-
1
-
-
0025048216
-
Effects of non-opioid antitussives on epileptiform activity and NMDA responses in hippocampal and olfactory cortex slices
-
APLAND JP, BRAITMAN DJ. Effects of non-opioid antitussives on epileptiform activity and NMDA responses in hippocampal and olfactory cortex slices. Brain Res 1990: 529: 277-285.
-
(1990)
Brain Res
, vol.529
, pp. 277-285
-
-
Apland, J.P.1
Braitman, D.J.2
-
2
-
-
0023874194
-
Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-D-aspartate in brain slices
-
WONG BY, COULTER DA, CHOI DW, PRINCE DA. Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-D-aspartate in brain slices. Neurosci Lett 1988: 85: 261-266.
-
(1988)
Neurosci Lett
, vol.85
, pp. 261-266
-
-
Wong, B.Y.1
Coulter, D.A.2
Choi, D.W.3
Prince, D.A.4
-
4
-
-
0027254655
-
Dextromethorphan blocks N-methyl-D- aspartate-induced currents and voltage-operated inward currents in cultured cortical neurons
-
NETZER R, PFLIMLIN P, TRUBE G. Dextromethorphan blocks N-methyl-D- aspartate-induced currents and voltage-operated inward currents in cultured cortical neurons. Eur J Pharmacol 1993: 238: 209-216.
-
(1993)
Eur J Pharmacol
, vol.238
, pp. 209-216
-
-
Netzer, R.1
Pflimlin, P.2
Trube, G.3
-
5
-
-
0024397972
-
Dextromethorphan and neuromodulation: Old drug coughs up new activities
-
TORTELLA FC, PELLICANO M, BOWERY NG. Dextromethorphan and neuromodulation: old drug coughs up new activities. Trends Pharmacol Sci 1989: 10: 501-507.
-
(1989)
Trends Pharmacol Sci
, vol.10
, pp. 501-507
-
-
Tortella, F.C.1
Pellicano, M.2
Bowery, N.G.3
-
6
-
-
0025253528
-
Dextromethorphan for treatment of complex partial seizures
-
FISHER RS, CYSYK BJ, LESSER RP, PONTECORNO MJ, FERKANY JT, SCHWERDT PR. Dextromethorphan for treatment of complex partial seizures. Neurology 1990: 40: 547-549.
-
(1990)
Neurology
, vol.40
, pp. 547-549
-
-
Fisher, R.S.1
Cysyk, B.J.2
Lesser, R.P.3
Pontecorno, M.J.4
Ferkany, J.T.5
Schwerdt, P.R.6
-
8
-
-
0025057581
-
Simultaneous determination of dextromethorphan and three metabolites in plasma and urine using high performance liquid chromatography with application to their disposition in man
-
CHEN ZR, SOMOGYI AA, BOCHNER F. Simultaneous determination of dextromethorphan and three metabolites in plasma and urine using high performance liquid chromatography with application to their disposition in man. Ther Drug Monit 1990: 12: 97-104.
-
(1990)
Ther Drug Monit
, vol.12
, pp. 97-104
-
-
Chen, Z.R.1
Somogyi, A.A.2
Bochner, F.3
-
11
-
-
0018975120
-
Urinary excretion of dextromethorphan and three metabolites in dogs and humans
-
BARNHART JW. Urinary excretion of dextromethorphan and three metabolites in dogs and humans. Toxicol Appl Pharmacol 1980: 55: 43-48.
-
(1980)
Toxicol Appl Pharmacol
, vol.55
, pp. 43-48
-
-
Barnhart, J.W.1
-
12
-
-
0020583467
-
Inter-individual variation in the metabolism of dextromethorphan
-
PFAFF G, BRIEGEL P, LAMPBRECHT I. Inter-individual variation in the metabolism of dextromethorphan. Int J Pharmac 1983: 14: 173-189.
-
(1983)
Int J Pharmac
, vol.14
, pp. 173-189
-
-
Pfaff, G.1
Briegel, P.2
Lampbrecht, I.3
-
13
-
-
0343541259
-
Pharmacokinetics of dextromethorphan and dextrorphan: A single dose comparison of three preparations in human volunteers
-
SILVASTI M, KARTTUNEN P, TUKIAINEN H, KOKKONEN P, HANNINEN U, NYKANEN S. Pharmacokinetics of dextromethorphan and dextrorphan: a single dose comparison of three preparations in human volunteers. Int J Clin Pharmacol Ther Toxicol 1987: 25: 493-497.
-
(1987)
Int J Clin Pharmacol Ther Toxicol
, vol.25
, pp. 493-497
-
-
Silvasti, M.1
Karttunen, P.2
Tukiainen, H.3
Kokkonen, P.4
Hanninen, U.5
Nykanen, S.6
-
14
-
-
0024535619
-
Dextromethorphan: Polymorphic serum pattern of the O-demethylated and didemethylated metabolites in man
-
MORTIMER O, LINDSTROM B, LAURELL H, BERGMAN U, RANE A. Dextromethorphan: polymorphic serum pattern of the O-demethylated and didemethylated metabolites in man. Br J Clin Pharmacol 1989: 27: 223-227.
-
(1989)
Br J Clin Pharmacol
, vol.27
, pp. 223-227
-
-
Mortimer, O.1
Lindstrom, B.2
Laurell, H.3
Bergman, U.4
Rane, A.5
-
15
-
-
0023258883
-
High performance liquid chromatographic assays for bufuralol 1′-hydroxylase, debrisoquine 4-hydroxylase and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver
-
KRONBACH T, MATHYS D, GUT J, CATIN J, MEYER UA. High performance liquid chromatographic assays for bufuralol 1′-hydroxylase, debrisoquine 4-hydroxylase and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver. Analytical Biochem 1987: 162: 24-32.
-
(1987)
Analytical Biochem
, vol.162
, pp. 24-32
-
-
Kronbach, T.1
Mathys, D.2
Gut, J.3
Catin, J.4
Meyer, U.A.5
-
16
-
-
0018900001
-
A family and population study of the genetic polymorphism of debrisoquine oxidation in a white European population
-
EVANS DAP, MAHGOUB A, SLOAN TP, IDLE JR, SMITH RL. A family and population study of the genetic polymorphism of debrisoquine oxidation in a white European population. J Med Genet 1980: 17: 102-105.
-
(1980)
J Med Genet
, vol.17
, pp. 102-105
-
-
Evans, D.A.P.1
Mahgoub, A.2
Sloan, T.P.3
Idle, J.R.4
Smith, R.L.5
-
17
-
-
0023954396
-
Human debrisoquine 4-hydroxylation (P450 IIDI):cDNA and deduced amino acid sequence and assignment of the CYP2D6 locus to chromosome 22
-
GONZALEZ FJ, VILBOIS F, HARDWICK JP, et al. Human debrisoquine 4-hydroxylation (P450 IIDI):cDNA and deduced amino acid sequence and assignment of the CYP2D6 locus to chromosome 22. Genomics 1988: 2: 174-179.
-
(1988)
Genomics
, vol.2
, pp. 174-179
-
-
Gonzalez, F.J.1
Vilbois, F.2
Hardwick, J.P.3
-
18
-
-
0025350004
-
Inhibitory studies of mexiletine and dextromethorphan oxidation in human liver microsomes
-
BROLY F, LIBERSA C, LHERMITTE M, DUPUIS B. Inhibitory studies of mexiletine and dextromethorphan oxidation in human liver microsomes. Biochem Pharmacol 1990: 39: 1045-1053.
-
(1990)
Biochem Pharmacol
, vol.39
, pp. 1045-1053
-
-
Broly, F.1
Libersa, C.2
Lhermitte, M.3
Dupuis, B.4
-
19
-
-
0002745061
-
Carbamazepine-biotransformation
-
LEVY R, MATTSON R, MELDRUM B, PENRY JK, DREIFUSS FE, eds. New York: Raven Press
-
FAIGLE JW, FELDMANN KF. Carbamazepine-biotransformation. In: LEVY R, MATTSON R, MELDRUM B, PENRY JK, DREIFUSS FE, eds. Antiepileptic Drugs. New York: Raven Press, 1989: 491-504.
-
(1989)
Antiepileptic Drugs
, pp. 491-504
-
-
Faigle, J.W.1
Feldmann, K.F.2
-
20
-
-
0027285557
-
Neuroprotection following focal cerebral ischemia with the NMDA antagonist dextromethorphan, has a favourable dose response profile
-
STEINBERG GK, KUNIS D, DELAPAZ R, POLJAK A. Neuroprotection following focal cerebral ischemia with the NMDA antagonist dextromethorphan, has a favourable dose response profile. Neurol Res 1993: 15: 174-180.
-
(1993)
Neurol Res
, vol.15
, pp. 174-180
-
-
Steinberg, G.K.1
Kunis, D.2
Delapaz, R.3
Poljak, A.4
-
21
-
-
0026763431
-
Dextromethorphan: Enhancing its systemic availability by way of low-dose quinidine-mediated inhibition of cytochrome 4502D6
-
ZHANG Y, BRITTO MR, VALDERHANG KL, WEDLUND PJ, SMITH RA. Dextromethorphan: enhancing its systemic availability by way of low-dose quinidine-mediated inhibition of cytochrome 4502D6. Clin Pharmacol Ther 1992: 51: 647-655.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 647-655
-
-
Zhang, Y.1
Britto, M.R.2
Valderhang, K.L.3
Wedlund, P.J.4
Smith, R.A.5
-
22
-
-
0027456438
-
Inhibition by fluoxetine of cytochrome P450 2D6 activity
-
OTTON SV, DAFANG W, JOFFE RT, CHEUNG SW, SELLERS EM. Inhibition by fluoxetine of cytochrome P450 2D6 activity. Clin Pharmacol Ther 1993: 53: 401-409.
-
(1993)
Clin Pharmacol Ther
, vol.53
, pp. 401-409
-
-
Otton, S.V.1
Dafang, W.2
Joffe, R.T.3
Cheung, S.W.4
Sellers, E.M.5
-
23
-
-
0027502462
-
Anticonvulsant effect of fluoxetine on locally evoked limbic motor seizures in rats
-
PRENDIVILLE S, GALE K. Anticonvulsant effect of fluoxetine on locally evoked limbic motor seizures in rats. Epilepsia 1993: 34(2): 381-384.
-
(1993)
Epilepsia
, vol.34
, Issue.2
, pp. 381-384
-
-
Prendiville, S.1
Gale, K.2
-
24
-
-
0024512047
-
Neocortical epileptogenesis in vitro: Studies with N-methyl-D-aspartate, phencyclidine, sigma and dextromethorphan receptor ligands
-
ARAM JA, ZEMAN S, MILLAR J, MARTIN D, LODGE D, TOMCZYK M. Neocortical epileptogenesis in vitro: studies with N-methyl-D-aspartate, phencyclidine, sigma and dextromethorphan receptor ligands. J Pharmacol Exp Ther 1989: 248: 320-328.
-
(1989)
J Pharmacol Exp Ther
, vol.248
, pp. 320-328
-
-
Aram, J.A.1
Zeman, S.2
Millar, J.3
Martin, D.4
Lodge, D.5
Tomczyk, M.6
-
25
-
-
0011385725
-
Clinical dose-escalation safety study of the NMDA antagonist dextromethorphan in neurosurgical patients
-
STEINBERG GK, BELL T. Clinical dose-escalation safety study of the NMDA antagonist dextromethorphan in neurosurgical patients. Stroke 1991: 22: 141.
-
(1991)
Stroke
, vol.22
, pp. 141
-
-
Steinberg, G.K.1
Bell, T.2
-
26
-
-
0026446469
-
Kindled rats are more sensitive than non-kindled rats to the behavioural effects of combined treatment with MK-801 and valproate
-
DZIKI M, HONACK D, LOSHER W. Kindled rats are more sensitive than non-kindled rats to the behavioural effects of combined treatment with MK-801 and valproate. Eur J Pharmacol 1992: 22: 273-278.
-
(1992)
Eur J Pharmacol
, vol.22
, pp. 273-278
-
-
Dziki, M.1
Honack, D.2
Losher, W.3
-
27
-
-
0028040424
-
Dextromethorphan: Cellular effects reducing neuronal hyperexcitability
-
TRUBE G, NETZER R. Dextromethorphan: cellular effects reducing neuronal hyperexcitability. Epilepsia 1994: 35(Suppl 5): S62-S67.
-
(1994)
Epilepsia
, vol.35
, Issue.5 SUPPL.
-
-
Trube, G.1
Netzer, R.2
-
28
-
-
0026066411
-
Protection after transient focal cerebral ischemia by the N-methyl-D-Aspartate antagonist is dependent upon plasma and brain levels
-
STEINBERG GK, KUNIS D, SALEH J, DELAPAZ R. Protection after transient focal cerebral ischemia by the N-methyl-D-Aspartate antagonist is dependent upon plasma and brain levels. J Cereb Blood Flow Metab 1991: 11: 1015-1024.
-
(1991)
J Cereb Blood Flow Metab
, vol.11
, pp. 1015-1024
-
-
Steinberg, G.K.1
Kunis, D.2
Saleh, J.3
Delapaz, R.4
-
29
-
-
0006112576
-
Dextromethorphan dextrorphan disposition in rat plasma and brain
-
WILLS RJ, MARTIN KS. Dextromethorphan dextrorphan disposition in rat plasma and brain. Pharm Res 1988: 5(Suppl): S193.
-
(1988)
Pharm Res
, vol.5
, Issue.SUPPL.
-
-
Wills, R.J.1
Martin, K.S.2
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