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Volumn 12, Issue 2, 1996, Pages 147-152

Pilot Study of Topical Trifluridine for the Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients with AIDS (ACTG 172)

(15)  Kessler, H A a   Hurwitz, S b   Farthing, C c   Benson, C A a   Feinberg, J d   Kuritzkes, D R e   Bailey, T C f   Safrin, S g   Steigbigel, R T h   Cheeseman, S H i   McKinley, Hug F j   Wettlaufer, B b   Owens, S k   Nevin, T l   Korvick, J A l  


Author keywords

Acyclovir; Herpes simplex; HIV; Resistance; Topical; Trifluridine

Indexed keywords

ACICLOVIR; FOSCARNET; TRIFLURIDINE;

EID: 0029937485     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199606010-00007     Document Type: Article
Times cited : (44)

References (34)
  • 1
    • 0011864618 scopus 로고
    • Herpesvirus infections in the acquired immune deficiency syndrome
    • Quinnan GV, Masur H, Rook AH, et al. Herpesvirus infections in the acquired immune deficiency syndrome. JAMA 1984;252:72-7.
    • (1984) JAMA , vol.252 , pp. 72-77
    • Quinnan, G.V.1    Masur, H.2    Rook, A.H.3
  • 2
    • 0015290007 scopus 로고
    • Extensive skin manifestations of herpesvirus infection in an acute leukemic child
    • Nishimura K, Nagamoto A, Igarashi M. Extensive skin manifestations of herpesvirus infection in an acute leukemic child. Pediatrics 1972;49:294-7.
    • (1972) Pediatrics , vol.49 , pp. 294-297
    • Nishimura, K.1    Nagamoto, A.2    Igarashi, M.3
  • 3
    • 0015266281 scopus 로고
    • Herpes simplex infections in hematologic malignancies
    • Muller SA, Hermann EC, Winkelmann RK. Herpes simplex infections in hematologic malignancies. Am J Med 1972;52:102-14.
    • (1972) Am J Med , vol.52 , pp. 102-114
    • Muller, S.A.1    Hermann, E.C.2    Winkelmann, R.K.3
  • 4
    • 0015937546 scopus 로고
    • Infection with herpes-simplex viruses 1 and 2
    • Nahmias AJ, Roizman B. Infection with herpes-simplex viruses 1 and 2. N Engl J Med 1973;289:667-74,719-25,781-9.
    • (1973) N Engl J Med , vol.289 , pp. 667-674
    • Nahmias, A.J.1    Roizman, B.2
  • 5
    • 0017653042 scopus 로고
    • Atypical herpes simplex virus hominis type 2 infection in uremic patients receiving immunosuppressive therapy
    • Stone WJ, Scowden EB, Spannuth CL, Lowry SP, Alford RH. Atypical herpes simplex virus hominis type 2 infection in uremic patients receiving immunosuppressive therapy. Am J Med 1977;6:511-6.
    • (1977) Am J Med , vol.6 , pp. 511-516
    • Stone, W.J.1    Scowden, E.B.2    Spannuth, C.L.3    Lowry, S.P.4    Alford, R.H.5
  • 6
    • 0018935309 scopus 로고
    • Infection with herpes simplex virus and cell-mediated immunity after marrow transplant
    • Meyers JD, Flournoy N, Thomas ED. Infection with herpes simplex virus and cell-mediated immunity after marrow transplant. J Infect Dis 1980;142:338-46.
    • (1980) J Infect Dis , vol.142 , pp. 338-346
    • Meyers, J.D.1    Flournoy, N.2    Thomas, E.D.3
  • 7
    • 0019918353 scopus 로고
    • Mucocutaneous herpes simplex virus infections in immunocompromised patients: A model for evaluation of topical antiviral agents
    • Whitley RJ, Barton N, Collins E, Whelchel J, Diethelm AG. Mucocutaneous herpes simplex virus infections in immunocompromised patients: a model for evaluation of topical antiviral agents. Am J Med 1982;73:236-40.
    • (1982) Am J Med , vol.73 , pp. 236-240
    • Whitley, R.J.1    Barton, N.2    Collins, E.3    Whelchel, J.4    Diethelm, A.G.5
  • 8
    • 0019840829 scopus 로고
    • Severe acquired immunodeficiency in male homosexuals, manifested by chronic perianal ulcerative herpes simplex lesions
    • Siegal FP, Lopez C, Hammer GS, et al. Severe acquired immunodeficiency in male homosexuals, manifested by chronic perianal ulcerative herpes simplex lesions. N Engl J Med 1981;305:1439-44.
    • (1981) N Engl J Med , vol.305 , pp. 1439-1444
    • Siegal, F.P.1    Lopez, C.2    Hammer, G.S.3
  • 9
    • 0023742336 scopus 로고
    • Severe, progressive herpetic whitlow caused by an acyclovir-resistant virus in a patient with AIDS
    • Norris SA, Kessler HA, Fife KH. Severe, progressive herpetic whitlow caused by an acyclovir-resistant virus in a patient with AIDS. J Infect Dis 1988;157:209-10.
    • (1988) J Infect Dis , vol.157 , pp. 209-210
    • Norris, S.A.1    Kessler, H.A.2    Fife, K.H.3
  • 10
    • 0024510412 scopus 로고
    • Foscarnet therapy for severe acyclovir-resistant herpes simplex virus type-2 infections in patients with the acquired immunodeficiency syndrome (AIDS): An uncontrolled trial
    • Erlich KS, Jacobson MA, Koehler JE, et al. Foscarnet therapy for severe acyclovir-resistant herpes simplex virus type-2 infections in patients with the acquired immunodeficiency syndrome (AIDS): an uncontrolled trial. Ann Intern Med 1989;110:710-3.
    • (1989) Ann Intern Med , vol.110 , pp. 710-713
    • Erlich, K.S.1    Jacobson, M.A.2    Koehler, J.E.3
  • 11
    • 0024476921 scopus 로고
    • Successful treatment with foscarnet of an acyclovir-resistant mucocutaneous infection with herpes simplex virus in a patient with acquired immunodeficiency syndrome
    • Chatis PA, Miller CH, Schrager LE, Crumpacker CS. Successful treatment with foscarnet of an acyclovir-resistant mucocutaneous infection with herpes simplex virus in a patient with acquired immunodeficiency syndrome. N Engl J Med 1989;320:297-300.
    • (1989) N Engl J Med , vol.320 , pp. 297-300
    • Chatis, P.A.1    Miller, C.H.2    Schrager, L.E.3    Crumpacker, C.S.4
  • 12
    • 0024672245 scopus 로고
    • Mucocutaneous dissemination of acyclovir-resistant herpes simplex virus in a patient with AIDS
    • Marks GL, Nolan PE, Erlich KS, Ellis MN. Mucocutaneous dissemination of acyclovir-resistant herpes simplex virus in a patient with AIDS. Rev Infect Dis 1989;11:474-6.
    • (1989) Rev Infect Dis , vol.11 , pp. 474-476
    • Marks, G.L.1    Nolan, P.E.2    Erlich, K.S.3    Ellis, M.N.4
  • 13
    • 0025268266 scopus 로고
    • Treatment of resistant herpes simplex virus with continuous-infusion acyclovir
    • Engel JP, Englund JA, Fletcher CV, Hill EL. Treatment of resistant herpes simplex virus with continuous-infusion acyclovir. JAMA 1990;263:1662-4.
    • (1990) JAMA , vol.263 , pp. 1662-1664
    • Engel, J.P.1    Englund, J.A.2    Fletcher, C.V.3    Hill, E.L.4
  • 14
    • 0025106038 scopus 로고
    • Altered sensitivity to antiviral drugs of herpes simplex virus isolates from a patient with the acquired immunodeficiency syndrome
    • Birch CJ, Tachedjian G, Doherty RR, Hayes K, Gust ID. Altered sensitivity to antiviral drugs of herpes simplex virus isolates from a patient with the acquired immunodeficiency syndrome. J Infect Dis 1990;162:731-4.
    • (1990) J Infect Dis , vol.162 , pp. 731-734
    • Birch, C.J.1    Tachedjian, G.2    Doherty, R.R.3    Hayes, K.4    Gust, I.D.5
  • 15
    • 0025896084 scopus 로고
    • A controlled trial comparing foscarnet with vidarabine for acyclovir-resistant mucocutaneous herpes simplex in the acquired immunodeficiency syndrome
    • Safrin S, Crumpacker CS, Chatis P, et al. A controlled trial comparing foscarnet with vidarabine for acyclovir-resistant mucocutaneous herpes simplex in the acquired immunodeficiency syndrome. N Engl J Med 1991;325:551-5.
    • (1991) N Engl J Med , vol.325 , pp. 551-555
    • Safrin, S.1    Crumpacker, C.S.2    Chatis, P.3
  • 16
    • 0019425636 scopus 로고
    • Acyclovir therapy for mucocutaneous herpes simplex infections in immunocompromised patients
    • Mitchell CD, Bean B, Gentry SR, Groth KE, Boen JR, Balfour HH. Acyclovir therapy for mucocutaneous herpes simplex infections in immunocompromised patients. Lancet 1981;2:1389-92.
    • (1981) Lancet , vol.2 , pp. 1389-1392
    • Mitchell, C.D.1    Bean, B.2    Gentry, S.R.3    Groth, K.E.4    Boen, J.R.5    Balfour, H.H.6
  • 17
  • 18
    • 0021246992 scopus 로고
    • Oral acyclovir to suppress recurring herpes simplex virus infections in immunodeficient patients
    • Straus SE, Seidlin M, Takiff H, Jacobs D, Bowen D, Smith HA. Oral acyclovir to suppress recurring herpes simplex virus infections in immunodeficient patients. Ann Intern Med 1984;100:522-4.
    • (1984) Ann Intern Med , vol.100 , pp. 522-524
    • Straus, S.E.1    Seidlin, M.2    Takiff, H.3    Jacobs, D.4    Bowen, D.5    Smith, H.A.6
  • 19
    • 0027117028 scopus 로고
    • Acyclovir: A decade later
    • Gnann J, Whitley RJ. Acyclovir: a decade later. N Engl J Med 1992;327:782-9.
    • (1992) N Engl J Med , vol.327 , pp. 782-789
    • Gnann, J.1    Whitley, R.J.2
  • 21
    • 0026063125 scopus 로고
    • In vitro and in vivo characterization of herpes simplex virus clinical isolates recovered from patients infected with human immunodeficiency virus
    • Hill EL, Hunter GA, Ellis MN. In vitro and in vivo characterization of herpes simplex virus clinical isolates recovered from patients infected with human immunodeficiency virus. Antimicrob Agents Chemother 1991;35:2322-8.
    • (1991) Antimicrob Agents Chemother , vol.35 , pp. 2322-2328
    • Hill, E.L.1    Hunter, G.A.2    Ellis, M.N.3
  • 22
    • 0028214014 scopus 로고
    • Correlation between response to acyclovir and foscarnet therapy and in vitro susceptibility result for isolates of herpes simplex virus from human immunodeficiency virus-infected patients
    • Safrin S, Elbeik T, Phan L, et al. Correlation between response to acyclovir and foscarnet therapy and in vitro susceptibility result for isolates of herpes simplex virus from human immunodeficiency virus-infected patients. Antimicrob Agents Chemother 1994;38:1246-50.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 1246-1250
    • Safrin, S.1    Elbeik, T.2    Phan, L.3
  • 23
    • 0020700645 scopus 로고
    • Resistance of herpes simplex to acyclovir
    • Balfour HH. Resistance of herpes simplex to acyclovir. Ann Intern Med 1983;98:404-6.
    • (1983) Ann Intern Med , vol.98 , pp. 404-406
    • Balfour, H.H.1
  • 24
    • 0019309198 scopus 로고
    • Isolation and characterization of acyclovir-resistant mutants of herpes simplex virus
    • Field H, Darby G, Wildy P. Isolation and characterization of acyclovir-resistant mutants of herpes simplex virus. J Gen Virol 1980;49:115-24.
    • (1980) J Gen Virol , vol.49 , pp. 115-124
    • Field, H.1    Darby, G.2    Wildy, P.3
  • 25
    • 0019350295 scopus 로고
    • Altered substrate specificity of herpes simplex virus thymidine kinase confers acyclovir-resistance
    • Darby G, Field HJ. Altered substrate specificity of herpes simplex virus thymidine kinase confers acyclovir-resistance. Nature 1981;289:81-3.
    • (1981) Nature , vol.289 , pp. 81-83
    • Darby, G.1    Field, H.J.2
  • 26
    • 0023254664 scopus 로고
    • Clinical isolate of herpes simplex type 2 that induces a thymidine kinase with altered substrate specificity
    • Ellis MM, Keller DM, Fyfe JL, et al. Clinical isolate of herpes simplex type 2 that induces a thymidine kinase with altered substrate specificity. Antimicrob Agents Chemother 1987;31:1117-25.
    • (1987) Antimicrob Agents Chemother , vol.31 , pp. 1117-1125
    • Ellis, M.M.1    Keller, D.M.2    Fyfe, J.L.3
  • 28
    • 0025281098 scopus 로고
    • Foscarnet therapy for acyclovir-resistant mucocutaneous herpes simplex virus infection in 26 AIDS patients: Preliminary data
    • Safrin S, Assaykeen T, Follansbee SE, Mills J. Foscarnet therapy for acyclovir-resistant mucocutaneous herpes simplex virus infection in 26 AIDS patients: preliminary data. J Infect Dis 1990;161:1078-84.
    • (1990) J Infect Dis , vol.161 , pp. 1078-1084
    • Safrin, S.1    Assaykeen, T.2    Follansbee, S.E.3    Mills, J.4
  • 30
    • 0026653399 scopus 로고
    • Clinical effects and in vitro studies of trifluorothymidine combined with interferon-alpha for treatment of drug-resistant and -sensitive herpes simplex virus infections
    • Birch CJ, Tyssen DP, Tachedjian G, et al. Clinical effects and in vitro studies of trifluorothymidine combined with interferon-alpha for treatment of drug-resistant and -sensitive herpes simplex virus infections. J Infect Dis 1992;166:108-12.
    • (1992) J Infect Dis , vol.166 , pp. 108-112
    • Birch, C.J.1    Tyssen, D.P.2    Tachedjian, G.3
  • 31
    • 0020326471 scopus 로고
    • Trifluridine: A review of its antiviral activity and therapeutic use in the topical treatment of viral eye infections
    • Carmine AA, Brogden RN, Heel RC, Speight TM, Avery GS. Trifluridine: a review of its antiviral activity and therapeutic use in the topical treatment of viral eye infections. Drug Eval 1982;23:329-53.
    • (1982) Drug Eval , vol.23 , pp. 329-353
    • Carmine, A.A.1    Brogden, R.N.2    Heel, R.C.3    Speight, T.M.4    Avery, G.S.5
  • 32
    • 0021195611 scopus 로고
    • Infections caused by herpes simplex virus in the immunocompromised host: Natural history and topical acyclovir therapy
    • Whitley RJ, Levin M, Barton N, et al. Infections caused by herpes simplex virus in the immunocompromised host: natural history and topical acyclovir therapy. J Infect Dis 1989;150:323-9.
    • (1989) J Infect Dis , vol.150 , pp. 323-329
    • Whitley, R.J.1    Levin, M.2    Barton, N.3
  • 33
    • 0029092805 scopus 로고
    • Herpes simplex virus resistance to acyclovir: Clinical relevance
    • Pottage JC, Kessler HA. Herpes simplex virus resistance to acyclovir: clinical relevance. Infect Agents Dis 1995;4:115-24.
    • (1995) Infect Agents Dis , vol.4 , pp. 115-124
    • Pottage, J.C.1    Kessler, H.A.2
  • 34
    • 0021690095 scopus 로고
    • Effect of azone and propylene glycol on penetration of trifluorothymidine through skin and efficacy of different topical formulations against cutaneous herpes simplex virus infections in guinea pigs
    • Spruance SL, McKeough M, Sugibayashi K, Robertson F, Gaede P, Clark DS. Effect of azone and propylene glycol on penetration of trifluorothymidine through skin and efficacy of different topical formulations against cutaneous herpes simplex virus infections in guinea pigs. Antimicrob Agents Chemother 1984;26:819-23.
    • (1984) Antimicrob Agents Chemother , vol.26 , pp. 819-823
    • Spruance, S.L.1    McKeough, M.2    Sugibayashi, K.3    Robertson, F.4    Gaede, P.5    Clark, D.S.6


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