructed with modified Pseudomonas exotoxin A lacking the cell recognition domain
    • Kondo T, FitzGerald DJ, Chaudhary VK, Adhya S, Pastan I. Activity of immunotoxins constructed with modified Pseudomonas exotoxin A lacking the cell recognition domain. J Biol Chem 1988;263:9470-5.
    • (1988) J Biol Chem , vol.263 , pp. 9470-9475
    • Kondo, T.1    FitzGerald, D.J.2    Chaudhary, V.K.3    Adhya, S.4    Pastan, I.5
  • 13
    • 0025297182 scopus 로고
    • Transforming growth faclor-α-Pseudomonas exotoxin fusion protein prolongs survival of nude mice bearing xenografts
    • Heimbrook DC, Stirdivant SM, Ahern JD, et al. Transforming growth faclor-α-Pseudomonas exotoxin fusion protein prolongs survival of nude mice bearing xenografts. Proc Natl Acad Sci USA 1990;87:4697-701.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4697-4701
    • Heimbrook, D.C.1    Stirdivant, S.M.2    Ahern, J.D.3
  • 14
    • 0023368762 scopus 로고
    • Activity of a recombinant fusion protein between transforming growth factor type a and Pseudomonas toxin
    • Chaudhary VK, FitzGerald DJ, Adhya S, Pastan I. Activity of a recombinant fusion protein between transforming growth factor type a and Pseudomonas toxin. Proc Natl Acad Sci USA 1987;84:4538-42.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 4538-4542
    • Chaudhary, V.K.1    FitzGerald, D.J.2    Adhya, S.3    Pastan, I.4
  • 16
    • 0343620855 scopus 로고
    • Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer
    • Korc M, Meltzer P, Trent J. Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer. Proc Natl Acad Sci USA 1986;83:5141-4.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5141-5144
    • Korc, M.1    Meltzer, P.2    Trent, J.3
  • 17
    • 0026343922 scopus 로고
    • Differential binding and biological activities of epidermal growth factor and transforming growth factor a in a human pancreatic cancer cell line
    • Korc M, Chandrasekar B, Shah GN. Differential binding and biological activities of epidermal growth factor and transforming growth factor a in a human pancreatic cancer cell line. Cancer Res 1991;51:6243-9.
    • (1991) Cancer Res , vol.51 , pp. 6243-6249
    • Korc, M.1    Chandrasekar, B.2    Shah, G.N.3
  • 18
    • 0028043510 scopus 로고
    • A variant epidermal growth factor receptor exhibits altered type a transforming growth factor binding and transmembrane signaling
    • Moriai T, Kobrin MS, Hope C, Speck L, Korc M. A variant epidermal growth factor receptor exhibits altered type a transforming growth factor binding and transmembrane signaling. Proc Natl Acad Sci USA 1994;91:10217-21.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10217-10221
    • Moriai, T.1    Kobrin, M.S.2    Hope, C.3    Speck, L.4    Korc, M.5
  • 19
    • 0023277545 scopus 로고
    • Single-step RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-9.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 20
    • 0021344768 scopus 로고
    • Inducible expression of amplified human beta interferon genes in CHO cells
    • McCormick F, Trahey M, Innis M, Dieckmann B, Ringold G. Inducible expression of amplified human beta interferon genes in CHO cells. Mol Cell Biol 1984;4:166-72.
    • (1984) Mol Cell Biol , vol.4 , pp. 166-172
    • McCormick, F.1    Trahey, M.2    Innis, M.3    Dieckmann, B.4    Ringold, G.5
  • 21
    • 0024435665 scopus 로고
    • Attenuated processing of epidermal growth factor in the face of marked degradation of transforming growth factor-α
    • Korc M, Finman JE. Attenuated processing of epidermal growth factor in the face of marked degradation of transforming growth factor-α. J Biol Chem 1989;264:14990-9.
    • (1989) J Biol Chem , vol.264 , pp. 14990-14999
    • Korc, M.1    Finman, J.E.2
  • 22
    • 84969001783 scopus 로고
    • The attractions of proteins for small molecules and ions
    • Scatchard G. The attractions of proteins for small molecules and ions. Ann NY Acad Sci 1949;5:660-72.
    • (1949) Ann NY Acad Sci , vol.5 , pp. 660-672
    • Scatchard, G.1
  • 23
    • 0019061918 scopus 로고
    • Ligand: A versatile computerized approach for characterization of ligand-binding systems
    • Munson PJ, Robard D. Ligand: a versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 1980;107:220-39.
    • (1980) Anal Biochem , vol.107 , pp. 220-239
    • Munson, P.J.1    Robard, D.2
  • 24
    • 0021287698 scopus 로고
    • Rapid colorimetric assay for cell viability: Application to the quantitation of cytotoxic and growth inhibitory lymphokines
    • Green LM, Reade JL, Ware CF. Rapid colorimetric assay for cell viability: application to the quantitation of cytotoxic and growth inhibitory lymphokines. J Immunol Methods 1984;70:257-68.
    • (1984) J Immunol Methods , vol.70 , pp. 257-268
    • Green, L.M.1    Reade, J.L.2    Ware, C.F.3
  • 25
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mossmann PB, Young LL. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:49-53.
    • (1983) J Immunol Methods , vol.65 , pp. 49-53
    • Mossmann, P.B.1    Young, L.L.2
  • 26
    • 0023019005 scopus 로고
    • Use of MTT colorimetric assay to measure cell activation
    • Gerlier D, Thomasset N. Use of MTT colorimetric assay to measure cell activation. J Immunol Methods 1986;94:57-63.
    • (1986) J Immunol Methods , vol.94 , pp. 57-63
    • Gerlier, D.1    Thomasset, N.2
  • 27
    • 0025742806 scopus 로고
    • Antitumor activity of a transforming growth factor α-Pseudomonas exotoxin fusion protein (TP40)
    • Pai LH, Gallo MG, FitzGerald DJ, Pastan I. Antitumor activity of a transforming growth factor α-Pseudomonas exotoxin fusion protein (TP40). Cancer Res 1991;51:2808-12.
    • (1991) Cancer Res , vol.51 , pp. 2808-2812
    • Pai, L.H.1    Gallo, M.G.2    FitzGerald, D.J.3    Pastan, I.4
  • 29
    • 0023949462 scopus 로고
    • Amplified and overexpressed epidermal growth factor receptor gene in uncultured primary human breast carcinoma
    • Ro J, North S, Gallick GE, Hortobagyi GN, Gutterman JU, Blick M. Amplified and overexpressed epidermal growth factor receptor gene in uncultured primary human breast carcinoma. Cancer Res 1987;48:161-4.
    • (1987) Cancer Res , vol.48 , pp. 161-164
    • Ro, J.1    North, S.2    Gallick, G.E.3    Hortobagyi, G.N.4    Gutterman, J.U.5    Blick, M.6
  • 30
    • 84920241849 scopus 로고
    • Epidermal-growth-factor receptors in human bladder cancer: Comparison of invasive and superficial tumors
    • Neal DE, Bennet MK, Hall RR, et al. Epidermal-growth-factor receptors in human bladder cancer: comparison of invasive and superficial tumors. Lancet 1985;1:366-8.
    • (1985) Lancet , vol.1 , pp. 366-368
    • Neal, D.E.1    Bennet, M.K.2    Hall, R.R.3
  • 31
    • 0023877293 scopus 로고
    • Epidermal growth factor in the normal and neoplastic kidney and bladder
    • Lau JL, Fowler JE Jr, Ghosh L. Epidermal growth factor in the normal and neoplastic kidney and bladder. J Urol 1988; 139:170-5.
    • (1988) J Urol , vol.139 , pp. 170-175
    • Lau, J.L.1    Fowler Jr., J.E.2    Ghosh, L.3
  • 32
    • 0024510886 scopus 로고
    • Characterization of epidermal growth factor receptor in primary human non-small cell lung cancer
    • Veale D, Kerr N, Gibson GJ, Harris AL. Characterization of epidermal growth factor receptor in primary human non-small cell lung cancer. Cancer Res 1989;49:1313-7.
    • (1989) Cancer Res , vol.49 , pp. 1313-1317
    • Veale, D.1    Kerr, N.2    Gibson, G.J.3    Harris, A.L.4
  • 33
    • 0024956403 scopus 로고
    • Role of transforming growth factor-α in human prostate cancer cell growth
    • Steck PA, Lee P, Hung M-C, Gelmann EP. Role of transforming growth factor-α in human prostate cancer cell growth. Prostate 1989;15:1-12.
    • (1989) Prostate , vol.15 , pp. 1-12
    • Steck, P.A.1    Lee, P.2    Hung, M.-C.3    Gelmann, E.P.4
  • 34
    • 0025317908 scopus 로고
    • 6]-leutinizing hormone-releasing hormone and epidermal growth factor in human endometrial carcinoma
    • 6]-leutinizing hormone-releasing hormone and epidermal growth factor in human endometrial carcinoma. Cancer Res 1990;50:1841-6.
    • (1990) Cancer Res , vol.50 , pp. 1841-1846
    • Srkalovic, G.1    Wittliff, J.L.2    Schally, A.V.3
  • 35
    • 0023449818 scopus 로고
    • Production of transforming growth factor a in human pancreatic cancer cells: Evidence for a superagonist autocrine cycle
    • Smith JJ, Derynck R, Korc M. Production of transforming growth factor a in human pancreatic cancer cells: evidence for a superagonist autocrine cycle. Proc Natl Acad Sci USA 1987;84:7567-70.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7567-7570
    • Smith, J.J.1    Derynck, R.2    Korc, M.3
  • 36
    • 0025761039 scopus 로고
    • Cytotoxic effects of a recombinant chimeric toxin on rapidly proliferating vascular smooth muscle cells
    • Epstein SE, Siegall CB, Biro S, Fu M, FitzGerald DJ, Pastan I. Cytotoxic effects of a recombinant chimeric toxin on rapidly proliferating vascular smooth muscle cells. Circulation 1991;84:778-87.
    • (1991) Circulation , vol.84 , pp. 778-787
    • Epstein, S.E.1    Siegall, C.B.2    Biro, S.3    Fu, M.4    FitzGerald, D.J.5    Pastan, I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.