Double-blind evaluation of ritodrine sustained release for oral maintenance of tocolysis after active preterm labour

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 103, Issue 7, 1996, Pages 702-705

  Holleboom, C A G ^a   Merkus, J M W M ^b   van Elferen, L W M ^c   Keirse, M J N C ^d  

^a MEDICAL CENTER HAAGLANDEN   (Netherlands)

^b Maria Hospital TIlburg   (Netherlands)

^c Solvay Pharmaceuticals Inc   (Netherlands)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; RITODRINE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; FEMALE; FETUS; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PREMATURE LABOR; PRIORITY JOURNAL; SUSTAINED RELEASE PREPARATION; TOCOLYSIS; TREMOR;

ADMINISTRATION, ORAL; ADULT; DELAYED-ACTION PREPARATIONS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; OBSTETRIC LABOR, PREMATURE; PREGNANCY; PREGNANCY, MULTIPLE; RITODRINE; TOCOLYTIC AGENTS; TREATMENT OUTCOME;

EID: 0029933966     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/j.1471-0528.1996.tb09841.x     Document Type: Article

References (20)

1. Creasy RK, Golbus MS, Laros RK Jr, Parer JT, Roberts JM. Oral ritodrine maintenance in the treatment of preterm labor. Am JObstet Gynecol 1980; 137:212-219.
2. Brown SM, Tejani NA. Terbutaline sulfate in the prevention of recurrence of premature labor. Obster Gynecol 1981; 57:22-25.
3. Smit DA. Efficacy of orally administered ritodrine after initial intravenous therapy [MD thesis]. Limburg, The Netherlands : University of Limburg, 1983.
4. Keirse MJNC, Grant A, King JF. Preterm labour. In: Chalmers I, Enkin M, Keirse MJNC, editors. Efective Care in Pregnancy and Childbirth. Oxford : Oxford University Press, 1989: 694-745.
5. Cabrol D. The therapeutic value of prophylactic and maintenance treatment in preterm labour. Res Clin Forums 1994; 16:127-138.
6. Schiff E, Sivan E, Terry S et al. Currently recommended oral regimens for ritodrine tocolysis result in extremely low plasma levels. Am J Obster Gynecol 1993; 169:1059-1064.
7. Essed GGM, Struyker, Boudier HAJ, van Zijl JAWM. Bio-pharmaceutical aspects of ritodrine retard in pregnant women. Arch Int Pharmacodyn 1988; 293:295-300.
8. Witter FR, Benedetti TJ, Petty BG, Feldman AM, Traill TA, Anderson J. Phannacodynamics and tolerance of oral sustained release ritodrine. Am J Obster Gynecol 1988; 159:690-695.
9. Holleboom CAG, Merkus JMWM, van Elferen LWM, Keirse MJNC. Randomised comparison between a loading and incremental dose model for ritodrine administration in preterm labour. Br J Obstet Gynaecol 1996; 103:695-701.
10. Gardner MJ, Altman DG. Calculating confidence intervals for proportions and their differences. In: Gardner MJ, Altman, DG, editors. Statistics with Confidence. London : British Medical Journal, 1989: 28-33.
11. King JF, Grant A, Keirse MJNC, Chalmers I. Betamimetics in preterm labour: a pooled analysis of the randomised controlled trials. Br J Obstet Gynaecol 1988; 95:211-222.
12. Canadian Preterm Labor Investigators Group. Treatment of preterm labor with the beta-adrenergic agonist ritodrine. N Engl J Med 1992; 327:308-312.
13. Keirse MJNC. Betamimetic drugs in the prophylaxis of preterm labour: extent and rationale of their use. Br J Obstet Gynaecol 1984; 91:431-437.
14. Lamont RF. Clinical perspectives on current opinion for treatment strategy. Res Clin Forums 1994; 16:139-154.
15. Berg G, Andersson RG, Ryden G. Beta-adrenergic receptors in human myometrium during pregnancy: changes in the number of receptors after beta-mimetic treatment. Am J Obstet Gynecol 1985; 151:392-396.
16. Schneider H. Pharmacological intervention in pre-term labour. Res Clin Forums 1994; 16:59-87.
17. Gandar R, de Zoeten LW, van der Schoot, JB. Serum level of ritodrine in man. Eur J Clin Pharmacul 1980; 17:117-122.
18. Smit DA, Essed GGM, de Haan J. Serum levels of ritodrine during oral maintenance therapy. Gynecol Obstet Invest 1984; 18:105-112.
19. Essed GGM, de Haan J, Struyker, Boudier HAJ, van Elferen LWM. A new administration form of ritodrine - ritodrine plasmalevels with sustained-release capsules in a steady-state. Gynecol Obstet Invest 1987; 23:10-15.
20. Baumgarten K, Griiber W. Tokolyse-index. In: Dudenhausen JW, Saling, E, editors. Perinatale Medizin. Stuttgart : Thieme, 1974: 58-59.