Synthesis, physical properties, toxicological studies and bioavailability of L-pyroglutamic and L-glutamic acid esters of paracetamol as potentially useful prodrugs

Journal of Pharmacy and Pharmacology

Volumn 48, Issue 5, 1996, Pages 479-485

  Bousquet, E ^a   Marrazzo, A ^a   Puglisi, G ^a   Spadaro, A ^a   Tirendi, S ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ESTER DERIVATIVE; GLUTAMIC ACID DERIVATIVE; PARACETAMOL; PARACETAMOL DERIVATIVE; PRODRUG; PYROGLUTAMIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG HYDROLYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; LD 50; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHYSICAL CHEMISTRY; RABBIT;

EID: 0029936074     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1996.tb05958.x     Document Type: Article

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