Cocaine alters cerebral metabolism within the ventral striatum and limbic cortex of monkeys

Journal of Neuroscience

Volumn 16, Issue 3, 1996, Pages 1230-1236

  Lyons, David ^a   Friedman, David P ^a   Nader, Michael A ^a   Porrino, Linda J ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebral metabolism; Cocaine; Limbic system; Monkey; Nucleus accumbens; Orbital and medial prefrontal cortex; Ventral striatum

Indexed keywords

COCAINE; DEOXYGLUCOSE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN METABOLISM; CORPUS STRIATUM; DRUG EFFECT; ELECTROENCEPHALOGRAM; GLUCOSE UTILIZATION; LIMBIC CORTEX; MALE; NONHUMAN; NUCLEUS ACCUMBENS; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRIORITY JOURNAL;

ANIMALS; BRAIN; COCAINE; CORPUS STRIATUM; DENSITOMETRY; DEOXYGLUCOSE; ENERGY METABOLISM; GLUCOSE; IMAGE PROCESSING, COMPUTER-ASSISTED; LIMBIC SYSTEM; MACACA FASCICULARIS; MALE; NEURAL PATHWAYS; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0029936844     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-03-01230.1996     Document Type: Article

References (65)

1. Aggleton JP (1992) The functional effects of amygdala lesions in humans: a comparison with findings from monkeys. In: The amygdala: neurobiological aspects of emotion, memory and mental dysfunction (Aggleton JP, ed), pp 485-504. New York: Wiley.
2. Amaral DG, Price JL, Pitkanen A, Carmichael ST (1992) Anatomical organization of the primate amygdaloid complex. In: The amygdala: neurobiological aspects of emotion, memory and mental dysfunction (Aggleton JP, ed), pp 1-66. New York: Wiley.
3. Apicella P, Ljungberg T, Scarnati E, Schultz W (1991) Responses to reward in monkey dorsal and ventral striatum. Exp Brain Res 85:491-500
4. Baylis LL, Gaffan D (1991) Amygdalectomy and ventromedial prefrontal ablation produce similar deficits in food choice and in simple object discrimination learning for an unseen reward. Exp Brain Res 86:617-622.
5. Berendse HW, Galis-de Graaf Y, Groenewegen HJ (1992) Topographical organization and relationship with ventral striatal compartments of prefrontal corticostriatal projections in the rat. J Comp Neurol 316:314-347.
6. Biegon A, Dillon K, Volkow ND, Fowler JS (1995) Quantitative autoradiographic localization and the characterization of cocaine binding sites in the human brain post-mortem. In: Sites of drug action in the human brain (Biegon A, Volkow ND, eds), pp 87-98. Ann Arbor: CRC.
7. Biegon A, Dillon KA, Volkow ND, Hitzemann RH, Fowler JS, Wolf AP (1992) Quantitative autoradiography of cocaine binding sites in human brain postmortem. Synapse 10:126-130.
8. Colpaert FC, Niemegeers JE, Janssen PAJ (1978) Neuroleptic interference with cocaine cue: internal stimulus control of behavior and psychosis. Psychopharmacology 58:347-367.
9. DeWit H, Wise RA (1977) Blockade of cocaine reinforcement in rats with the dopamine blocker, pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine. Can J Psychol 31:195-203.
10. Fowler JS, Volkow ND, Wolf AP (1995) PET studies of cocaine in human brain. In: Sites of drug action in the human brain (Biegon A, Volkow ND, eds), pp 99-116. Ann Arbor: CRC.
11. Fowler JS, Volkow ND, Wolf AP, Dewey SL, Schlyer DJ, Macgregor RR, Hitzemann R, Logan J, Bendriem B, Galley SJ, Christman D (1989) Mapping cocaine binding sites in human and baboon brain in vivo. Synapse 4:371-377.
12. Friedman DP, Porrino LJ, Vinsant S (1992) Anatomical analysis of the ventral striatum in the macaque monkey. Soc Neurosci Abstr 18:307.
13. Gaffan D (1992) Amygdala and the memory of reward. In: The amygdala: neurobiological aspects of emotion, memory and mental dysfunction (Aggleton JP, ed), pp 485-504. New York: Wiley.
14. Haber SN, Kunishio K, Mizobuchi M, Lynd-Balta E (1995) The orbital and medial prefrontal circuit through the primate basal ganglia. J Neurosci 15:4851-4867.
15. Haber SN, Lynd E, Kleig C, Groenewegen HJ (1990) Topographic organization of the ventral striatal efferent projections in the rhesus monkey: an anterograde tracing study. J Comp Neurol 293:282-298.
16. Kadekaro M, Crane AM, Sokoloff L (1985) Differential effects of electrical stimulation of sciatic nerve on metabolic activity in spinal cord and dorsal root ganglion in the rat. Proc Natl Acad Sci USA 82:6010-6013.
17. Kahn DA, Prohovnik I, Luca LR, Sackeim HA (1989) Dissociated effects of amphetamine on arousal and cortical blood flow in humans. Biol Psychiatry 25:755-767.
18. Kalivas PW, Sorg BA, Hooks MS (1993) The pharmacology and neural circuitry of sensitization to psychostimulants. Behav Pharmacol 4:315-334.
19. 3H]CFT. Synapse 9:177-187.
20. Kennedy C, Sakurada O, Shinohara M, Jehle M, Sokoloff L (1978) Local cerebral glucose utilization in the normal conscious Macaque monkey. J Neurochem 4:293-301.
21. Koe BK (1976) Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain. J Pharmacol Exp Ther 199:649-661.
22. Koob GF, Bloom FE (1988) Cellular and molecular mechanisms of drug dependence. Science 242:715-723.
23. Koob GF, Goeders NE (1989) Neuroanatomical substrates of drug self-administration. In: The neuropharmacological basis of reward (Liebman JM, Cooper ST, eds), pp 214-263. Oxford: Clarendon.
24. Kuhar MJ, Ritz MC, Boja JW (1991) The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci 14:299-302.
25. London ED, Cascella NG, Wong DF, Phillips RL, Dannals RF, Links JM, Herning R, Grayson R, Jaffe JH, Wagner HN (1990) Cocaine-induced reduction of glucose utilization in human brain. Arch Gen Psychiatry 47:567-574.
26. London ED, Wilkerson G, Goldberg SR, Risner ME (1986) Effects of L-cocaine on local cerebral glucose utilization in the rat. Neurosci Lett 68:73-78.
27. Lynd-Balta E, Haber SN (1994a) The organization of midbrain projections to the ventral striatum in the primate. Neuroscience 59:609-623.
28. Lynd-Balta E, Haber SN (1994b) Primate striatonigral projections: a comparison of the sensorimotor-related striatum and the ventral striatum. J Comp Neurol 345:562-578.
29. Madras BK, Kaufman MJ (1994) Cocaine accumulates in dopamine-rich regions of primate brain after i.v. administration: comparison with mazindol distribution. Synapse 18:261-275.
30. Mathew RJ, Wilson WH (1985) Dextroamphetamine-induced changes in regional cerebral blood flow. Psychopharmacology 87:298-302.
31. Meredith GE, Pattiselanno A, Groenewegen HJ, Haber SN (1993) Shell and core in the primate ventral striatum identified with antibodies against calbindin. Soc Neurosci Abstr 19:1435.
32. Miczek KA, Yoshimura H (1982) Disruption of primate social behavior by d-amphetamine and cocaine: differential antagonism by antipsychotics. Psychopharmacology 76:163-171.
33. Mora F, Myers RD (1977) Brain self-stimulation: direct evidence for the involvement of dopamine in the prefrontal cortex. Science 197:1387-1389.
34. Mora F, Avrith DB, Rolls ET (1980) An electrophysiological and behavioural study of self-stimulation in the orbitofrontal cortex of the rhesus monkey. Brain Res Bull 5:111-115.
35. Nader MA, Reboussin DM (1994) The effects of behavioral history on cocaine self-administration in rhesus monkeys. Psychopharmacology 115:53-58.
36. Nestler EJ, Hope BT, Widnell KL (1993) Drug addiction: a model for the molecular basis of neural plasticity. Neuron 11:995-1006.
37. Nishijo H, Ono T, Nishino H (1988) Single neuron responses in amygdala of alert monkey during complex sensory stimulation with affective significance. J Neurosci 8:3570-3583.
38. Pearlson GD, Jeffery PJ, Harris GJ, Ross CA, Fischman MW, Camargo EE (1993) Correlation of acute cocaine-induced changes in local cerebral blood flow with subjective effects. Am J Psychiatry 150:495-497.
39. Phillips AG, Mora F, Rolls ET (1979) Intracranial self-stimulation in orbitofrontal cortex and caudate nucleus of rhesus monkey: effects of apomorphine, pimozide, and spiroperidul. Psychopharmacology 62:79-82.
40. Pontieri FA, Colangelo V, La Riccia M, Pozzilli C, Passarelli F, Orzi F (1994) Psychostimulant drugs increase glucose utilization in the shell of the rat nucleus accumbens. NeuroReport 5:2561-2564.
41. Porrino LJ (1993) Functional effects of cocaine depend on route of administration. Psychopharmacology 112:343-351.
42. Porrino LJ, Lucignani G (1987) Different patterns of local brain energy metabolism associated with high and low doses of methylphenidate: relevance to its action in hyperactive children. Biol Psychiatry 22:126-138.
43. Porrino LJ, Davies HML, Childers SR (1995) Behavioral and local cerebral metabolic effects of the novel tropane analog, 2β-propanoyl-3β-(4-tolyl)-tropane. J Pharmacol Exp Ther 272:901-910.
44. Porrino LJ, Domer FR, Crane AM, Sokoloff L (1988) Selective alterations in cerebral metabolism within the mesocorticolimbic dopaminergic system produced by acute cocaine administration in rats. Neuropsychopharmacology 1:109-118.
45. Pulvirenti L, Berrier R, Kreifeldt M, Koob GF (1994) Modulation of locomotor activity by NMDA receptors in the nucleus accumbens core and shell regions of the rat. Brain Res 664:231-236.
46. Ray JP, Price JL (1993) The organization of projections from the mediodorsal nucleus of the thalamus to orbital and medial prefrontal cortex in macaque monkeys. J Comp Neurol 337:1-31.
47. Ritz MC, Cone EJ, Kuhar MJ (1990) Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study. Life Sci 46:635-645.
48. Ritz MC, Lamb RJ, Goldberg SR, Kuhar MJ (1987) Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 237:1219-1223.
49. Robbins TW, Cador M, Taylor JR, Everitt BJ (1989) Limbic-striatal interactions in reward-related processes. Neurosci Biobehav Rev 13:155-162.
50. Rolls ET, Baylis LL (1994) Gustatory, olfactory, and visual convergence within the primate orbitofrontal cortex. J Neurosci 14:5437-5452.
51. Rolls ET, Burton MJ, Mora F (1980) Neurophysiological analysis of brain-stimulation reward in the monkey. Brain Res 194:339-357.
52. Russchen FT, Bakst I, Amaral DG, Price JL (1985) The amygdaloid projections in the monkey: an anterograde tracing study. Brain Res 329:241-257.
53. Schultz W, Apicella P, Scarnati E, Ljungberg T (1992) Neuronal activity in monkey ventral striatum related to the expectation of reward. J Neurosci 12:4595-4610.
54. Schwartz WJ, Smith CB, Davidsen L, Savaki HE, Sokoloff L, Mata M, Fink DJ, Gainer H (1979) Metabolic mapping of functional activity in the hypothalamo-neurohypophysial system of the rat. Science 205:723-725.
55. Sharkey J, McBean DE, Kelly PAT (1991) Acute cocaine administration: effects on local cerebral blood flow and metabolic demand in the rat. Brain Res 548:310-314.
56. Sokoloff L (1985) Biochemical probes for the localization of functional activities in the central nervous system. In: Perspectives on neuroscience: from molecule to mind (Tsukada Y, ed). pp 327-364. Tokyo: Tokyo UP.
57. 14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure and normal values in the conscious and anesthetized albino rat. J Neurochem 28:897-916.
58. Szabo J, Cowan WM (1984) A stereotaxic atlas of the brain of the cynomolgus monkey (Macaco fascicularis). J Comp Neurol 222:265-300.
59. 2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse 14:169-177.
60. Volkow ND, Fowler JS, Wolf AP, Hitzemann R, Dewey SL, Bendriem B, Alpert R, Hoff A (1991) Changes in brain glucose metabolism in cocaine dependence and withdrawal. Am J Psychiatry 148:621-626.
61. Volkow ND, Hitzemann R, Wang G-J, Fowler JS, Wolf AP, Dewey SL, Handlesman L (1992) Long-term frontal brain metabolic changes in cocaine abusers. Synapse 11:184-190.
62. Weiskrantz L (1956) Behavioural changes associated with ablation of the amygdaloid complex in monkeys. J Comp Physiol Psychol 49:381-391.
63. Wise RA (1978) Catecholamine theories of reward: a critical review. Brain Res 152:215-247.
64. Wolkin A, Angrist B, Wolf A, Brodie J, Wolkin B, Jaeger J, Cancro R, Rotrosen J (1987) Effects of amphetamine on local cerebral metabolism in normal and schizophrenic subjects as determined by positron emission tomography. Psychopharmacology 92:241-246.
65. Zahm DS, Brog JS (1992) On the significance of subterritories in the "accumbens" part of the rat ventral striatum. Neuroscience 50:751-767.