Can early asthma be confirmed by laboratory tests?

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 51, Issue 4, 1996, Pages 226-231

  Metso, T ^a   Kilpio K ^a   Bjorksten F ^a   Kiviranta, K ^a   Haahtela, T ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

bronchial hyperreactivity; eosinophil; eosinophil cationic protein (ECP); eosinophil protein X (EPX); histamine challenge; myeloperoxidase; peak expiratory flow; sputum

Indexed keywords

EOSINOPHIL CATIONIC PROTEIN;

ADULT; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CLINICAL ARTICLE; CLINICAL TRIAL; DIAGNOSTIC VALUE; FEMALE; HUMAN; LABORATORY TEST; MALE; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL; PROVOCATION TEST; SPUTUM ANALYSIS;

EID: 0029937345     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1398-9995.1996.tb04597.x     Document Type: Article

References (17)

1. Laitinen LA, Laitinen A, Haahtela T. Airway mucosal inflammation even in patients with newly diagnosed asthma. Am Rev Respir Dis 1993;147:697-704.
2. Venge P. Serum measurements of eosinophil cationic protein (ECP) in bronchial asthma. Clin Exp Allergy 1993;23 Suppl:3-7.
3. Bousquet J, Chanez P, Lacosta JY, et al. Indirect evidence of bronchial inflammation assessed by titration of mediators released by inflammatory cells in BAL fluid. J Allergy Clin Immunol 1991;88:649-60.
4. Virchow J-C, Hölscher U, Virchow C. Sputum ECP levels correlate with parameters of airflow obstruction. Am Rev Respir Dis 1992;146:604-6.
5. Kallenbach J, Baynes R, Fine B, Dajee D, Bezwoda W. Persistent neutrophil activation in mild asthma. J Allergy Clin Immunol 1992;90:272-4.
6. Lee TH. Mediators of bronchial responsiveness. In: Clark TJH, Godfrey S. Lee TH, editors. Asthma. London: Chapman & Hall, 1992:162-81.
7. Ahlstedt S, Enander I, Peterson C, Rak S, Venge P. Clinical assessment of the inflammatory component of asthma with emphasis on the eosinophils. Pharm Med 1992;6:99-111.
8. Fahy JV, Liu J, Wong H, Boushley HA. Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 1993;147: 1126-31.
9. Pin I, Gibson PG, Kolendowicz R, et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992;47:25-9.
10. Sovijärvi A, Malmberg P, Reinikainen K, Rytilä P, Poppius H. A rapid dosimetric method with controlled tidal breathing for histamine challenge. Chest 1993;104:164-70.
11. Drebor S. Skin tests used in type I allergy testing. Position paper. Allergy 1989;44 Suppl 10:52-9.
12. Hansel FK. Allergy in relation to otolaryngology. St Paul and Minneapolis, MN: Bruce, 1949.
13. Stretton TB, Lee HY. Asthma in the elderly. BMJ 1972; 4:93-5.
14. Chodosh S. Examination of sputum cells. N Engl J Med 1970;282:854-8.
15. Bentley AM, Menz G, Storz C, et al. Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Am Rev Respir Dis 1992;146:500-6.
16. Walker C, Bode E, Boer L, Hansel TT, Blaser K, Virchow JC. Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am Rev Respir Dis 1992;146:109-15.
17. Nunn AJ, Gregg I. New regression equations for predicting peak expiratory flow in adults. BMJ 1989;298:1068-70.