Should minocycline be used to treat rheumatoid arthritis?

Bulletin on the Rheumatic Diseases

Volumn 45, Issue 2, 1996, Pages 2-5

  Panush, Richard S ^a   Thoburn, Robert ^b  

^a SAINT BARNABAS MEDICAL CENTER   (United States)

^b N Florida Regional Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MINOCYCLINE; TETRACYCLINE DERIVATIVE;

CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HUMAN; META ANALYSIS; REVIEW; RHEUMATOID ARTHRITIS;

ANTI-BACTERIAL AGENTS; ARTHRITIS, RHEUMATOID; CLINICAL TRIALS; FOLLOW-UP STUDIES; HUMANS; MINOCYCLINE; PROGNOSIS;

EID: 0029936737     PISSN: 00075248     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (34)

1. Brown TM, Clark HW, Bailey JS, Gray CW: A mechanistic approach to treatment of rheumatoid type arthritis naturally occurring in a gorilla. Trans Am Clin Climatol Assoc 81:227-247, 1970.
2. Panush RS: What we don't know about rheumatoid arthritis and its therapy. Mediguide Inflam Dis. 9:1-3, 1990.
3. Arthritis Foundation statement concerning theory and treatment of Thomas McPherson Brown M.D. Arthritis Foundation, Atlanta, GA, June 16, 1981.
4. Panush RS: Is there a role for diet or other questionable therapies in managing rheumatic diseases? Bull Rheum Dis 42(4):1-4, 1993.
5. Hess EV, Kramer CC, Linnemann E, Herzig E, Adams LE, Ralz G: Arthritis in gorillas [Abstract]. Arthritis Rheum 26:S56, 1993.
6. Brown TM, Hochberg MC, Hicks JT, Clark HW: Antibiotic therapy of rheumatoid arthritis: a retrospective cohort study of 98 patients with 451 patient years of follow-up [Abstract]. Proceedings of the XVI International Congress of Rheumatology, Sydney, Australia, May 19-25, 1985.
7. Skinner M, Cathcart ES, Mills JA, Pinals RS: Tetracycline in the treatment of rheumatoid arthritis. A double blind controlled study. Arthritis Rheum 17:727-732, 1971.
8. Vaughan JH: Infection and rheumatic diseases: a review. Bull Rheum Dis 39(I):1-7, 39(2):1-8, 1990.
9. Vaughan JH: Infection and rheumatic diseases: a review. Bull Rheum Dis 39(I):1-7, 39(2):1-8, 1990.
10. Crow MK, Friedman SM: Microbial superantigens and autoimmune disease. Bull Rheum Dis 41(3):1-4, 1992.
11. Ad-Hoc Review Committee: Contracts - National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health, Chevy Chase, MD, March 7-8, 1991. RFP No. NIH-NIAMS-90-1 "Clinical centers for an assessment of the efficacy of minocycline in the treatment of rhematoid arthritis."
12. Alarcon GS, Mikhail IS: Antimicrobials in the treatment of rheumatoid arthritis and other arthritides: a clinical perspective. Am J Med Sci 308:201-209, 1994.
13. Greenwald RA: Tetracyclines may be therapeutically beneficial in rhematoid arthritis, but not for the reasons that you think. J Clin Rheumatol 1:185-189, 1995.
14. Alarcon GS: Tetracyclines in the treatment of rheumatoid arthritis: they work but we do not know the reason(s). J Clin Rheumatol 1:190-193, 1995.
15. Kloppenburg M, Breedveld FC, Miltenburg AM, Dijkman BA: Antibiotics as disease modifiers in arthritis. Clin Exp Rehumatol 11(suppl 8):S113-S115, 1993.
16. Pruzanski W, Greenwald RA, Street IP, Laliberte F, Stefanski E, Vadas P: Inhibition of enzymatic activity of phospholipases A2 by minocycline and doxycycline. Biochem Pharmacol 44:1165-1170, 1992.
17. Golub LM, Snomalainen K, Sorsa T: Host modulation with tetracyclines and their chemically modified analogues. Curr Opin Dent 2:80-90, 1992.
18. Nip LH, Uitto VJ, Golub LM: inhibition of epithelial cell matrix inetalloproteinases by tetracyclines. J Periodontal Res 28:379-385, 1993.
19. Breedveld FC, Dijkinans BAC, Mattie H: Minocycline treatment for rheumatoid arthritis: an open dose finding study. J Rheumatol 17:43-46, 1990.
20. Langevitz, P, Bank I, Zemer D, Book M, Pras M: Treatment of resistant rheumatoid arthritis with minocycline: an open study. J Rhematol 19:1502-1504, 1992.
21. Kloppenburg M, Breedveld FC, Terwiel J Ph, Maller C, Dijkmans BAC: Minocycline in active rheumatoid arthritis. A double-blind controlled trial. Arthritis Rheum 37:629-636, 1994.
22. Tilley BC, Alarcon GS, Heyse SP, et al: For the MIRA trial group: minocycline in rheumatoid arthritis. A 48 week, double-blind, placebo-controlled trial. Ann Intern Med 122:81-89, 1995.
23. Sanchez I: Tetracycline treatment in rheumatoid arthritis and other rheumatic diseases. Brazalian J Med 82:21-31, 1968.
24. Kloppenburg M, Mattie H, Douwes N, Dijkmans BA, Breedveld FC: Minocycline in the treatment of rheumatoid arthritis: relationship of serum concentrations to efficacy. J Rheumatol 22:611-616, 1995.
25. Orme M: Plasma concentration and therapeutic effect of anti-inflammatory and anti rheumatic drugs. In Orme M (ed): Antirheumatic Drugs, 1st ed. New York: Pergamon, 1990, pp 217-330.
26. Panush RS, Thoburn R, Breedveld FC, Alarcon GS: Minocycline for rheumatoid arthritis. ACR Hotline Nov 16, 1993.
27. Katz P, Thoburn R: Minocycline for treatment of rheumatoid arthritis. ACR Hotline January 18, 1995.
28. Williams HJ, Wilkens RF, Samuelson CO, et al: Comparison of low-dose oral pulse methotrexate and placebo in the treatment of rheumatoid arthritis. A controlled trial. Arthritis Rheum 28:721-730, 1985.
29. Sukenic S, Buskila D, Neumann L, Kleiner-Bauingarten A: Mud pack therapy in rheumatoid arthritis. Clin Rheumatol 11:243-247, 1992.
30. Panush RS, Carter RL, Katz P, Kowsari B, Longley S, Finnie S: Diet therapy for rheumatoid arthritis. Arthritis Rheum 26:462-471, 1983.
31. Felson DT, Anderson JJ, Boers M, et al: American College of Rheumatology preliminary definition of improvement in rheumatoid arthritis. Arthritis Rheum 38:727-735, 1995.
32. Paulus HE: Minocycline treatment of rheumatoid arthritis [Editorial]. Ann Intern Med 122:147-148, 1995.
33. Kremer JM, Bigauoette J, Michalek A, et al: Effects of manipulatory dietary fish oil on clinical manifestations of rheumatoid arthritis. Lancet 1:184-187, 1985.
34. Food and Drug Administration, Pilot Drug Evaluation Staff Center for Drug Evaluation and Research, Arthritis Advisory Committee Meeting, January 27, 1994.