Treatment of ischaemic digital ulcers and prevention of gangrene with intravenous iloprost in systemic sclerosis

Acta Dermato-Venereologica

Volumn 76, Issue 3, 1996, Pages 236-238

  Zachariae, Hugh ^a   Halkier Sørensen, Lars ^a   Bjerring, Peter ^a   Heickendorff, Lene ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

bloodflow; endothelin; prostaglandin analogue

Indexed keywords

ENDOTHELIN; ILOPROST;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; FEMALE; FLUSHING; FOOT ULCER; GANGRENE; HEADACHE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; NAUSEA; PRIORITY JOURNAL; RAYNAUD PHENOMENON; SYSTEMIC SCLEROSIS; TREATMENT OUTCOME; VASCULITIS;

ADULT; AGED; ENDOTHELINS; FEMALE; FINGERS; GANGRENE; HUMANS; ILOPROST; INFUSIONS, INTRAVENOUS; ISCHEMIA; MALE; MIDDLE AGED; RAYNAUD DISEASE; SCLERODERMA, SYSTEMIC; ULCER; VASODILATOR AGENTS;

EID: 0029933835     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Rademaker M, Cooke E, Almond N, Beacham J, Smith R, Mant T, et al. Comparison of intravenous infusions of iloprost and oral niphedipine in treatment of Raynaud's phenomenon in patients with systemic sclerosis: a double-blind randomized study. BMJ 1989; 298: 561-564.
2. Wigley F, Seibold J, Wise R, McCloskey D, Dole W. Intravenous iloprost treatment of Raynaud's phenomenon and ischemic ulcers secondary to systemic sclerosis. J Rheum 1992; 19: 1407-1414.
3. Belch J, Newman P, Drury J, McKenzie F, Capell H, Leiberman P, et al. Intermittent epoprostenol (prostacyclin) infusion in patients with Raynaud's syndrome: a double-blind controlled trial. Lancet 1983; 1: 313-315.
4. Ylitalo P, Kaukinen S, Seppale E, Nurmi A, Pessi T, Krais T, et al. Pharmacological effects of iloprost (ZK 36374), a stable prostacyclin analogue in man. Biomed Biochem Acta 1984; 43: 399-402.
5. Subcommittee for Scleroderma Criteria of the American Rheumatism Association. Arthritis Rheum 1980; 23: 581-590.
6. Tenland T. On laser Doppler flowmetry. Methods and microvascular applications. Linköping University Medical Dis. University of Linköping, 1982.
7. Kahaleh M. Endothelin an endothelial-dependent vasoconstrictor in scleroderma. Arthritis Rheum 1991; 34: 978-983.
8. Vorman H, Stehouer C, van Kamp G, van Schijndel R, Grone A, Thijs L. Plasma endothelin levels are increased during septic shock. Crit Care Med 1992; 20: 1097-1101.
9. McHugh N, Suka M, Watson H, Belcher G, Amadi A, Ring E, et al. Infusion of iloprost, a prostacyclin analogue for treatment of Raynaud's phenomenon in systemic sclerosis. Ann Rheum Dis 1988; 47: 43-47.
10. Zachariae H, Heickendorff L, Bjerring P, Halkier-Sørensen L, Søndergaard K. Plasma endothelin and the aminoterminal propeptide of type III procollagen (PIIINP) in systemic sclerosis. Acta Derm Venereol (Stockh) 1994; 74: 368-370.