Comparison of the effects of sertraline and its metabolite desmethylsertraline on blockade of central 5-HT reuptake in vivo

Neuropsychopharmacology

Volumn 14, Issue 4, 1996, Pages 225-231

  Sprouse, Jeffrey ^a   Clarke, Thomas ^a   Reynolds, Linda ^a   Heym, James ^a   Rollema, Hans ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Desmethylsertraline; Dorsal raphe nucleus; Electrophysiology; Microdialysis; Selective serotonin reuptake inhibitor; Sertraline; Striatum

Indexed keywords

DRUG METABOLITE; NORSERTRALINE; SEROTONIN; SEROTONIN RECEPTOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

ANIMAL EXPERIMENT; ARTICLE; CORPUS STRIATUM; DEMETHYLATION; DORSAL RAPHE NUCLEUS; DRUG METABOLISM; DRUG STRUCTURE; ELECTROPHYSIOLOGY; IN VIVO STUDY; INTRAVENOUS DRUG ADMINISTRATION; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0029936825     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0893-133X(95)00112-Q     Document Type: Article

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