Targeting of porcine pancreatic phospholipase A2 to human platelets Introduction of an RGD sequence and acyl-group by chemical modification

European Journal of Biochemistry

Volumn 238, Issue 1, 1996, Pages 70-76

  Bekkers, Augustinus C A P A ^a   Slotboom, Arend J ^a   Van Willigen, Gijshert ^b   Akkerman, Jan Willem N ^b   Verheij, Hubertus M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Enzyme targetting; Glycoprotein IIb IIIa; Human platelets; Membrane hydrolysis; Phospholipase A2; Phospholipid hydrolysis

Indexed keywords

SUIDAE;

FIBRINOGEN RECEPTOR; LAURIC ACID; PHOSPHOLIPASE A2; PHOSPHOLIPID; THROMBIN;

ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME MODIFICATION; HUMAN; HUMAN CELL; HYDROLYSIS; MEMBRANE BINDING; PRIORITY JOURNAL; THROMBOCYTE; THROMBOCYTE ACTIVATION;

ACYLATION; AMINO ACID SEQUENCE; ANIMALS; ARACHIDONIC ACID; BLOOD PLATELETS; HUMANS; INDICATORS AND REAGENTS; LAURIC ACIDS; LIPOPROTEINS; MEMBRANE LIPIDS; MOLECULAR SEQUENCE DATA; PANCREAS; PEPTIDES; PHOSPHOLIPASES A; PHOSPHOLIPIDS; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

EID: 0029934695     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.0070q.x     Document Type: Article

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