Covalently closed circular viral DNA formed from two types of linear DNA in woodchuck hepatitis virus-infected liver

Journal of Virology

Volumn 70, Issue 7, 1996, Pages 4567-4575

  Yang, Wengang ^a   Mason, William S ^b   Summers, Jesse ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCULAR DNA; VIRUS DNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; DNA SYNTHESIS; GENE DUPLICATION; GENETIC RECOMBINATION; HEPATITIS VIRUS; NONHUMAN; PRIORITY JOURNAL; VIRUS NUCLEOCAPSID; VIRUS REPLICATION; VIRUS TYPING; WOODCHUCK;

EID: 0029936171     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.7.4567-4575.1996     Document Type: Article

References (33)

1. Bartenschlager, R., M. Junker-Niepmann, and H. Schaller. 1990. The P gene product of hepatitis B virus is required as a structural component for genomic RNA encapsidation. J. Virol. 64:5324-5332.
2. Birnboim, H. C., and J. Doly. 1979. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 7:1513-1523.
3. Condreay, L. D., T. T. Wu, C. E. Aldrich, M. A. Delaney, J. Summers, C. Seeger, and W. S. Mason. 1992. Replication of DHBV genomes with mutations at the sites of initiation of minus- and plus-strand DNA synthesis. Virology 188:208-216.
4. Enders, G. H., D. Ganem, and H. E. Varmus. 1987. 5′-terminal sequences influence the segregation of ground squirrel hepatitis virus RNAs into polyrihosomes and viral core particles. J. Virol. 61:35-41.
5. Feitelson, M. A., L. X. Duan, J. Guo, and B. S. Blumberg. 1995. X region deletion mutants associated with surface antigen-positive hepatitis B virus infections. Gastroenterology 188:1810-1819.
6. Feitelson, M. A., L. X. Duan, J. Guo, B. Sun, J. Woo, K. Steensma, N. Horiike, and B. S. Blumberg. 1995. X region deletion variants of hepatitis B virus in surface antigen-negative infections and non-A, non-B hepatitis. J. Infect. Dis. 172:713-722.
7. Feitelson, M., L. X. Duan, N. Horiike, and M. Clayton. 1991. Hepatitis B X open reading frame deletion mutants isolated from atypical hepatitis B virus infections. Hepatology 13:S58-S60.
8. Feitelson, M., L. Lega, J. Guo, M. Resti, M. E. Rossi, C. Azzari, B. S. Blumberg, and A. Vierucci. 1994. Pathogenesis of posttransfusion viral hepatitis in children with beta-thalessemia. Hepatology 19:558-568.
9. Horwich, A. L., K. Furtak, J. C. Pugh, and J. Summers. 1990. Synthesis of hepadnavirus particles containing replication-defective duck hepatitis B virus genomes in cultured Huh-7 cells. J. Virol. 64:642-650.
10. Junker-Niepmann, M., R. Bartenschlager, and H. Schaller. 1990. A short as-acting sequence is required for hepatitis B virus pregenome encapsidation and sufficient for packaging of foreign RNA. EMBO J. 9:3389-3396.
11. Kajino, K., A. R. Jilbert, J. Saputelli, C. E. Aldrich, J. Cullen, and W. S. Mason. 1994. Woodchuck hepatitis virus infections: very rapid recovery after a prolonged viremia and infection of virtually every hepatocyte. J. Virol. 68:5792-5803.
12. Kew, M. C., R. H. Miller, H. S. Chen, B. C. Tennant, and R. H. Purcell. 1993. Mutant woodchuck hepatitis virus genomes from virions resemble rearranged hepadnaviral integrants in hepatocellular carcinoma. Proc. Natl. Acad. Sci. USA 90:10211-10215.
13. Kodama, K., N. Ogasawara, H. Yoshikawa, and S. Murakami. 1985. Nucleotide sequence of a cloned woodchuck hepatitis virus genome: evolutional relationship between hepadnaviruses. J. Virol. 56:978-986.
14. Lien, J. M., C. Aldrich, and W. S. Mason. 1986. Evidence that a capped oligonucleotide is the primer for duck hepatitis B virus plus-strand DNA synthesis. J. Virol. 57:229-236.
15. Lien, J. M., D. Petcu, C. Aldrich, and W. S. Mason. 1987. Initiation and termination of duck hepatitis B virus DNA synthesis during virus maturation. J. Virol. 61:3832-3840.
16. Loeb, D., R. Hirsch, and D. Ganem. 1991. Sequence-independent RNA cleavages generate the primers for plus strand DNA synthesis in hepatitis B viruses: implications for other reverse transcribing elements. EMBO J. 10: 3533-3540.
17. Mason, W. S., C. Aldrich, J. Summers, and J. M. Taylor. 1982. Asymmetric replication of duck hepatitis B virus DNA in liver cells (free minus strand DNA). Proc. Natl. Acad. Sci. USA 79:3997-4001.
18. Mason, W. S., G. Seal, and J. Summers. 1980. A virus of Pekin ducks with structural and biological relatedness to human hepatitis B virus. J. Virol. 36:829-836.
19. Nassal, M., M. Junker-Niepmann, and H. Schaller. 1990. Translational inactivation of RNA function: discrimination against a subset of genomic transcripts during HBV nucleocapsid assembly. Cell 63:1357-1363.
20. Seeger, C., D. Ganem, and H. E. Varmus. 1986. Biochemical and genetic evidence for the hepatitis B virus replication strategy. Science 232:477-484.
21. Seeger, C., and J. Maragos. 1989. Molecular analysis of the function of direct repeats and a polypurine tract for plus-strand DNA priming in woodchuck hepatitis virus. J. Virol. 63:1907-1915.
22. Seeger, C., and J. Maragos. 1990. Identification and characterization of the woodchuck hepatitis virus origin of DNA replication. J. Virol. 64:16-23.
23. Staprans, S., D. Loeb, and D. Ganem. 1991. Mutations affecting hepadnavirus plus-strand synthesis dissociate primer cleavage from translocation and reveal the origin of linear viral DNA. J. Virol. 65:1255-1262.
24. Summers, J., and W. S. Mason. 1982. Replication of the genome of hepatitis B-like virus by reverse transcription of an RNA intermediate. Cell 29:403-415.
25. Summers, J., A. O'Connell, and I. Millman. 1975. Genome of hepatitis B virus: restriction enzyme cleavage and structure of the DNA extracted from Dane particles. Proc. Natl. Acad. Sci. USA 72:4597-4601.
26. Summers, J., P. Smith, and A. L. Horwich. 1990. Hepadnaviral envelope proteins regulate amplification of covalently closed circular DNA. J. Virol. 64:2819-2824.
27. Summers, J., P. Smith, M. Huang, and M. Vu. 1991. Regulatory and morphogenetic effects of mutations in the envelope proteins of an avian hepadnavirus. J. Virol. 65:1310-1317.
28. Summers, J., J. M. Smolec, and R. Snyder. 1978. A virus similar to hepatitis B virus associated with hepatitis and hepatoma in woodchucks. Proc. Natl. Acad. Sci. USA 75:4533-4537.
29. Tuttleman, J., C. Pourcel, and J. Summers. 1986. Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells. Cell 47:451-460.
30. Wang, G., and C. Seeger. 1993. Novel mechanism for reverse transcription in hepatitis B viruses. J. Virol. 67:6507-6512.
31. Wang, H.-P., and C. E. Rogler. 1991. Topoisomerase I-mediated integration of hepadnaviral DNA in vitro. J. Virol. 65:2381-2392.
32. Wu, T.-T., L. Coates, C. E. Aldrich, J. Summers, and W. S. Mason. 1990. In hepatocytes infected with duck hepatitis B virus, the template for viral RNA synthesis is amplified by an intracellular pathway. Virology 175:255-261.
33. Yang, W., and J. Summers. 1995. Illegitimate replication of linear hepadnaviral DNA through nonhomologous recombination. J. Virol. 69:4029-4036.