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Volumn 67, Issue 1, 1996, Pages 201-211

Ethanol-induced inhibition of [3H]thienylcyclohexylpiperidine (TCP) binding to NMDA receptors in brain synaptic membranes and to a purified protein complex

Author keywords

Ethanol; NMDA receptor like complex; NMDA receptors; Synaptic membranes; 3H Thienylcyclohexylpiperidine binding

Indexed keywords

ALCOHOL; DIZOCILPINE; GLUTAMIC ACID; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TENOCYCLIDINE;

EID: 0029935875     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.67010201.x     Document Type: Article
Times cited : (11)

References (66)
  • 2
    • 0030296663 scopus 로고    scopus 로고
    • A synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine (TCP)-binding protein: Isolation and immunochemical characterization
    • in press
    • Babcock K. K., Chen X., Eggeman K. T., Kumar K. N., Decedue C. J., and Michaelis E. K. (1996) A synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine (TCP)-binding protein: isolation and immunochemical characterization. Neurochem. Int. (in press).
    • (1996) Neurochem. Int.
    • Babcock, K.K.1    Chen, X.2    Eggeman, K.T.3    Kumar, K.N.4    Decedue, C.J.5    Michaelis, E.K.6
  • 4
    • 0023677623 scopus 로고
    • N-Methyl-D-aspartate receptor regulation of uncompetitive antagonist binding in rat brain membranes: Kinetic analysis
    • Bonhaus D. W. and McNamara J. O. (1988) N-Methyl-D-aspartate receptor regulation of uncompetitive antagonist binding in rat brain membranes: kinetic analysis. Mol. Pharmacol. 34, 250-255.
    • (1988) Mol. Pharmacol. , vol.34 , pp. 250-255
    • Bonhaus, D.W.1    McNamara, J.O.2
  • 5
    • 0027490681 scopus 로고
    • Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDAR1
    • Brose N., Gasic G. P., Vetter D. E., Sullivan J. M., and Heinemann S. F. (1993) Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDAR1. J. Biol. Chem. 268, 22663-22671.
    • (1993) J. Biol. Chem. , vol.268 , pp. 22663-22671
    • Brose, N.1    Gasic, G.P.2    Vetter, D.E.3    Sullivan, J.M.4    Heinemann, S.F.5
  • 6
    • 0020562171 scopus 로고
    • A rapid filtration assay for soluble receptors using polyethylenimine-treated filters
    • Bruns R. F., Lawson-Wendling K., and Pugsley T. A. (1983) A rapid filtration assay for soluble receptors using polyethylenimine-treated filters. Anal. Biochem. 132, 74-81.
    • (1983) Anal. Biochem. , vol.132 , pp. 74-81
    • Bruns, R.F.1    Lawson-Wendling, K.2    Pugsley, T.A.3
  • 7
    • 0027336329 scopus 로고
    • Ethanol prevents the glutamate release induced by N-methyl-D-aspartate in the rat striatum
    • Carboni S., Isola R., Gessa G. L., and Rossetti Z. L. (1993) Ethanol prevents the glutamate release induced by N-methyl-D-aspartate in the rat striatum. Neurosci. Lett. 152, 133-136.
    • (1993) Neurosci. Lett. , vol.152 , pp. 133-136
    • Carboni, S.1    Isola, R.2    Gessa, G.L.3    Rossetti, Z.L.4
  • 8
    • 0027461925 scopus 로고
    • Chronic ethanol exposure potentiates NMDA excitotoxicity in cerebral cortical neurons
    • Chandler L. J., Newsom H., Sumners C., and Crews F. (1993) Chronic ethanol exposure potentiates NMDA excitotoxicity in cerebral cortical neurons. J. Neurochem. 60, 1578-1581.
    • (1993) J. Neurochem. , vol.60 , pp. 1578-1581
    • Chandler, L.J.1    Newsom, H.2    Sumners, C.3    Crews, F.4
  • 9
    • 0023905226 scopus 로고
    • Immune labeling and purification of a 71kDa glutamate binding protein from brain synaptic membranes
    • Chen J.-W., Cunningham M. D., Galton N., and Michaelis E. K. (1988) Immune labeling and purification of a 71kDa glutamate binding protein from brain synaptic membranes. J. Biol. Chem. 263, 417-427.
    • (1988) J. Biol. Chem. , vol.263 , pp. 417-427
    • Chen, J.-W.1    Cunningham, M.D.2    Galton, N.3    Michaelis, E.K.4
  • 10
    • 4243962434 scopus 로고
    • Chronic alcohol intake increases the expression of four neuronal proteins associated with an NMDA/glutamate receptor complex
    • Chen X., Michaelis E. K., and Michaelis M. L. (1995) Chronic alcohol intake increases the expression of four neuronal proteins associated with an NMDA/glutamate receptor complex. Alcohol. Clin. Exp. Res. 19, 7A.
    • (1995) Alcohol. Clin. Exp. Res. , vol.19
    • Chen, X.1    Michaelis, E.K.2    Michaelis, M.L.3
  • 11
    • 0029074490 scopus 로고
    • Ethanol inhibition of recombinant heteromeric NMDA channels in the presence and absence of modulators
    • Chu B., Anantharam V., and Treistman S. N. (1995) Ethanol inhibition of recombinant heteromeric NMDA channels in the presence and absence of modulators. J. Neurochem. 65, 140-148.
    • (1995) J. Neurochem. , vol.65 , pp. 140-148
    • Chu, B.1    Anantharam, V.2    Treistman, S.N.3
  • 12
    • 0025159283 scopus 로고
    • Evidence for a functional coupling of the NMDA and glycine recognition sites in synaptic plasma membranes
    • Compton R. P., Hood W. F., and Monahan J. B. (1990) Evidence for a functional coupling of the NMDA and glycine recognition sites in synaptic plasma membranes. Eur. J. Pharmacol. 188, 63-70.
    • (1990) Eur. J. Pharmacol. , vol.188 , pp. 63-70
    • Compton, R.P.1    Hood, W.F.2    Monahan, J.B.3
  • 13
    • 0025321160 scopus 로고
    • 3H]propyl-1-phosphonic acid recognition proteins from rat brain synaptic membranes
    • 3H]propyl-1-phosphonic acid recognition proteins from rat brain synaptic membranes. J. Biol. Chem. 265, 7768-7778.
    • (1990) J. Biol. Chem. , vol.265 , pp. 7768-7778
    • Cunningham, M.D.1    Michaelis, E.K.2
  • 16
    • 0026686821 scopus 로고
    • Cloning of an apparent splice variant of the rat NMDA receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C
    • Durand G. M., Gregor P., Zheng X., Bennett M. V. L., Uhl G. R., and Zukin R. S. (1992) Cloning of an apparent splice variant of the rat NMDA receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C. Proc. Natl. Acad. Sci. USA 89, 9359-9363.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9359-9363
    • Durand, G.M.1    Gregor, P.2    Zheng, X.3    Bennett, M.V.L.4    Uhl, G.R.5    Zukin, R.S.6
  • 17
    • 0026707947 scopus 로고
    • Alcohol withdrawal reaction as a result of adaptive changes of excitatory amino acid receptors
    • Engberg G. and Hajos M. (1992) Alcohol withdrawal reaction as a result of adaptive changes of excitatory amino acid receptors. Naunyn Schmiedebergs Arch. Pharmacol. 346, 437-441.
    • (1992) Naunyn Schmiedebergs Arch. Pharmacol. , vol.346 , pp. 437-441
    • Engberg, G.1    Hajos, M.2
  • 18
    • 0024426896 scopus 로고
    • Inhibition of NMDA- and L-glutamate-induced noradrenaline and acetylcholine release in the rat brain by ethanol
    • Gothert M. and Fink K. (1989) Inhibition of NMDA- and L-glutamate-induced noradrenaline and acetylcholine release in the rat brain by ethanol. Naunyn Schmiedebergs Arch. Pharmacol. 340, 516-521.
    • (1989) Naunyn Schmiedebergs Arch. Pharmacol. , vol.340 , pp. 516-521
    • Gothert, M.1    Fink, K.2
  • 20
    • 0027232162 scopus 로고
    • Interactions between the glutamate and glycine recognition sites of the N-methyl-D-aspartate receptor from rat brain, as revealed from radioligand binding studies
    • Grimwood S., Wilde G. J. C., and Foster A. C. (1993) Interactions between the glutamate and glycine recognition sites of the N-methyl-D-aspartate receptor from rat brain, as revealed from radioligand binding studies. J. Neurochem. 60, 1729-1738.
    • (1993) J. Neurochem. , vol.60 , pp. 1729-1738
    • Grimwood, S.1    Wilde, G.J.C.2    Foster, A.C.3
  • 21
    • 0025731207 scopus 로고
    • Brain regional specificity and time-course of changes in the NMDA receptor-ionophore complex during ethanol withdrawal
    • Guyla K., Grant K. A., Valverius P., Hoffman P. L., and Tabakoff B. (1991) Brain regional specificity and time-course of changes in the NMDA receptor-ionophore complex during ethanol withdrawal, Brain Res. 547, 129-134.
    • (1991) Brain Res. , vol.547 , pp. 129-134
    • Guyla, K.1    Grant, K.A.2    Valverius, P.3    Hoffman, P.L.4    Tabakoff, B.5
  • 22
    • 0024348985 scopus 로고
    • N-Methyl-D-asparate receptors and ethanol: Inhibition of calcium flux and cyclic GMP production
    • Hoffman P. L., Rabe C. S., Moses F., and Tabakoff B. (1989) N-Methyl-D-asparate receptors and ethanol: inhibition of calcium flux and cyclic GMP production. J. Neurochem. 52, 1937-1940.
    • (1989) J. Neurochem. , vol.52 , pp. 1937-1940
    • Hoffman, P.L.1    Rabe, C.S.2    Moses, F.3    Tabakoff, B.4
  • 23
    • 0027197230 scopus 로고
    • Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor
    • Hollmann M., Boulter J., Maron C., Beasley L., Sullivan J., Pecht G., and Heinemann S. (1993) Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor. Neuron 10, 943-954.
    • (1993) Neuron , vol.10 , pp. 943-954
    • Hollmann, M.1    Boulter, J.2    Maron, C.3    Beasley, L.4    Sullivan, J.5    Pecht, G.6    Heinemann, S.7
  • 24
    • 0025253944 scopus 로고
    • N-Methyl-D-asparate/phencyclidine receptor complex of rat forebrain: Purification and biochemical characterization
    • Ikin A. F., Kloog Y., and Sokolvsky M. (1990) N-Methyl-D-asparate/phencyclidine receptor complex of rat forebrain: purification and biochemical characterization. Biochemistry 29, 2290-2295.
    • (1990) Biochemistry , vol.29 , pp. 2290-2295
    • Ikin, A.F.1    Kloog, Y.2    Sokolvsky, M.3
  • 25
    • 0027076781 scopus 로고
    • Chronic exposure of cerebellar granule cells to ethanol results in increased NMDA receptor function
    • Iorio K. R., Reinlib L., Tabakoff B., and Hoffman P. L. (1992) Chronic exposure of cerebellar granule cells to ethanol results in increased NMDA receptor function. Mol. Pharmacol. 41, 1142-1148.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 1142-1148
    • Iorio, K.R.1    Reinlib, L.2    Tabakoff, B.3    Hoffman, P.L.4
  • 26
    • 0027248420 scopus 로고
    • Glutamate-induced neurotoxicity is increased in cerebellar granule cells exposed chronically to ethanol
    • Iorio K. R., Tabakoff B., and Hoffman P. L. (1993) Glutamate-induced neurotoxicity is increased in cerebellar granule cells exposed chronically to ethanol. Eur. J. Pharmacol. 248, 209-212.
    • (1993) Eur. J. Pharmacol. , vol.248 , pp. 209-212
    • Iorio, K.R.1    Tabakoff, B.2    Hoffman, P.L.3
  • 27
    • 0024477121 scopus 로고
    • 3H]MK-801 binding: Evidence for access to closed and open N-methyl-D-asparate receptor channels
    • 3H]MK-801 binding: evidence for access to closed and open N-methyl-D-asparate receptor channels. Mol. Pharmacol. 35, 387-393.
    • (1989) Mol. Pharmacol. , vol.35 , pp. 387-393
    • Javitt, D.C.1    Zukin, S.R.2
  • 28
    • 0024564076 scopus 로고
    • A glycine site associated with N-methyl-D-aspartic acid receptors: Characterization and identification of a new class of antagonists
    • Kessler M., Terramani T., Lynch G., and Baudry M. (1989) A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists. J. Neurochem. 52, 1319-1328.
    • (1989) J. Neurochem. , vol.52 , pp. 1319-1328
    • Kessler, M.1    Terramani, T.2    Lynch, G.3    Baudry, M.4
  • 29
    • 0026419342 scopus 로고
    • Cloning of cDNA for the glutamate-binding subunit of an NMDA receptor complex
    • Kumar K. N., Tilakaratne N., Johnson P. S., Allen A. E., and Michaelis E. K. (1991) Cloning of cDNA for the glutamate-binding subunit of an NMDA receptor complex. Nature 354, 70-73.
    • (1991) Nature , vol.354 , pp. 70-73
    • Kumar, K.N.1    Tilakaratne, N.2    Johnson, P.S.3    Allen, A.E.4    Michaelis, E.K.5
  • 30
    • 0027945168 scopus 로고
    • Purification and pharmacological and immunochemical characterization of synaptic membrane proteins with ligand-binding properties of N-methyl-D-asparate receptors
    • Kumar K. N., Babcock K. K., Johnson P. S., Chen X., Eggeman K. T., and Michaelis E. K. (1994a) Purification and pharmacological and immunochemical characterization of synaptic membrane proteins with ligand-binding properties of N-methyl-D-asparate receptors. J. Biol. Chem. 269, 27384-27393.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27384-27393
    • Kumar, K.N.1    Babcock, K.K.2    Johnson, P.S.3    Chen, X.4    Eggeman, K.T.5    Michaelis, E.K.6
  • 34
    • 0024601948 scopus 로고
    • Ethanol potentiates and blocks NMDA-activated single channel currents in rat hippocampal pyramidal cells
    • Lima-Landman M. T. and Albuquerque E. X. (1989) Ethanol potentiates and blocks NMDA-activated single channel currents in rat hippocampal pyramidal cells. FEBS Lett. 247, 61-67.
    • (1989) FEBS Lett. , vol.247 , pp. 61-67
    • Lima-Landman, M.T.1    Albuquerque, E.X.2
  • 35
    • 0024535962 scopus 로고
    • Ethanol inhibits NMDA-activated ion currents in hippocampal neurons
    • Lovinger D. M., White G., and Weight F. F. (1989) Ethanol inhibits NMDA-activated ion currents in hippocampal neurons. Science 243, 1721-1724.
    • (1989) Science , vol.243 , pp. 1721-1724
    • Lovinger, D.M.1    White, G.2    Weight, F.F.3
  • 36
    • 0025868929 scopus 로고
    • Solubilization, partial purification, and reconstitution of glutamate- and N-methyl-D-aspartate-activated cation channels from brain synaptic membranes
    • Ly A. M. and Michaelis E. K. (1991) Solubilization, partial purification, and reconstitution of glutamate- and N-methyl-D-aspartate-activated cation channels from brain synaptic membranes. Biochemistry 30, 4307-4316.
    • (1991) Biochemistry , vol.30 , pp. 4307-4316
    • Ly, A.M.1    Michaelis, E.K.2
  • 37
    • 0025008928 scopus 로고
    • An endogenous modulator of N-methyl-D-aspartate receptor-coupled glycine receptors
    • Marvizon J.-C. and Skolnick P. (1990) An endogenous modulator of N-methyl-D-aspartate receptor-coupled glycine receptors. Eur. J. Pharmacol. 188, 23-32.
    • (1990) Eur. J. Pharmacol. , vol.188 , pp. 23-32
    • Marvizon, J.-C.1    Skolnick, P.2
  • 38
    • 0028081936 scopus 로고
    • Differential ethanol sensitivity of recombinant N-methyl-D-aspartate receptor subunits
    • Masood K., Wu C., Brauneis U., and Weight F. F. (1994) Differential ethanol sensitivity of recombinant N-methyl-D-aspartate receptor subunits. Mol. Pharmacol. 45, 324-329.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 324-329
    • Masood, K.1    Wu, C.2    Brauneis, U.3    Weight, F.F.4
  • 39
    • 0025938452 scopus 로고
    • Developmental expression, compartmentalization, and possible role in excitotoxicity of the putative glutamate receptor protein in cultured hippocampal neurons
    • Mattson M. P., Wong H., and Michaelis E. K. (1991) Developmental expression, compartmentalization, and possible role in excitotoxicity of the putative glutamate receptor protein in cultured hippocampal neurons. Brain Res. 565, 94-108.
    • (1991) Brain Res. , vol.565 , pp. 94-108
    • Mattson, M.P.1    Wong, H.2    Michaelis, E.K.3
  • 40
    • 0027332958 scopus 로고
    • Basic FGF regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in hippocampal neurons
    • Mattson M. P., Kumar K. N., Wang H., Cheng B., and Michaelis E. K. (1993) Basic FGF regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in hippocampal neurons. J. Neurosci. 13, 4575-4588.
    • (1993) J. Neurosci. , vol.13 , pp. 4575-4588
    • Mattson, M.P.1    Kumar, K.N.2    Wang, H.3    Cheng, B.4    Michaelis, E.K.5
  • 42
    • 0023256139 scopus 로고
    • Correlation of glutamate binding activity with glutamate-binding protein immunoreactivity in the brain of control and alcohol-treated rats
    • Michaelis E. K., Roy S., Galton N., Cunningham M., LeCluyse E., and Michaelis M. L. (1987) Correlation of glutamate binding activity with glutamate-binding protein immunoreactivity in the brain of control and alcohol-treated rats. Neurochem. Int. 11, 209-218.
    • (1987) Neurochem. Int. , vol.11 , pp. 209-218
    • Michaelis, E.K.1    Roy, S.2    Galton, N.3    Cunningham, M.4    LeCluyse, E.5    Michaelis, M.L.6
  • 47
    • 0019061918 scopus 로고
    • LIGAND: A versatile computerized approach for characterization of ligand-binding systems
    • Munson P. J. and Rodbard D. (1980) LIGAND: a versatile computerized approach for characterization of ligand-binding systems. Anal. Biochem. 107, 220-239.
    • (1980) Anal. Biochem. , vol.107 , pp. 220-239
    • Munson, P.J.1    Rodbard, D.2
  • 48
    • 0026779363 scopus 로고
    • Alternative splicing generates functionally distinct NMDA receptors
    • Nakanishi N., Axel R., and Schneider N. A. (1992) Alternative splicing generates functionally distinct NMDA receptors. Proc. Natl. Acad. Sci. USA 89, 8552-8556.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8552-8556
    • Nakanishi, N.1    Axel, R.2    Schneider, N.A.3
  • 49
    • 0026437728 scopus 로고
    • Molecular diversity of glutamate receptors and implications for brain function
    • Nakanishi S. (1992) Molecular diversity of glutamate receptors and implications for brain function. Science 258, 597-603.
    • (1992) Science , vol.258 , pp. 597-603
    • Nakanishi, S.1
  • 50
    • 0026501791 scopus 로고
    • Ethanol inhibition of N-methyl-D-aspartate-activated ion channel in rat hippocampal neurons is not competitive with Gly
    • Peoples R. W. and Weight F. F. (1992) Ethanol inhibition of N-methyl-D-aspartate-activated ion channel in rat hippocampal neurons is not competitive with Gly. Brain Res. 571, 342-344.
    • (1992) Brain Res. , vol.571 , pp. 342-344
    • Peoples, R.W.1    Weight, F.F.2
  • 52
    • 0025684618 scopus 로고
    • Gly site directed agonists reverse actions of ethanol at the N-methyl-D-aspartate receptor
    • Rabe C. S. and Tabakoff B. (1990) Gly site directed agonists reverse actions of ethanol at the N-methyl-D-aspartate receptor. Mol. Pharmacol. 38, 753-757.
    • (1990) Mol. Pharmacol. , vol.38 , pp. 753-757
    • Rabe, C.S.1    Tabakoff, B.2
  • 53
    • 0023820777 scopus 로고
    • 3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine and polyamines
    • 3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine and polyamines. J. Neurochem. 51, 830-836.
    • (1988) J. Neurochem. , vol.51 , pp. 830-836
    • Ransom, R.W.1    Stec, N.L.2
  • 54
    • 0025251626 scopus 로고
    • 3H]N-(1-[thienyl]cyclohexyl)piperidine binding by arcaine: Evidence for a shared spermidine-magnesium binding site
    • 3H]N-(1-[thienyl]cyclohexyl)piperidine binding by arcaine: evidence for a shared spermidine-magnesium binding site. Mol. Pharmacol. 38, 705-710.
    • (1990) Mol. Pharmacol. , vol.38 , pp. 705-710
    • Sacaan, A.I.1    Johnson, K.M.2
  • 55
    • 0025273692 scopus 로고
    • 3H]TCP binding to the NMDA receptor ionophore complex
    • 3H]TCP binding to the NMDA receptor ionophore complex. Mol. Pharmacol. 37, 572-577.
    • (1990) Mol. Pharmacol. , vol.37 , pp. 572-577
    • Sacaan, A.I.1    Johnson, K.M.2
  • 56
    • 0025357209 scopus 로고
    • The dose-response relationship for N-melhyl-D-aspartate currents in culture rat septal neurons: Effects of magnesium ion and 2-amino-5-phosphonovaleric acid
    • Shingai R., Ebina Y., Nagaoka S., and Harada K. (1990) The dose-response relationship for N-melhyl-D-aspartate currents in culture rat septal neurons: effects of magnesium ion and 2-amino-5-phosphonovaleric acid. Neurosci. Lett. 111, 183-188.
    • (1990) Neurosci. Lett. , vol.111 , pp. 183-188
    • Shingai, R.1    Ebina, Y.2    Nagaoka, S.3    Harada, K.4
  • 58
    • 0027405992 scopus 로고
    • Radioligand binding to the N-methyl-D-aspartate receptor/ionophore complex: Alterations by ethanol in vitro and by chronic in vivo ethanol ingestion
    • Snell L. D., Tabakoff B., and Hoffman P. L. (1993) Radioligand binding to the N-methyl-D-aspartate receptor/ionophore complex: alterations by ethanol in vitro and by chronic in vivo ethanol ingestion. Brain Res. 602, 91-98.
    • (1993) Brain Res. , vol.602 , pp. 91-98
    • Snell, L.D.1    Tabakoff, B.2    Hoffman, P.L.3
  • 59
    • 0028987601 scopus 로고
    • 3H]MK-801 binding associated with the N-methyl-D-aspartate receptor complex by acute ethanol in rat cortex and hippocampus in vitro
    • 3H]MK-801 binding associated with the N-methyl-D-aspartate receptor complex by acute ethanol in rat cortex and hippocampus in vitro. Alcohol. Clin. Exp. Res. 19, 305-313.
    • (1995) Alcohol. Clin. Exp. Res. , vol.19 , pp. 305-313
    • Spuhler-Phillips, K.1    Gonzalez, J.2    Randall, P.K.3    Leslie, S.W.4
  • 61
    • 0025191432 scopus 로고
    • Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists
    • Watkins J. C., Krogsgaard-Larsen P., and Honore T. (1990) Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. Trends Pharmacol. Sci. 11, 25-33.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 25-33
    • Watkins, J.C.1    Krogsgaard-Larsen, P.2    Honore, T.3
  • 63
    • 0025096750 scopus 로고
    • Ethanol inhibits NMDA-activated current but does not alter GABA-activated current in an isolated adult mammalian neuron
    • White G., Lovinger D. M., and Weight F. F. (1990) Ethanol inhibits NMDA-activated current but does not alter GABA-activated current in an isolated adult mammalian neuron. Brain Res. 507, 332-336.
    • (1990) Brain Res. , vol.507 , pp. 332-336
    • White, G.1    Lovinger, D.M.2    Weight, F.F.3
  • 64
    • 0025762248 scopus 로고
    • Sites for antagonism on the N-methyl-D-aspartate receptor channel complex
    • Wong E. H. F. and Kemp J. A. (1991) Sites for antagonism on the N-methyl-D-aspartate receptor channel complex. Annu. Rev. Pharmacol. Toxicol. 31, 401-425.
    • (1991) Annu. Rev. Pharmacol. Toxicol. , vol.31 , pp. 401-425
    • Wong, E.H.F.1    Kemp, J.A.2
  • 65
    • 0028047489 scopus 로고
    • A comparison of the effects of ethanol and the competitive glycine antagonist 7-chlorokynurenic acid on N-methyl-D-aspartic acid-induced neurotransmitter release from rat hipocampal slices
    • Woodward J. J. (1994) A comparison of the effects of ethanol and the competitive glycine antagonist 7-chlorokynurenic acid on N-methyl-D-aspartic acid-induced neurotransmitter release from rat hipocampal slices. J. Neurochem. 62, 987-991.
    • (1994) J. Neurochem. , vol.62 , pp. 987-991
    • Woodward, J.J.1
  • 66
    • 0025019986 scopus 로고
    • Ethanol inhibition of N-methyl-D-aspartate-stimulated endogenous dopamine release from rat striatal slices: Reversal by glycine
    • Woodward J. J. and Gonzales R. A. (1990) Ethanol inhibition of N-methyl-D-aspartate-stimulated endogenous dopamine release from rat striatal slices: reversal by glycine. J. Neurochem. 54, 712-715.
    • (1990) J. Neurochem. , vol.54 , pp. 712-715
    • Woodward, J.J.1    Gonzales, R.A.2


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