The latency-related gene of bovine herpesvirus 1 encodes a product which inhibits cell cycle progression

Journal of Virology

Volumn 70, Issue 6, 1996, Pages 3807-3814

  Schang, Luis M ^a   Hossain, Ashfaque ^a   Jones, Clinton ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; BOVINE HERPES VIRUS; CATTLE; CELL CYCLE; CELL SURVIVAL; GENE EXPRESSION; LATENT PERIOD; NONHUMAN; PRIORITY JOURNAL; VIRUS GENE;

EID: 0029936177     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.6.3807-3814.1996     Document Type: Article

References (62)

1. Berns, K. I. 1990. Parvoviridae and their replication, p. 1743-170. In B. N. Fields and D. M. Knipe (ed.), Virology. Raven Press, New York.
2. Bortner, D. M., and M. P. Rosenberg. 1995. Overexpression of cyclin A in the mammary glands of transgenic mice results in the induction of nuclear abnormalities and increased apoptosis. Cell Growth Differ. 6:1579-1589.
3. Bratanich, A. C., N. Hanson, and C. Jones. 1992. The latency related gene of bovine herpesvirus 1 inhibits the activity of immediate early transcription unit 1. Virology 191:988-991.
4. Cai, W., and P. A. Schaffer. 1991. A cellular function can enhance gene expression and plating efficiency of a mutant defective in the gene for ICPO, a trans-activating protein of herpes simplex virus type 1. J. Virol. 65:4078-4090.
5. Cardoso, M. C., H. Leonhardt, and B. Nadal-Ginard. 1993. Reversal of terminal differentiation and control of DNA replication: cyclin A and Cdk2 specificity localize at subnuclear sites of DNA replication. Cell 74:979-992.
6. Chen, J., P. K. Jackson, M. W. Kirschner, and A. Dutta. 1995. Separate domains of p21 involved in the inhibition of cdk kinase and PCNA. Nature (London) 374:386-388.
7. Clarke, A. R., E. R. Maandag, M. van Roon, N. M. T. van der Lugt, M. van der Valk, M. L. Hooper, A. Berns, and H. te Reile. 1992. Requirement for a functional Rb-1 gene in murine development. Nature (London) 359:328-330.
8. Daksis, J. I., and C. M. Preston. 1992. Herpes simplex virus immediate early gene expression in the absence of transinduction by Vmw65 varies during the cell cycle. Virology 189:195-202.
9. de Bruyn Kops, A., and D. M. Knipe. 1988. Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein. Cell 55:857-868.
10. Dowdy, S. F., P. W. Hinds, K. Louie, S. I. Reed, A. Arnold, and R. A. Weinberg. 1993. Physical interaction of the retinoblastoma protein with human D cyclins. Cell 73:499-511.
11. El-Deiry, W. S., T. Tokino, V. E. Velculescu, D. B. Levy, R. Parsons, J. M. Trent, D. Lin, W. E. Mercer, K. W. Kinzler, and B. Vogelstein. 1993. Waf1, a potential mediator of p53 tumor suppressor. Cell 75:817-825.
12. Ewen, M. E., H. K. Sluss, C. J. Sherr, H. Matsushime, J.-Y. Kato, and D. M. Livingston. 1993. Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell 73:487-497.
13. Farrell, M. J., A. T. Dobson, and L. T. Feldman. 1991. Herpes simplex virus latency-associated transcript is a stable intron. Proc. Natl. Acad. Sci. USA 88:790-794.
14. Freeman, R. S., S. Estus, and E. M. Johnson. 1994. Analysis of cell cycle-related gene expression in post mitotic neurons: selective induction of cyclin D1 during programmed cell death. Neuron 12:343-355.
15. Girard, F., U. Strausfeld, A. Fernandez, and N. Lamb. 1991. Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell 67:1169-1179.
16. Goodrich, D. W., N. P. Wang, Y.-W. Quian, E. R.-H. P. Lee, and W.-H. Lee. 1991. The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle. Cell 67:293-302.
17. Gu, W., J. W. Schneider, G. Condorelli, S. Kaushai, V. Mahdavi, and B. Nadai-Ginard. 1993. Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 72:309-324.
18. Guan, K.-L., C. W. Jenkins, Y. Li, M. A. Nichols, X. Wu, C. L. O'Keefe, A. G. Matera, and Y. Xiong. 1994. Growth suppression by p18, a p16ink4/mts1 and p14ink4B/mts2 related CDK6 inhibitor, correlates with wild type Rb activity. Genes Dev. 8:2939-2952.
19. Hao, Y., T. Crenshaw, T. Moulton, E. Newcom, and B. Tycko. 1993. Tumor suppressor activity of H19 RNA. Nature (London) 365:764-767.
20. Harper, J. W., G. R. Adami, N. Wei, K. Keyomarsi, and S. J. Elledge. 1993. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816.
21. Heichman, K. A., and J. M. Roberts. 1994. Rules to replicate by. Cell 79:557-562.
22. Heilbronn, R., and H. zur Hausen. 1989. A subset of herpes simplex virus replication genes induces DNA amplification within the host cell genome. J. Virol. 63:3683-3692.
23. Hilton, J. M., D. Mounghane, T. Mclean, N. V. Contractor, J. O'Neil. K. Carpenter, and S. Bachenheimer. 1995. Induction of herpes simplex virus of free and heterotrimeric forms of E2F transcription factor. Virology 213:624-638.
24. Hinds, P. W., S. Mittnacht, V. Dulic, A. Arnold, S. I. Reed, and R. A. Weinberg. 1992. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell 70:993-1006.
25. Hoang, A. T., K. J. Cohen, J. F. Barrett, D. A. Bergstrom, and C. V. Dang. 1994. Participation of cyclin A in Myc-induced apoptosis. Proc. Natl. Acad. Sci. USA 91:6875-6879.
26. Hossain, A., T. Holt, L. Schang, and C. Jones. Unpublished data.
27. Hossain, A., L. M. Schang, and C. Jones. 1995. Identification of gene products encoded by the latency-related gene of bovine herpesvirus 1. J. Virol. 69:5345-5352.
28. Jacks, T., A. Fazeli, E. Schmitt, R. T. Bronson, M. Goodell, and R. A. Weinberg. 1992. Effects of an Rb mutation in the mouse. Nature (London) 359:295-300.
29. Jang, K.-L., B. Pulverer, J. R. Woodgett, and D. S. Latchman. 1991. Activation of the cellular transcription factor AP-1 in herpes simplex virus infected cells is dependent on the viral immediate-early protein ICP0. Nucleic Acids Res. 19:4879-4883.
30. Koh, J., G. H. Enders, B. D. Dynlacht, and E. Harlow. 1995. Tumour-derived p16 alleles encoding proteins defective in cell cycle inhibition. Nature (London) 375:506-510.
31. Kulomaa, P., J. Paavonen, and M. Lehtinen. 1992. Herpes simplex virus induces unscheduled DNA synthesis in virus-infected cervical cancer cell lines. Res. Virol. 143:351-359.
32. Kutish, G., T. Mainprize, and D. Rock. 1990. Characterization of the latency-related transcriptionally active region of the bovine herpesvirus I genome. J. Virol. 64:5730-5737.
33. Lee, E. Y.-H. P., C.-Y. Chang, N. Hu, Y.-C. J. Wang, C.-C. Lai, K. Herrup, W.-H. Lee, and A. Bradley. 1992. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature (London) 359: 288-294.
34. Lee, E. Y.-H. P., N. Hu, S.-S. F. Yuan, L. A. Cox, A. Bradley, W.-H. Lee, and K. Herrup. 1994. Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 8:2008-2021.
35. Liptak, L. M., S. L. Uprichard, and D. M. Knipe. 1996. Functional order of assembly of herpes simplex virus DNA replication proteins into prereplicative site structures. J. Virol. 70:1759-1767.
36. Livingstone, L. R., A. White, J. Sprouse, E. Livanos, T. Jacks, and T. Thisty. 1992. Altered cell cycle arrest and gene amplification potential accompany loss of wild type p53. Cell 70:923-935.
37. Lucas, J., D. Parry, L. Aagaard, D. J. Mann, J. Bartkova, M. Strauss, G. Peters, and J. Bartek. 1995. Retinoblastoma-protein-dependent cell-cycle inhibition by the tumor suppressor p16. Nature (London) 375:503-506.
38. Lukonis, C. J., and S. K. Weller. 1996. Characterization of nuclear structures in cells infected with herpes simplex virus type 1 in the absence of viral DNA replication. J. Virol. 70:1751-1758.
39. Luo, Y., J. Hurowitz, and J. Massague. 1995. Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1. Nature (London) 375:159-161.
40. Matsuoka, S., M. C. Edwards, C. Bai, S. Parker, P. Zhang, A. Baldini, J. W. Harpe, and S. J. Elledge. 1995. p57Kip2, a structurally distinct member of the p21cip1 cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev. 9:650-662.
41. ink4 requires functional retinoblastoma protein. Proc. Natl. Acad. Sci. USA 92:6289-6293.
42. Meikrantz, W., S. Geisselbrecht, S. W. Tam, and R. Schlegel. 1994. Activation of cyclin A-dependent protein kinases during apoptosis. Proc. Natl. Acad. Sci. USA 91:3754-3758.
43. Pines, J., and T. Hunter. 1990. Human cyclin A is adenovirus E1A associated protein p60 and behaves differently than cyclin B. Nature (London) 346:760-763.
44. Qian, Y., C. Luckey, L. Horton, M. Esser, and D. J. Templeton. 1992. Biological function of the retinoblastoma protein requires distinct domains for hyperphosphorylation and transcription factor binding. Mol. Cell. Biol. 12:5363-5372.
45. Ransone, L. J., and I. M. Verma. 1990. Nuclear proto-oncogenes Fos and Jun. Annu. Rev. Cell Biol. 6:539-557.
46. Rastinejad, F., and H. M. Blau. 1993. Genetic complementation reveals a novel regulatory role for 3′ untranslated regions in growth and differentiation. Cell 72:903-917.
47. Kipl. Mol. Cell. Biol. 15:4347-4352.
48. Rock, D., J. Lokensgard, T. Lewis, and G. Kutish. 1992. Characterization of dexamethasone-induced reactivation of latent bovine herpesvirus 1. J. Virol. 66:2484-2490.
49. Rock, D. L. 1993. The molecular basis of latent infections by alpha herpesviruses. Sem. Virol. 4:157-165.
50. Rock, D. L. 1994. Latent infection with bovine herpesvirus type 1. Sem. Virol. 5:233-240.
51. Sawtell, N. M., and R. L. Thompson. 1992. Herpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency. J. Virol. 66:2157-2169.
52. Schang, L., and C. Jones. Unpublished data.
53. Shew, J.-H., B. T.-Y. Lin, P.-L. Chen, B. Y. Tseng, T. L. Yang-Feng, and W.-H. Lee. 1990. C-terminal truncation of the retinoblastoma gene product leads to functional inactivation. Proc. Natl. Acad. Sci. USA 87:6-10.
54. Templeton, D. J., S. H. Park, L. Lanier, and R. A. Weinberg. 1991. Non-functional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering. Proc. Natl. Acad. Sci. USA 88:3033-3037.
55. Toyoshima, H., and T. Hunter. 1994. p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity is related to p21. Cell 78:67-74.
56. Valyi-Nagi, T., S. Deshmane, A. Dillner, and N. W. Fraser. 1991. Induction of cellular transcription factors in trigeminal ganglia of mice by corneal scarification, herpes simplex virus type 1 infection, and explantation of trigeminal ganglia. J. Virol. 65:4142-4152.
57. Wakada, A. R., D. A. Pryzwara, K. C. Palmer, J. S. Kulkarni, and T. D. Wakada. 1995. Deoxynucleoside induces neuronal apoptosis independent of neurotrophic factors. J. Biol. Chem. 270:17986-17992.
58. Wang, J. K. J., E. S. Knudson, and P. J. Welch. 1994. The retinoblastoma tumor suppressor protein. Adv. Cancer Res. 64:25-85.
59. Weinberg, R. A. 1995. The retinoblastoma protein and cell cycle control. Cell 81:323-3.10.
60. Wilcock, D., and D. P. Lane. 1991. Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells. Nature (London) 349:429-431.
61. Wyler, R., M. Engels, and M. Schwyzer. 1989. Infectious bovine rhinotracheitis/vulvovaginitis (BHV-1), p. 1-72. In G. Wittman (ed.), Herpesvirus diseases of cattle, horses, and pigs. Developments in veterinary medicine. Kluwer Academic Publishers, Boston.
62. Zhu, L., G. Enders, J. A. Lees, R. L. Beijersbergen, R. Bernards, and E. Harlow. 1995. The pRB-related protein p107 contains two growth suppression domains: independent interactions with E2F and cyclin/cdk complexes. EMBO J. 14:1904-1913.