Putative steroid binding domain of the human mineralocorticoid receptor, expressed in E. coli in the presence of heat shock proteins shows typical native receptor characteristics

Journal of Steroid Biochemistry and Molecular Biology

Volumn 57, Issue 1-2, 1996, Pages 43-50

  Jalaguier, Stéphan ^a   Mesnier, Danielle ^a   Léger, Jean J ^a   Auzou, Gilles ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; CORTICOSTERONE; GLUTATHIONE TRANSFERASE; HEAT SHOCK PROTEIN; HYBRID PROTEIN; MALTOSE BINDING PROTEIN; MINERALOCORTICOID RECEPTOR; PROGESTERONE; SPIRONOLACTONE;

ARTICLE; BINDING SITE; DRUG RECEPTOR BINDING; ESCHERICHIA COLI; GENE EXPRESSION; HUMAN; PROTEIN DOMAIN;

ESCHERICHIA COLI; ORYCTOLAGUS CUNICULUS;

EID: 0029935336     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-0760(95)00250-2     Document Type: Article

References (29)

1. Yamamoto K. R.: Steroid receptor regulated transcription of specific genes and gene networks. A. Rev. Genet. 19 (1985) 209-252.
2. Hollenberg S. M., Weinberger C., Ong E. S., Cerelli G., Oro A., Lebo R., Thompson E. B., Rosenfeld M. G. and Evans R. M.: Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature 318 (1985) 635-641.
3. Evans R. M.: The steroid and thyroid hormone receptor super-family. Science 240 (1988) 889-895.
4. Arriza J. L., Weinberger C., Cerelli G., Glaser T. M., Handelin B. L., Housman D. E. and Evans R. M.: Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science 237 (1987) 268-275.
5. Hollenberg S. M., Giguere V., Segui P. and Evans R. M.: Co-localization of DNA-binding and transcriptional activation function in the human glucocorticoid receptor. Cell 49 (1987) 39-46.
6. Alnemri E. S., Maksymowych A. B., Robertson N. M. and Litwack G. : Overexpression and characterization of the human mineralocoritcoid receptor. J. Biol. Chem. 266 (1991) 18,072-18,081.
7. Binart N., Lombes M., Rafestin-Oblin M. E. and Beaulieu E. E.: Characterization of human mineralocorticosteroid receptor expressed in the baculovirus system. Proc. Natn. Acad. Sci. U.S.A. 88 (1991) 10,681-10,685.
8. Nemoto T., Ohara-Nemoto Y. and Ota M.: Association of the 90-kDa heat shock protein does not affect the ligand-binding ability of androgen receptor. J. Steroid Biochem. Molec. Biol. 42 (1992) 803-812.
9. Joab I., Radanyi C., Renoir M., Buchou T., Catelli M. G., Binart N., Mester J. and Baulieu E. E.: Common non-hormone binding component in non transformed chick oviduct receptors of four steroid hormones. Nature 308 (1984) 850-853.
10. Rexin M., Busch W. and Gehring U.: Structure of the glucocorticoid receptor in the absence of hormone. J. Biol. Chem. 266 (1991) 24,601-24,605.
11. Pratt W. B.: The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptors. J. Biol. Chem. 268 (1993) 21,455-21,458.
12. Caamaño C. A., Morano M. I., Patel P. D., Watson S. J. and Akil U.: A bacterially expressed mineralocorticoid receptor is associated in vitro with the 90-kilodalton heat shock protein and shows typical hormone- and DNA-binding characteristics. Biochemistry 32 (1993) 8589-8595.
13. Bresnick E. H., Dalman F. C., Sanchez E. R. and Pratt W. B.: Evidence that the 90 kDa heat shock protein is necessary for the steroid binding conformation of the L cell glucocorticoid receptor. J. Biol. Chem. 264 (1989) 4992-4997.
14. Dalman F. C., Bresnick E. H., Patel P. D., Pardew G. H., Watson S. J. and Pratt W. B.: Direct evidence that the glucocorticoid receptor binds to hsp90 at or near the termination of receptor translation in vitro. J. Biol. Chem. 264 (1989) 19,815-19,819.
15. Smith D. F., Stensgard B. A., Welch W. J. and Toft D. O.: Assembly of progesterone receptor with heat shock proteins and receptor activation are ATP mediated events. J. Biol. Chem. 267 (1992) 1350-1356.
16. Sullivan W. P. and Toft D. O.: Mutational analysis of hsp90 binding to the progesterone receptor. J. Biol. Chem. 268 (1993) 20,373-20,379.
17. Eul J., Meyer M. E., Tora L., Bocquel M. T., Quirin-Stricker C., Chambon P. and Gronemeyer H.: Expression of active hormone and DNA-binding domains of the chicken progresterone receptor in E. coli. EMBO J. 8 (1989) 83-90.
18. Power R. F., Conneely O. M., McDonnell D. P., Clark J. H., Butt T. R., Schrader W. T. and O'Malley B. W.: High level expression of a truncated chicken progresterone receptor in Escherichia coli. J. Biol. Chem. 265 (1990) 1419-1424.
19. Jausons-Loffreda N., Balaguer P., Auzou G. and Pons M.: Development of specific bioluminescent in vitro assays for selecting potential antimineralocorticoids. J. Steroid. Biochem. Molec. Biol. 49 (1994) 31-38.
20. Fankhauser C. P., Briand P. A. and Picard D.: The hormone binding domain of the mineralocorticoid receptor can regulate heterologous activities in cis. Biochem. Biophys. Res. Commun. 200 (1994) 195-201.
21. Ohara-Nemoto Y., Strömstedt P.-E., Dahlman-Wright K., Nemoto T., Gustafsson J.-A. and Carlstedt-Duke J.: The steroid-binding properties of recombinant glucocorticoid receptor: a putative role for heat shock protein hsp90. J. Steroid. Biochem. Molec. Biol. 37 (1990) 481-490.
22. Cadepond F., Schweizer-Groyer G., Segard-Maurel I., Jibard N., Hollenberg S. M., Giguère V., Evans R. M. and Baulieu E. E.: Heat shock protein 90 as a critical factor in maintaining glucocorticoid receptor in a nonfunctional state. J. Biol. Chem. 266 (1991) 5834-5841.
23. Lowry O. H., Rosebrough N. J., Farr A. L. and Randall J.: Protein measurement with Folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275.
24. Rafestin-Oblin M. E., Couette B., Radanyi C., Lombes M. and Baulieu E. E.: Mineralocorticosteroid receptor of the chick intestine. J. Biol. Chem. 264 (1989) 9304-9309.
25. Couette B., Lombes M., Baulieu E. E. and Rafestin-Oblin M. E.: Aldosterone antagonists destabilize the mineralocorticosteroid receptor. Biochem. J. 282 (1992) 697-702.
26. Jakob U. and Buchner J.: Assisting spontaneity: the role of hsp90 and small hsps as molecular chaperones. TIBS 19 (1994) 205-211.
27. Becker J. and Craig A.: Heat-shock proteins as molecular chaperones. Eur. J. Biochem. 219 (1994) 11-23.
28. Cadepond F., Binart B., Chambraud B., Jibard N., Schweizer-Groyer G., Segard-Maurel I. and Baulieu E. E.: Interaction of glucocorticosteroid receptor and wild-type or mutated 90-kDa heat shock protein coexpressed in baculovirus-infected Sf9 cells. Proc. Natn. Acad. Sci. 90 (1993) 10,434-10,438.
29. Spence J. and Georgopoulos C.: Purification and properties of the Escherichia coli heat shock protein, HtpG. J. Biol. Chem. 264 (1989) 4398-4403.