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Volumn 19, Issue 1-2, 1996, Pages 59-70

Comparison of tacrine-induced cytotoxicity in primary cultures of rat, mouse, monkey, dog, rabbit, and human hepatocytes

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CELL ENZYME; LACTATE DEHYDROGENASE; TACRINE;

EID: 0029936176     PISSN: 01480545     EISSN: None     Source Type: Journal    
DOI: 10.3109/01480549609002196     Document Type: Article
Times cited : (13)

References (16)
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  • 2
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    • Hepatotoxicity of tetrahydroaminoacridine in isolated rat hepatocytes: Effect of glutathione and vitamin E
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    • Dogterom, P.1    Nagelkerke, J.F.2    Mulder, G.J.3
  • 4
    • 15144339825 scopus 로고
    • The biotransformation of tetrahydroaminoacridine (THA) in cultured hepatocytes as the cause for relative cytotoxicity in 3 species
    • T. A. Smolarek, C. V. Higgins and D. E. Amacher, The biotransformation of tetrahydroaminoacridine (THA) in cultured hepatocytes as the cause for relative cytotoxicity in 3 species, The Toxicologist 10, 329 (1990).
    • (1990) The Toxicologist , vol.10 , pp. 329
    • Smolarek, T.A.1    Higgins, C.V.2    Amacher, D.E.3
  • 5
    • 2042525344 scopus 로고
    • The role of metabolism in the cytotoxicity of tetrahydroaminoacridine (THA) in hepatocytes
    • D. K. Monteith and J. C. Theiss, The role of metabolism in the cytotoxicity of tetrahydroaminoacridine (THA) in hepatocytes, The Toxicologist 13, 139 (1993).
    • (1993) The Toxicologist , vol.13 , pp. 139
    • Monteith, D.K.1    Theiss, J.C.2
  • 6
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    • Cytotoxicity of tacrine and velnacrine metabolites in cultured rat, dog and human hepatocytes
    • C. J. Viau, R. D. Curren and K. Wallace, Cytotoxicity of tacrine and velnacrine metabolites in cultured rat, dog and human hepatocytes, Drug Chem. Toxicol. 16, 227 (1993).
    • (1993) Drug Chem. Toxicol. , vol.16 , pp. 227
    • Viau, C.J.1    Curren, R.D.2    Wallace, K.3
  • 7
    • 0027326685 scopus 로고
    • An investigation into the formation of stable, protein-reactive and cytotoxic metabolites from tacrine in vitro
    • S. Madden, T. F. Woolf, W. F. Pool and B. K. Park, An investigation into the formation of stable, protein-reactive and cytotoxic metabolites from tacrine in vitro, Biochem. Pharmacol. 46, 13 (1993).
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 13
    • Madden, S.1    Woolf, T.F.2    Pool, W.F.3    Park, B.K.4
  • 8
    • 0020336393 scopus 로고
    • Primary cultures and the levels of cytochrome P450 in hepatocytes from mouse, rat, hamster, and rabbit liver
    • C. J. Maslansky and G. M. Williams, Primary cultures and the levels of cytochrome P450 in hepatocytes from mouse, rat, hamster, and rabbit liver, In Vitro 18, 683 (1982)
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    • Maslansky, C.J.1    Williams, G.M.2
  • 10
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    • A comparison of the inhibition of deacetylase in primary cultures of rat and human hepatocytes effecting metabolism and binding of 2-acetylaminofluorene
    • D. K. Monteith and S. C. Strom, A comparison of the inhibition of deacetylase in primary cultures of rat and human hepatocytes effecting metabolism and binding of 2-acetylaminofluorene, Cell Biol Toxicol. 6, 269 (1990).
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    • Monteith, D.K.1    Strom, S.C.2
  • 12
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    • High-yield preparation of isolated rat liver parenchymal cells: A biochemical and fine structural analysis
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    • Berry, M.N.1    Friend, D.S.2
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    • Preparation of isolated rat liver cells
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  • 16
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    • W McNally, M. Roth, R. Young, H. Bockbrader and T. Chang, Quantitative whole-body autoradiographic detemination of tacrine tissue distribution in rats following intravenous or oral dose, Pharmaceutical Res. 6, 924 (1989).
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    • McNally, W.1    Roth, M.2    Young, R.3    Bockbrader, H.4    Chang, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.