Trends in colonic drug delivery: A review

Indian Drugs

Volumn 33, Issue 1, 1996, Pages 1-10

  Rama Prasad, Y V ^a   Krishnaiah, Y S R ^a   Satyanarayana, S ^a  

^a ANDHRA UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BROMPHENIRAMINE; DEXAMETHASONE; DICLOFENAC; DOXORUBICIN; DRUG CARRIER; FLUOROURACIL; HYDROCORTISONE; IBUPROFEN; ISOSORBIDE; METOPROLOL; NICOTINE; NIFEDIPINE; NIMUSTINE; PREDNISOLONE; PRODRUG; SALAZOSULFAPYRIDINE; THEOPHYLLINE;

COLON; DRUG ABSORPTION; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG UPTAKE; ENTERITIS; GASTROINTESTINAL TRANSIT; HUMAN; INTRAGASTRIC DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; REVIEW; STOMACH EMPTYING;

EID: 0029935783     PISSN: 0019462X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (58)

1. Longer, M.A., Woodley, J.F. and Duncan, R. Comparison of the activities of rat small intestine and colon brush border membrane peptidases, Proc. Int. Symp. Controlled Release Bioact. Mater., 1989, 16, 225.
2. MacFarlane, G.T., Cummings, J.H., MacFarlane, S. and Gibson, G.R. Influence of retention time on degradation of pancreatic enzymes by colonic bacteria grown in a 3-stage continuous culture system, J. Appl. Bacteriol., 1989, 67, 521.
3. Digenis, G.A. and Sandefer, E. Gamma Scintigraphy and neutron activation techniques in the in vivo assessment of orally administered dosage forms. Crit. Rev. Ther. Drug Carrier Syst., 1991, 7, 309.
4. Taniguchi, K., Muranishi, S. and Sezaki, H. Enhanced intestinal permeability through macromolecules. II. Improvement of the large intestinal absorption of heparin by lipid-surfactant mixed micelles in rat. Int. J. Pharm., 1980, 4, 219.
5. Mackay, M. and Tomlinson, E. Colonic delivery of therapeutic peptides and proteins. In: Colonic Drug Absorption and Metabolism. Ed. Bieck, P., Dekker, New York, 1993, 159.
6. Hardy, J.G. Colonic transit and drug delivery. In: Drug Delivery to the Gastrointestinal Tract Eds. Hardy, J.G., David, S.S. and Wilson, C.G., Ellis Horwood, Chichestea, 1989, 75.
7. Davis, S.S., Stockwell, A.F., Taylor, M.J. et al. The effect of density on gastric emptying of single unit and multiple unit dosage forms. Pharm. Res., 1986, 3, 208.
8. Davis, S.S., Hardy, J.G. and Fara, J.W. Tarnsit of Pharmaceutical dosage forms through the small intestine Gut, 1986, 27, 886.
9. Grubur, P., Longer, M.A. and Robinson, J. Some biological issues in oral controlled drug delivery. Adv. Drug Del. Rev., 1987, 1, 1.
10. Metcalf, A.M., Philips, S.F., Zinsmeister, A.R. et al. Simplified assessment of segmental colonic transit. Gastroenterology, 1987, 92, 40.
11. Parker, G., Wilson, G.G. and Hardy, J.G. The effect of capsule size and density of transit through the proximal colon. J. Pharm. Pharmacol., 1988, 40, 376.
12. Enack, P., Merlin, V., Erckenbrecht, J.F. and Wienbeak, M. Stress effects on gastrointestinal transit in the rat. Gut, 1989, 30, 455.
13. Cann, P.A., Read, N.W., Brown, C. et al. Irritable bowel syndrome: Relationship of disorders in the transit of a single solid meal to symptom patterns, Gut, 1983, 24, 405.
14. Simon, G.L. and Gorbach, S.L. Intestinal flora in health and disease. Gastroenterology, 1984, 86, 174.
15. Rowland, I.R Factors affecting metabolic activity of the intestinal microflora Drug Metabol. Rev., 1988, 19, 243.
16. Mrsny, R.J. The colon as a site for drug delivery. J. Controlled Rel , 1992, 22, 15.
17. Nubuchi, J.J., Aramaki, Y. and Tsuchiya, S. Binding of antibiotics to rat intestinal mucin. Int. J. Pharm., 1986, 30, 181
18. Powell, D.W. Barrier function of epithelia. Am. J. Physiol., 1981, 241, G275.
19. Rhodes, J. and Thomas, G. Nicotine treatment in ulcerative colitis, current status. Drugs, 1995, 49, 157.
20. Fara, J.W. Colonic drug absorption and metabolism, In: Novel Drug Delivery and its Therapeutic Application., Eds. Prescott, L.F. and Nimmo, W.S., Wiley, Chichester, 1989, 103.
21. Osika, I., Porter, P.A., Borchardt, R.T. et al. In vitro drug absorption models I. Brush border membrane vesicles, isolated mucosal cells and everted intestinal rings: characterisation and salicylate accumulation. Pharm. Res., 1985, 2, 284.
22. Audus, K.L., Bartel, R.L., Hidalgo, I.J. et al. The use of cultured epithelial endothelial cells for drug transport and metabolism studies. Pharm. Res., 1990, 7, 435.
23. Tomita, T., Hayashi, M., Toshihane, H. et al. Enhancement of colonic drug absorption by the transcellular permeation route.Pharm. Res., 1988, 5, 786.
24. Riad, L.E. and Sawchuk, R.J. Effect of polyethyleneglycol 400 on the intestinal permeability of carbamazepine in the rabbit. Pharm. Res., 1991, 8, 481.
25. Suzuka, T., Furuya, A., Kamada, A. et al. Effects of phenothiazines and N-(6-aminohexyl)-5-chloro-1-napthalene sulphonomide on rat colonic absorption of cefmetazole. J. Pharmacobio-Dyn., 1986, 9, 460.
26. Tolls, R.M., Imamovic, M.A. and McGarry, M.P. Enteral perfusion in the pig. Lab. Anim. Sci., 1986, 36, 400.
27. Fujii, T., Yanagisawa, J. and Nakayama, F. Absorption of bile acids in dogs as determined by portal sampling: Evidence for colonic absorption of bile acid conjugates. Digestion, 1988, 41, 207.
28. Gleiter, C.H., Antonin, K.H., Bieck, P. et al. Colonoscopy in the investigation of drug absorption in healthy volunteers. Gastrointest Endosc , 1985, 31, 71.
29. Winter, H.S., Hendren, R.B., Fox, C.H. et al Human intestine matures as nude mice xenograft. Gastroenterology, 1991, 100, 89.
30. Fix, J.A. Absorption enhancing agents for the Gl system. J.Controlled Rel., 1987, 6, 151.
31. Muranishi, S., Yoshikawa, H. and Sezaki, H. Absorption of 5-fluorouracil from various regions of the gastrointestinal tract in rat: Effect of mixed micelles. J. Pharmacobio-Dyn., 1979, 2, 286.
32. Muranishi, S., Yoshikawa, H. and Sezaki, H. Enhanced intestinal permeability to macromolecules II. Improvement of the large intestinal absorption of heparin by lipid - surfactnat mixed micelles in rat. Int. J. Pharm., 1980, 4, 219.
33. Yoshikawa, H., Muranishi, S., Kato, C. et al. Bifunctional delivery system for selective transfer of bleomycin into lymphatics via enteral route. Int. J. Pharm., 1981, 8, 291.
34. Schacht, E., Callant D. and Verstrasct, W. Synthesis and evaluation of polymeric prodrugs of 5-aminosalicylic acid,. Proc. Int. Symp. Controlled Release Bioact. Mater., 1991, 18, 686.
35. Kopeckova, P., Rathi, R., Takada, S. et al. Bioadhesive N-(2-hydroxypropyl) methacrylamide copolymers for colon-specific drug delivery. J. Controlled Rel., 1984, 28, 211.
36. Friend, D.R. Glycosides in colonic drug delivery. In: Oral Colon-Specific Drug Delivery, Friend, D.R., CRC Press, London, 1992, 153.
37. Friend, D.R. and Chang, G.W. A colon-specific drug delivery system based on drug glycosides and glycosidases of colonic bacteria. J. Med. Chem., 1984, 27, 261.
38. Friend, D.R. and Chang, G.W. Drug glycosides: Potential prodrugs for colon-specific drug delivery. J. Med. Chem.., 1985, 28, 51.
39. Harboe, E., Larsen, C., Johansen, M. and Olesen, H.P. Macromolecular prodrugs. XV. Colon-targeted delivery-Bioavailability of naproxen from orally administered dextran-naproxen ester prodrugs varying in molecular size in the pig. Pharm. Res., 1989, 6, 919.
40. Harboe, E., Larsen, C., Johansen, M. and Olesen, H.P. Macromolecular prodrugs. XVI. Colon-targeted delivery-Comparison of rate of release of naproxen from dextran ester prodrugs in homogenates of various segments of the pig gastrointestinal (Gl) tract. Pharm. Res., 1989, 6, 995.
41. McLeod, A.D., Friend, D.R. and Tozer, T.N. Synthesis and chemical stability of glucocorticoid-dextran esters: Potential prodrugs for colon-specific delivery. Int. J. Pharm., 1993, 92, 105.
42. McLeod, A.D., Friend, D.R. and Tozer, T.N. Glucocorticoid-dextran conjugates as potential prodrugs for colon-specific delivery: Hydrolysis in rat gastrointestinal tract contents. J. Pharm. Sci., 1994, 83, 1284.
43. Thomas, P., Richards, D., Richards, A. et al. Absorption of delayed release prednisolone in ulcerative colitis and Crohn's disease. J. Pharm. Pharmacol., 1985, 37, 757.
44. Touitou, E. and Rubinstein, A. Targeted enteral delivery of insulin to rats. Int. J. Pharm., 1986, 30, 95.
45. Van Saene, J.J.M., Van Saene, H.F.K., Geitz, J.N. et al. Quinolones and colonisation resistance in human volunteers. Pharm. Weekbl Sci. Ed., 1986, 8, 67.
46. Ashford, M., Fell, J.T., Attwood, D. et al. An in vivo investigation into the suitability of pH dependent polymers for colonic targeting. Int. J. Pharm., 1993, 95, 193.
47. Van den Mooter, G., Samyn, C. and Kinget, R. Azo polymers for colon-specific drug delivery. II: Influence of the type of azo polymer on the degradation by intestinal microflora. Int. J. Pharm., 1993, 97, 133.
48. Saffran, M., Field, J.B., Pana, J. et al. Oral insulin in diabetic dogs. J. Endocrinol., 1991, 131, 267.
49. Saffran, M., Bedra, C., Kumar, G.S. and Neckers, D.C. Vasopressin: A model for the study of the effects of additives on the oral and rectal administration of peptide drugs. J. Pharm. Sci., 1988, 77, 33.
50. Lehmann, K.O.R. and Dreher, K.D. Methacrylate-galactomannan coating for colon-specific drug delivery. Proc. Int. Symp. Controlled Release Bioact. Mater., 1991, 18, 331.
51. Ashford, M., J.T., Attwood, D. et al. An evaluation of pectin as a carrier for drug targeting to the colon. J.Controlled Rel., 1993, 26, 213.
52. Ashford, M., Fell, J.T., Attwood, D. et al. Studies on pectin formulations for colonic drug delivery. J. Controlled Rel., 1994, 30, 225.
53. Rubinstein, A., Radai, R., Ezra, M. et al. In vivo evaluation of calcium pectinate: A potential colon-specific drug delivery carrier. Pharm. Res., 1993, 10, 258.
54. Rubinstein, A., Nakar, D. and Sintov, A. Chondroitin sulphate: A potential biodegradable carrier for colon-specific drug delivery. Int. J. Pharm., 1992, 84, 141.
55. Rubinstein, A., Nakar, D. and Sintov, A. Colonic drug Delivery: Enhanced release of indomethacin from cross-linked chondroitin matrix in rat caecal content. Pharm. Res., 1992, 9, 276.
56. French, D.L. and Mauger, J.W. Evaluation of the physico-chemical properties and dissolution characteristics of mesalazine. Relevance to controlled intestinal drug delivery. Pharm. Res., 1993, 10, 1285.
57. Kopecek, J. The potential of water soluble polymeric earners in targeted and site-specific drug delivery. J. Controlled Rel., 1990, 11, 279.
58. Friend, D.R., Philips, S. and Tozer, T.N. Colon-specific drug delivery from a glucoside prodrug in the guinea pig. Efficacy study. J. Controlled Rel., 1991, 15, 47.