Pulsatile perfusion system for ex vivo investigation of biochemical pathways in intact vascular tissue

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 270, Issue 2 39-2, 1996, Pages

  Labadie, Robert F ^a   Antaki, James F ^a   Williams, Jeffrey L ^a   Katyal, Sanjeev ^a   Ligush, John ^a   Watkins, Simon C ^a   Pham, Si M ^a   Borovetz, Harvey S ^a,b  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

control theory; electron microscopy; hemodynamics; vasomotor response

Indexed keywords

ARTERIAL PRESSURE; ARTICLE; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR RESPONSE; CELL METABOLISM; HEMODYNAMICS; HOMEOSTASIS; NONHUMAN; PERFUSION; PRIORITY JOURNAL; PULSATILE FLOW; VASCULAR TISSUE; VASOMOTOR REFLEX;

EID: 0029936856     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.270.2.h760     Document Type: Article

References (29)

1. Berceli, S. A., H. S. Borovetz, R. A. Sheppeck, H. H. Moosa, V. S. Warty, M. A. Armany, and I. H. Herman. Mechanisms of vein graft atherosclerosis: LDL metabolism and endothelial actin reorganization. J. Vase. Surg. 13: 336-347, 1991.
2. Brant, A. M., J. F. Chmielewski, T.-K. Hung, and H. S. Borovetz. Simulation in vitro of pulsatile vascular hemodynamics using a CAD/CAM designed disc cam and roller follower. Artif. Organs 10: 419-421. 1986.
3. Brant, A. M., V. G. J. Rodgers, and H. S. Borovetz. Measurement in vitro of pulsatile arterial diameter using a helium-neon laser. J. Appl. Physiol. 62: 679-683, 1987.
4. Buikema, H., J. G. Grandjean, S. Van Den Broek, W. H. Van Gilst, K. I. Lie, and H. Wesseling. Differences in vasomotor control between human gastroepiploid and left internal mammary artery. Circulation 86, Suppl II: II205-II209, 1992.
5. Close, C. M. The Analysis of Linear Circuits. New York: Harcourt, Brace, and World, 1966, p. 647-652.
6. Furchgott, R. F., and J. V. Zawadzki. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle cells by acetylcholine. Nature Lond. 288: 373-376, 1980.
7. Haudenschild, C. C., K. E. Gould, B. S. Quist, and F. W. Logerfo. Protection of endothelium in vessel segments excised for grafting. Circulation 64, Suppl. II: II101-II107, 1981.
8. Hayashi, T., J. M. Rukuto, L. J. Ignarro, and G. Chaudhure. Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis. Proc. Natl. Acad. Sci. USA 89: 11259-11263, 1992.
9. Herman, I. M., A. M. Brant, V. S. Warty, J. Bonaccorso, E. C. Klein, R. L. Kormos, and H. S. Borovetz. Hemodynamics and the vascular endothelial cytoskeleton. J. Cell Biol. 105: 291-302, 1987.
10. Humphrey, J. D., T. Kang, P. Sakarda, and M. Anjanappa. Computer-aided vascular experimentation: a new electromechanical test system. Ann. Biomed. Eng. 21: 33-43, 1993.
11. Ignarro, L. J., G. M. Buga, and G. Chaudhuri. EDRF generation and release from perfused bovine pulmonary artery and vein. Eur. J. Pharmacol. 149: 79-88, 1986.
12. Ignarro, L. J., R. E. Byrns, and K. D. Wook. Endotheliumdependent modulation of cGMP levels and intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein. Circ. Res. 60: 82-92, 1987.
13. Ives, C. L,. S. G. Eskin, and L. V. McIntire. Mechanical effects on endothelial cell morphology: in-vitro assessment. In Vitro Cell Dev. Biol. 22: 500-507, 1986.
14. Jackson, L. B. Signals, Systems, and Transforms. Reading, MA: Addison-Wesley, 1991, p. 67.
15. Koslow, A. R., R, R. Stromberg, L. I. Friedman, R. J. Lutz, S. L. Hubert, and P. Schuster. A flow system for the study of shear forces upon cultured endothelial cells. J. Biomech. Eng. 108: 338-341, 1986.
16. Labadie, R. F., S. Follonier, H. S. Borovetz, J. Ligush, and J. F. Autaki. An in vitro hemodynamic replication system to be used for exposing vascular tissue to precisely controlled hemodynamics (Abstract). Adv. Bioeng. 22: 497-500, 1992.
17. Ligush, J., R. F. Labadie, S. A. Berceli, J. B. Ochoa, and H. S. Borovetz. Evaluation of endothelium-derived nitric oxide mediated vasodilation utilizing ex-vivo perfusion of an intact vessel. J. Surg Res. 52: 416-421, 1992.
18. McIntire, L. V., J. A, Frangos, S. G Eskin, and E. R. Hall. Effect of hemodynamic shear on arachidonic acid metabolism of vascular endothelium. In: Cerebral Ischemia and Hemorheology, edited by A. Hartmann and W. Kuschinsky. New York: Springer-Verlag, 1987, p. 280-289.
19. Milnor, W. R. Hemodynamics (2nd ed.). Baltimore, MD- Williams and Wilkins, 1989, p. 183.
20. Nichols, W. W., and M. F. O'Rourke. McDonald's Blood Flow in Arteries: Theoretical, Experimental, and Clinical Principles (3rd ed. ). Philadelphia, PA: Lea and Febiger, 1990, p. 216-250.
21. O'Rourke, M. F., R. Kelly, and A. Avolio. The Arterial Pulse. Philadelphia, PA: Lea and Febiger, 1992, p. 45-120, 183, 187.
22. Pohl, U., R. Busse, E. Kuon, and E. Bassenge. Pulsatile perfusion stimulates the release of endothelial autocoids. J. Appl. Cardiol. 1: 215-235, 1986.
23. Rubanyi, G. M., J. C. Romero, and P. M. Vanhoutte. Flowinduced release of endothelium-derived relaxing factor Am. J. Physiol. 250 (Heart Circ. Physiol. 19): H1145-H1149, 1986.
24. Savitsky, A., and M. J. Golay. Smoothing and differentiation of data by simplified least squares procedures. Anal. Chem. 36: 1627-1638, 1964
25. Schima, H., S. Tsangaris, P. Zilla, M. Kadletz, and E. Wolner. Mechanical simulation of shear stress on the walls of peripheral arteries. J. Biomech. 23: 845-851, 1990.
26. Sugawara, M., F. Kajiya, A. Kitabatke, and H. Matsuo. Blood Flow in the Heart and Large Vessels. New York: Springer-Verlag, 1989, p. 74, 79-80.
27. Sumpio, B. E., and A. J. Banes. Prostacyclin synthetic activity in cultured aortic endothelial cells undergoing cyclic mechanical deformation. Surgery 104: 383-389, 1988.
28. Viggers, R. F., A. R. Wechezak, and L. R. Sauvage. An apparatus to study the response of cultured endothelium to shear stress. J. Biomech. Eng. 108: 332-337, 1986.
29. Weizsacker, H. W., H. Lambert, and K. Pascale. Analysis of the passive mechanical properties of rat carotid arteries. J. Biomech. 16: 703-715, 1983.