The histone-like protein H-NS acts as a transcriptional repressor for expression of the anaerobic and growth phase activator AppY of Escherichia coli

Journal of Bacteriology

Volumn 178, Issue 12, 1996, Pages 3418-3425

  Atlung, Tove ^a   Sund, Susanne ^b   Olesen, Kirsten ^a   Brøndsted, Lone ^b  

^a ROSKILDE UNIVERSITY   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CURVED DNA; HISTONE;

ARTICLE; BACTERIAL GROWTH; BINDING SITE; DNA BINDING; ESCHERICHIA COLI; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE SEQUENCE; GROWTH REGULATION; NONHUMAN; OPERON; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; TRANSCRIPTION REGULATION;

ARCA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; HYA;

EID: 0029936379     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.178.12.3418-3425.1996     Document Type: Article

References (40)

1. Atlung, T., and L. Brøndsted. 1994. Role of the transcriptional activator AppY in regulation of the cyx appA operon of Escherichia coli by anaerobiosis, phosphate starvation and growth phase. J. Bacteriol. 176:5414-5422.
2. Atlung, T., A. Nielsen, and F. G. Hansen. 1989. Isolation, characterization, and nucleotide sequence of appY, a regulatory gene for growth-phase-dependent gene expression in Escherichia coli. J. Bacteriol. 171:1683-1691.
3. Bachmann, B. J. 1990. Linkage map of Escherichia coli K-12, edition 8. Microbiol. Rev. 54:130-197.
4. S-dependent genes in Escherichia coli. J. Bacteriol. 177:3455-3464.
5. Bertin, P., P. Lejeune, C. Laurent-Winther, and A. Danchin. 1990. Mutations in bglY, the structural gene for the DNA-binding protein H1, affect expression of several Escherichia coli genes. Biochimie 72:889-891.
6. Birnboim, H. C., and J. Doly. 1979. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 7:1513-1523.
7. Brøndsted, L. 1996. Unpublished results.
8. Brøndsted, L., and T. Atlung. 1994. Anaerobic regulation of the hydrogenase 1 (hya) operon of Escherichia coli. J. Bacteriol. 176:5423-5428.
9. Brøndsted, L., and T. Atlung. 1996. Effect of growth conditions on expression of the acid phosphatase (cyx-appA) operon and the appY gene, which encodes a transcriptional activator of Escherichia coli. J. Bacteriol. 178:1556-1564.
10. Clark, D. J., and O. Maaløe. 1967. DNA replication and the division cycle in Escherichia coli. J. Mol. Biol. 23:99-112.
11. Crothers, D. M., T. E. Haran, and J. G. Nadeau. 1990. Intrinsically bent DNA. J. Biol. Chem. 265:7093-7096.
12. Dersch, P., S. Kneip, and E. Bremer. 1994. The nucleoid-associated DNA-binding protein H-NS is required for the efficient adaptation of Escherichia coli K-12 to a cold environment. Mol. Gen. Genet. 245:255-259.
13. Dersch, P., K. Schmidt, and E. Bremer. 1993. Synthesis of the Escherichia coli K-12 nucleoid-associated DNA-binding protein H-NS is subjected to growth-phase control and autoregulation. Mol. Microbiol. 8:875-889.
14. Drlica, K. 1992. Control of bacterial DNA supercoiling. Mol. Microbiol. 6:425-433.
15. Falconi, M., M. T. Gualtieri, A. La Teana, M. A. Losso, and C. L. Pon. 1988. Proteins from the prokaryotic nucleoid: primary and quaternary structure of the 15-kD Escherichia coli DNA binding protein H-NS. Mol. Microbiol. 2:323-329.
16. Forsman, K., B. Sondén, M. Göransson, and B. E. Uhlin. 1992. Antirepression function in Escherichia coli for the cAMP-cAMP receptor protein transcriptional activator. Proc. Natl. Acad. Sci. USA 89:9880-9884.
17. Gallegos, M.-T., C. Michán, and J. L. Ramos. 1993. The XylS/AraC family of regulators. Nucleic Acids Res. 21:807-810.
18. Göransson, M., B. Sondén, P. Nilsson, B. Dagberg, K. Forsman, K. Emanuelsson, and B. E. Uhlin. 1990. Transcriptional silencing and thermoregulation of gene expression in Escherichia coli. Nature (London) 344:682-685.
19. Higgins, C. F., C. J. Dorman, D. A. Stirling, L. Waddell, I. R. Booth, G. May, and E. Bremer. 1988. A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli. Cell 52:569-584.
20. Hulton, C. S. J., A. Seirafi, J. C. D. Hinton, J. M. Sidebotham, L. Waddell, G. D. Pavitt, T. Owen-Hughes, A. Spassky, H. Buc, and C. F. Higgins. 1990. Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria. Cell 63:631-642.
21. Iuchi, S., V. Chepuri, H.-A. Fu, R. B. Gennis, and E. C. C. Lin. 1990. Requirement for terminal cytochromes in generation of the aerobic signal for the arc regulatory system in Escherichia coli: study utilizing deletions and lac fusions of cyo and cyd. J. Bacteriol. 172:6020-6025.
22. Jordi, B. J. A. M., B. Dagberg, L. A. M. de Haan, A. M. Hamers, B. A. M. der Zeijst, W. Gaastra, and B. E. Uhlin. 1992. The positive regulator CfaD overcomes the repression mediated by histone-like protein H-NS (H1) in the CFA/I fimbrial operon of Escherichia coli. EMBO J. 11:2627-2632.
23. La Teana, A., A. Brandi, M. Falconi, R. Spurio, C. L. Pon, and C. O. Gualerzi. 1991. Identification of a cold shock transcriptional enhancer of the Escherichia coli gene encoding nucleoid protein H-NS. Proc. Natl. Acad. Sci. USA 88:10907-10911.
24. Lucht, J. M., P. Dersch, B. Kempf, and E. Bremer. 1994. Interactions of the nucleoid-associated DNA binding protein H-NS with the regulatory region of the osmotically controlled proU operon of Escherichia coli. J. Biol. Chem. 269:6578-6586.
25. May, G., P. Dersch, M. Haardt, A. Middendorf, and E. Bremer. 1990. The osmZ (bglY) gene encodes the DNA-binding protein H-NS (Hla), a component of the Escherichia coli K-12 nucleoid. Mol. Gen. Genet. 224:81-90.
26. Mizuno, T. 1987. Random cloning of DNA segments from Escherichia coli chromosome and primary characterization of their structures. Nucleic Acids Res. 15:6827-6841.
27. Neidhardt, F. C., P. L. Bloch, and D. F. Smith. 1974. Culture medium for enterobacteria. J. Bacteriol. 119:736-747.
28. Rasmussen, L. J., P. L. Møller, and T. Atlung. 1991. Carbon metabolism regulates expression of the pfl (pyruvate formate-lyase) gene in Escherichia coli. J. Bacteriol. 173:6390-6397.
29. Spassky, A., S. Rimsky, H. Garreau, and H. Buc. 1984. Hla, an E. coli DNA-binding protein which accumulates in stationary phase, strongly compacts DNA in vitro. Nucleic Acids Res. 12:5321-5340.
30. Studier, F. W., and B. A. Moffat. 1986. Use of the bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J. Mol. Biol. 189:113-120.
31. Tanaka, K.-I., S. Muramatsu, H. Yamada, and T. Mizuno. 1991. Systematic characterization of curved DNA segments randomly cloned from Escherichia coli and their functional significance. Mol. Gen. Genet. 226:367-376.
32. Tippner, D., H. Afflerbach, C. Bradaczek, and R. Wagner. 1994. Evidence for a regulatory function of the histone-like Escherichia coli protein H-NS in ribosomal RNA synthesis. Mol. Microbiol. 11:589-604.
33. Tobe, T., S. Nagai, N. Okada, B. Adler, M. Yoshikawa, and C. Sasakawa. 1991. Temperature-regulated expression of invasion genes in Shigella flexneri is controlled through the transcriptional activation of the virB gene on the large plasmid. Mol. Microbiol. 5:887-893.
34. Tobe, T., M. Yoshikawa, T. Mizuno, and C. Sasakawa. 1993. Transcriptional control of the invasion regulatory gene virB of Shigella flexneri: activation by virF and repression by H-NS. J. Bacteriol. 175:6142-6149.
35. Ueguchi, C., M. Kakeda, and T. Mizuno. 1993. Autoregulatory expression of the Escherichia coli hns gene encoding a nucleoid protein: H-NS functions as a repressor of its own transcription. Mol. Gen. Genet. 236:171-178.
36. Ueguchi, C., and T. Mizuno. 1993. The Escherichia coli nucleoid protein H-NS functions directly as a transcriptional repressor. EMBO J. 12:1039-1046.
37. Ussery, D. W., J. C. D. Hinton, B. J. A. M. Jordi, P. E. Granum, A. Seirafi, R. J. Stephen, A. E. Tupper, G. Berridge, J. M. Sidebotham, and C. F. Higgins. 1994. The chromatin-associated protein H-NS. Biochimie 76:968-980.
38. Yamada, H., T. Yoshida, K.-I. Tanaka, C. Sasakawa, and T. Mizuno. 1991. Molecular analysis of the Escherichia coli hns gene encoding a DNA-binding protein, which preferentially recognizes curved DNA sequences. Mol. Gen. Genet. 230:332-336.
39. S, in Escherichia coli: involvement of the nucleoid protein H-NS. EMBO J. 14:594-602.
40. Zuber, F., D. Kotlarz, S. Rimsky, and H. Buc. 1994. Modulated expression of promoters containing upstream curved DNA sequences by the Escherichia coli nucleoid protein H-NS. Mol. Microbiol. 12:231-240.