Perioperative antimicrobial prophylaxis in neurosurgery: Clinical trial of systemic flomoxef administration and saline containing gentamicin for irrigation

Neurologia Medico-Chirurgica

Volumn 36, Issue 6, 1996, Pages 370-376

  Yamamoto, Masaaki ^a   Jimbo, Minoru ^a   Ide, Mitsunobu ^a   Tanaka, Noriko ^a   Umebara, Yutaka ^a   Hagiwara, Shinji ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

antibiotic prophylaxis; flomoxef; gentamicin; meningitis; neurosurgery; postoperative infection

Indexed keywords

FLOMOXEF; GENTAMICIN;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC PROPHYLAXIS; ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; FEMALE; HUMAN; INFECTION CONTROL; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; MENINGITIS; POSTOPERATIVE INFECTION;

EID: 0029934240     PISSN: 03872572     EISSN: None     Source Type: Journal    
DOI: 10.2176/nmc.36.370     Document Type: Article

References (47)

1. Barker FG: Efficacy of prophylactic antibiotics for craniotomy: A meta-analysis. Neurosurgery 35: 484-492, 1994
2. Blomstedt GC: Results of trimethoprim-sulfamethoxazole prophylaxis in ventriculostomy and shunting procedures: A double-blind randomized trial. J Neurosurg 62: 694-697, 1985
3. Blomstedt GC, Kyttä J: Results of a randomized trial of vancomycin prophylaxis in craniotomy. J Neurosurg 69: 216-220, 1988
4. Brown EM: Antimicrobial prophylaxis in neurosurgery. Br J Neurosurg 1: 159-161, 1987
5. Brown EM: Antimicrobial prophylaxis in neurosurgery. J Antimicrob Chemother 31 (Suppl B): 49-63, 1993
6. Bullock R, van Dellen JR, Ketelbey W, Reinach SG: A double-blind placebo-controlled trial of perioperative prophylactic antibiotics for elective neurosurgery. J Neurosurg 69: 687-691, 1988
7. Cartmill TDI, AlZahawi MF, Sisson PR, Ingham HR, Gould FK, Crone PB, Betty MJ, Crawford PJ, Kalbag RM, Mendelow AD, Sengupta RP: Five days versus one day of penicillin as prophylaxis in elective neurosurgical operations. J Hosp Infect 14: 63-68, 1989
8. Choux M, Genitori L, Lang D, Lena G: Shunt implantation: Reducing the incidence of shunt infection. J Neurosurg 77: 875-880, 1992
9. Curse PJE, Foord R: A five-year prospective study of 23,649 surgical wounds. Arch Surg 107: 206-210, 1973
10. Dempsey R, Rapp RP, Young B, Johnston S, Tibbs P: Prophylactic parenteral antibiotics in clean neurosurgical procedures: A review. J Neurosurg 69: 52-57, 1988
11. Djindjian M, Lepresle E, Homs J-B: Antibiotic prophylaxis during prolonged clean neurosurgery: Results of a randomized double-blind study using oxacillin. J Neurosurg 73: 383-386, 1990
12. Gaillard T, Gilsbach JM: Intra-operative antibiotic prophylaxis in neurosurgery: A prospective, randomized, controlled study on cefotiam. Acta Neurochir (Wien) 113: 103-109, 1991
13. Geraphty J, Feely M: Antibiotic prophylaxis in neurosurgery. A randomized controlled trial. J Neurosurg 60: 724-726, 1984
14. Goldstein A, Raggueneau JL, Kind A, Moret G, George B: Prophylactic antibiotherapy in neurosurgery. Agressologie 24: 233-236, 1983
15. Goto S, Ogawa M, Kaneko Y, Miyazaki S, Tsuji A, Kuwahara S: Bacteriological evaluation of a new oxacephem antibiotic, 6315-S (flomoxef). Nihon Kagakuryoho Gakkai Zasshi 35 (S-1): 1-21, 1987 (in Japanese)
16. Haines SJ: Efficacy of antibiotic prophylaxis in clean neurosurgical operations. Neurosurgery 24: 401-405, 1989
17. Haines SJ: Antibiotic prophylaxis in neurosurgery: The controlled trials. Neurosurg Clin N Am 3: 355-358, 1992
18. Haines SJ, Goodman ML: Antibiotic prophylaxis of postoperative neurosurgical wound infection. J Neurosurg 56: 103-105, 1982
19. Haines SJ, Walters BC: Antibiotic prophylaxis for cerebrospinal fluid shunts: A metaanalysis. Neurosurgery 34: 87-92, 1994
20. Ingham HR, Kalbag RM, Sisson PR, Allcutt DA, Betty MJ, Crawford PJ, Gillham NR, Hankinson J, Sengupta RP, Strong AJ, Sinar EJ, Crone PB, Gillham M, Gould FK, Hudson SJ, Wardle JK, Cartmill TDI, Strokes ER: Simple peroperative antimicrobial chemoprophylaxis in elective neurosurgical operations. J Hosp Infect 12: 225-233, 1988
21. Inoue K, Fukamizu H, Yamanaka K, Mita H, Tomita K, Usui A: Transfer of flomoxef of skin tissue in the field of plastic surgery. Kiso To Rinsho 24: 4117-4119, 1994 (in Japanese)
22. Iyobe S, Kubota T, Mitsuhashi S: In vitro and in vivo antibacterial activities of 6315-S (flomoxef). Nihon Kagakuryoho Gakkai Zasshi 35 (S-1): 22-32, 1987 (in Japanese)
23. Kitamura K, Shimizu T, Abe H, Suzuki J, Tanaka R, Nagai H, Yamamoto S, Handa H, Nishimoto A, Matsuoka K, Mod K: Clinical studies of cefoperazone in neurosurgery. Jpn J Antibiot 39: 63-74, 1986 (in Japanese)
24. Kumagai N, Wakao T, Tamura M: Postoperative infections at Yamanashi Central Hospital, in Mori K (ed): 8th Congress on Specific Topics in Neurosurgery. Tokyo, No-shinkei-geka Tokubetsumondai Konwakai, 1975, pp 11-15 (in Japanese)
25. Malis LI: Prevention of neurosurgical infection by intraoperative antibiotics. Neurosurgery 5: 339-343, 1979
26. Mollman HD, Haines SJ: Risk factors for postoperative neurosurgical wound infection. A case control study. J Neurosurg 64: 902-906, 1986
27. Nakata M, Higa Y, Mukawa J, Sakuta O, Ishikawa Y, Okuyama K, Terada Y, Samura H, Tomita N: Clinical study on flomoxef in the neurosurgical field: Focused on the relation between cerebrospinal fluid transfer and blood brain barrier lesions. Kagakuryoho No Ryoiki 10: 943-948, 1994 (in Japanese)
28. Oizumi K, Saito A, Nagahama F, Takebe K, Tamura M, Hayashi I, Watanabe A, Aonuma S, Konno K: 6315-S (flomoxef) in respiratory tract infections. Nihon Kagakuryoho Gakkai Zasshi 35: 541-561, 1987 (in Japanese)
29. Quadery LA, Medley AV, Miles J: Factors affecting the incidence of wound infection in neurosurgery. Acta Neurochir (Wien) 39: 133-141, 1977
30. Quartey GRC, Polyzoidis K: Intraoperative antibiotic prophylaxis in neurosurgery: A clinical study. Neurosurgery 8: 669-671, 1981
31. Reale F, Biancotti R, De Falco D, Gambacorta D: Antibiotic prophylaxis in neurosurgery. Study comparing two groups of patients with and without treatment. Acta Neurochir (Wien) 86: 75-78, 1987
32. Savitz MH, Katz SS: Prevention of primary wound infection in neurosurgical patients: A 10-year study. Neurosurgery 18: 685-688, 1986
33. Sawa K, Aoki M, Konno H, Kobayashi T, Watanabe K, Ueno T: In vitro and in vivo antimicrobial activity of 6317-S (flomoxef) against anaerobic bacteria. Nihon Kagakuryoho Gakkai Zasshi 35 (S-1): 44-56, 1987 (in Japanese)
34. Shapiro M, Wald U, Simchen E, Pomeranz S, ZagZag D, Michowiz SD, Samuel-Cahn E, Wax Y, Shuval R, Kahane Y, Sacks T, Shalit M: Randomized clinical trial of intra-operative antimicrobial prophylaxis of infection after neurosurgical procedures. J Hosp Infect 8: 283-295, 1986
35. Tenney JH, Vlahov D, Salcman M, Ducker TB: Wide variation in risk of wound infection following clean neurosurgery. Implications for perioperative antibiotic prophylaxis. J Neurosurg 62: 243-247, 1985
36. Tokoro K, Chiba Y, Tsubone K: Late infection after cranioplasty. Review of 14 cases. Neurol Med Chir (Tokyo) 29: 196-201, 1989
37. Tomihara M, Tanaka S: Clinical effect on flomoxef concentration of bone tissue. Kiso To Rinsho 24: 3375-3378, 1990 (in Japanese)
38. Urciuoli R, Russo GL, Zeme S, Lanotte M: Antibiotic prophylaxis of post-operatory infections in neurosurgery. Agressologie 24: 237-238, 1983
39. van Ek B, Dijkmans BAC, van Dulken H, Mouton RP, van Furth R: Efficacy of cloxacillin prophylaxis in craniotomy: A one year follow-up study. Scand J Infect Dis 23: 617-623, 1991
40. van Ek B, Dijkmans BAC, van Dulken H, van Furth R: Antibiotic prophylaxis in craniotomy: A prospective double-blind placebo-controlled study. Scand J Infect Dis 20: 633-639, 1988
41. Winkler D, Rehn H, Freckmann N, Nowak G, Herrmann HD: Clinical efficacy of perioperative antimicrobial prophylaxis in neurosurgery: A prospective randomized study involving 159 patients. Chemotherapy 35: 304-312, 1989
42. Yamamoto M, Jimbo M, Ide M, Tanaka N, Umebara Y, Hagiwara S: Postoperative neurosurgical infection and antibiotic prophylaxis. Neurol Med Chir (Tokyo) 32: 72-79, 1992
43. Yamamoto M, Jimbo M, Ide M, Tanaka N, Umebara Y, Hagiwara S, Takeyama E, Koshimizu K, Takeyama E, Imanaga H, Ishii T: Flomoxef prophylaxis in neurosurgical surgery. Kagakuryoho No Ryoiki 10: 937-942, 1994 (in Japanese)
44. Yamashita J, Waga S, Ishikawa M, Nagasawa S, Handa H, Murayama R: Postoperative infections in neurosurgery, in Mori K (ed): 8th Congress on Specific Topics in Neurosurgery. Tokyo, No-shinkeigeka Tokubetsumondai Konwakai, 1975, pp 1-9 (in Japanese)
45. Yamaura A, Sato M, Meguro K, Nakamura T, Uemura K, Makino H: Cranioplasty following decompressive craniotomy. Analysis of 300 cases. No Shinkei Geka 5: 345-353, 1977 (in Japanese)
46. Young RF, Lawner PM: Perioperative antibiotic prophylaxis for prevention of postoperative neurosurgical infections: A randomized clinical trial. J Neurosurg 66: 701-705, 1987
47. Yura J, Nishi H, Shibata K, Takagi T: Antibiotic use for infections of central nervous system. No Shinkei Geka 5: 909-918, 1977 (in Japanese)