Expression of estrogen receptor-like immunoreactivity by different subgroups of basal forebrain cholinergic neurons in gonadectomized male and female rats

Brain Research

Volumn 720, Issue 1-2, 1996, Pages 61-68

  Gibbs, Robert B ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Alzheimer's disease; Choline acetyltransferase; Diagonal band of Broca; Nucleus basalis; Septum; Striatum

Indexed keywords

CHOLINE ACETYLTRANSFERASE; ESTROGEN RECEPTOR;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; FEMALE; FOREBRAIN; GENE EXPRESSION; GONADECTOMY; IMMUNOCYTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0029936993     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00106-0     Document Type: Article

References (14)

1. Berghorn, K.A., Bonnett, J.H. and Hoffman, G.E., cFos immuno-reactivity is enhanced with biotin amplification, J. Histochem. Cytochem., 42 (1994) 1635-1642.
2. Gibbs, R.B., Estrogen and nerve growth factor-related systems in brain: effects on basal forebrain cholinergic neurons and implications for learning and memory processes and aging. In V.N. Luine and C.F. Harding (Eds.), Hormonal Restructuring of the Adult Brain: Basic and Clinical Perspectives, 743, New York Acad. Sci., New York, 1994, pp. 165-199.
3. Gibbs, R.B., Fluctuations in relative levels of choline acetyltransferase mRNA in different regions of the rat basal forebrain across the estrus cycle: effects of estrogen and progesterone, J. Neurosci., 16 (1996) 1049-1055.
4. NGFR and ChAT expression in the medial septum and diagonal band of Broca, Exp. Neurol., 116 (1992) 23-39.
5. Gibbs, R.B., Wu, D.-H., Hersh, L. and Pfaff, D.W., Effects of estrogen on relative levels of ChAT, trkA, and NGF mRNAs in the rat forebrain and hippocampal formation, Exp. Neurol., 129 (1994) 70-80.
6. Henderson, V.W., Paganini-Hill, A., Emanuel, C.K., Dunn, M.E. and Buckwalter, J.G., Estrogen replacement therapy in older women. Comparisons between Alzheimer's disease cases and nondemented control subjects, Arch. Neurol., 51 (1994) 896-900.
7. Honjo, H., Tanaka, K., Kashiwagi, T., Urabe, M., Hayashi, O.M. and Hayashi, K., Senile dementia-Alzheimer's type and estrogen, Horm. Metab. Res., 27 (1994) 204-207.
8. Luine, V.N., Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats, Exp. Neurol., 89 (1985) 484-490.
9. Paganini-Hill, A. and Henderson, V.W., Estrogen deficiency and risk of Alzheimer's disease in women, Am. J. Epidemiol., 140 (1994) 256-261.
10. Paxinos, G. and Watson, C. The Rat Brain in Stereotaxic Atlas, 2 ed., Academic Press, London, 1986.
11. Rainbow, T.C., Parsons, B., MacLusky, N.J. and McEwen, B.S., Estradiol receptor levels in rat hypothalamic and limbic nuclei, J. Neurosci., 2 (1982) 1439-1445.
12. Simerly, R.B., Chang, C., Muramatsu, M. and Swanson, L.W., Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study, J. Comp. Neurol., 294 (1990) 76-95.
13. Singh, M., Meyer, E.M., Millard, W.J. and Simpkins, J.W., Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats, Brain Res., 644 (1994) 305-312.
14. Toran-Allerand, D., Miranda, R.C., Bentham, W.D.L., Sohrabji, F., Brown, T.J., Hochberg, R.B. and MacLusky, N.J., Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain, Proc. Natl. Acad. Sci. USA, 89 (1992) 4668-4672.