Demonstration of a cross-talk between IL-2 and IL-S in phosphorylation of IL-2 and IL-5 receptor β chains

International Immunology

Volumn 8, Issue 6, 1996, Pages 951-960

  Ohbo, Kazuyuki ^a   Asao, Hironobu ^a   Kouro, Taku ^b   Nakamura, Masataka ^a   Takaki, Satoshi ^b   Kikuchi, Yuji ^b   Hirokawa, Katsuiku ^c   Tominaga, Akira ^d   Takatsu, Kiyoshi ^b   Sugamura, Kazuo ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c Tokyo Medical and Dental University ^*  (Japan)

^d KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

Cytokine receptors; IL 2; IL 5; Phosphorylation; Signal transduction

Indexed keywords

COMPLEMENTARY DNA; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 5; INTERLEUKIN 5 RECEPTOR; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIVISION; CELL LINE; INTERLEUKIN-2; INTERLEUKIN-5; JANUS KINASE 1; JANUS KINASE 2; JANUS KINASE 3; KINETICS; MICE; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-2; RECEPTORS, INTERLEUKIN-5; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0029933770     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.6.951     Document Type: Article

References (54)

1. Smith, K. A. 1988. Interleukin-2: inception, impact, and implications. Science 240:1169.
2. Taniguchi, T. 1995. Cytokine signaling through non-receptor protein tyrosine kinases. Science 268:251.
3. Nakamura, M., Asao, H., Takeshita, T. and Sugamura, K. 1993. Interleukin-2 receptor heterotrimer complex and intracellular signaling. Semin. Immunol. 5:309.
4. Asao, H., Takeshita, T., Ishii, N., Kumaki, S., Nakamura, M. and Sugamura, K. 1993. Reconstitution of functional interleukin 2 receptor complexes on fibroblastoid cells: Involvement of the cytoplasmic domain of the γ chain in two distinct signaling pathways. Proc. Natl Acad. Sci. USA 90:4127.
5. Takaki, S., Tominaga, A., Hitoshi, Y., Mita, S., Sonoda, E., Yamaguchi, N and Takatsu, K. 1990 Molecular cloning and expression of the murine interleukin-5 receptor. EMBO J. 9:4367.
6. Devos, R., Plaetinck, G., Heyden, J. V., Cornelis, S., Vandekerckhove, J., Fiers, W. and Tavernier, J. 1991. Molecular basis of a high affinity murine interleukin-5 receptor. EMBO J. 10:2133
7. Park, L. S., Martin, U., Sorensen, R., Luhr, S., Morrissey, P. J., Cosman, D. and Larsen, A. 1992. Cloning of the low-affinity murine granulocyte-macrophage colony-stimulating factor receptor and reconstitution of a high-affinity receptor complex. Proc. Natl Acad. Sci. USA 89:4295.
8. Hara, T. and Miyajima, A. 1992. Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3). EMBO J. 11:1875.
9. Murata, Y., Takaki, S., Migita, M., Kikuchi, Y., Tominaga, A. and Takatsu, K. 1992. Molecular cloning and expression of the human interleukin 5 receptor. J. Exp. Med. 175:341.
10. Kitamura, T., Sato, N., Arai, K. and Miyajima, A. 1991. Expression cloning of the human IL-3 receptor cDNA reveals a shared β subunit for the human IL-3 and GM-CSF receptors. Cell 66:1165.
11. Gearing, D. P., King, J. A., Gough, N. M. and Nicola, N. A. 1989. Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor. EMBO. J. 8:3667.
12. Tavernier, J., Devos, R., Cornells, S., Tuypens, T., Heyden, J. V., Fiers, W. and Plaetinck, G. 1991. A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF. Cell 66:1175.
13. Itoh, N., Yonehara, S., Schreurs, J., Gorman, D. M., Maruyama, K., Ishii, A., Yahara, I., Arai, K. and Miyajima, A. 1990. Cloning of an interleukin-3 receptor gene: a member of a distinct receptor gene family. Science 247:324.
14. Gorman, D. M., Itoh, N., Kitamura, T., Schreurs, J., Yonehara, S., Yahara, I., Arai, K. and Miyajima, A. 1990. Cloning and expression of a gene encoding an interleukin 3 receptor-like protein: identification of another member of the cytokine receptor gene family. Proc. Natl Acad. Sci. USA 87:5459.
15. Kitamura, T., Hayashida, K., Sakamaki, K., Yokota, T., Arai, K. and Miyajima, A. 1991. Reconstitution of functional receptors for human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that the protein encoded by the AIC2B cDNA is a subunit of the murine GM-CSF receptor. Proc. Natl Acad. Sci. USA 88:5082.
16. Hayashida, K., Kitamura, T., Gorman, D. M., Arai, K., Yokota, T. and Miyajima, A. 1990. Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor. Proc. Natl Acad. Sci. USA 87:9655.
17. Takaki, S., Mita, S., Kitamura, T., Yonehara, S., Yamaguchi, N., Tominaga, A., Miyajima, A. and Takatsu, A. 1991. Identification of the second subunit of the murine interleukin-5 receptor: interleukin-3 receptor-like protein, AIC2B is a component of the high affinity interleukin-5 receptor. EMBO J. 10:2833.
18. Takatsu, K., Takaki, S. and Hitoshi, Y. 1994. Interleukin-5 and its receptor system: implications in the immune system and inflammation. Adv. Immunol. 57:145.
19. Sato, S., Katagiri, T., Takaki, S., Kikuchi, Y. Hitoshi, Y., Yonehara, S., Tsukada, S., Kitamura, D., Watanabe, T., Witte, O. and Takatsu, K. 1994. IL-5 receptor-mediated tyrosine phosphorylation of SH2/ SH3-containing proteins and activation of bruton's tyrosine and janus 2 kinases. J. Exp. Med. 180:2101.
20. Tominaga, A., Mita, S., Kikuchi, Y., Hitoshi, Y., Takatsu, K., Nishikawa, S.-I. and Ogawa, M. 1989. Establishment of IL-5-dependent early B cell lines by long-term bone marrow cultures. Growth Factors 1:135.
21. Takaki, S., Murata, Y., Kitamura, T., Miyajima, A., Tominaga, A. and Takatsu, K. 1993. Reconstitution of the functional receptors for murine and human interleukin 5. J. Exp. Med. 177:1523.
22. Ihle, J. N., Witthuhn, B. A., Quelle, F. W., Yamamoto, K., Thierfelder, W. E., Kreider, B. and Silvennoinen, O. 1994. Signaling by the cytokine receptor superfamily: JAKs and STATs. Trends Biochem. Sci. 19:222.
23. Takeshita, T., Goto, Y., Tada, K., Nagata, K., Asao, H. and Sugamura, K. 1989. Monoclonal antibody defining a molecule possibly identical to the p75 subunit of interleukin 2 receptor. J. Exp. Med. 169:1323.
24. Suzuki, J., Takeshita, T., Ohbo, K., Asao, H., Tada, K. and Sugamura, K. 1989. IL-2 receptor subunit, p75: direct demonstration of its IL-2 binding ability by using a novel monoclonal antibody. Int. Immunol. 1:373.
25. Moreau, J. L., Nabholz, M., Diamanstein, T., Malek, T., Shevach, E. and Theze, J. 1987. Monoclonal antibodies identify three epitope clusters on the mouse p55 subunit of the interleukin-2 binding site. Eur J. Immunol. 17:927.
26. Yamaguchi, N., Hitoshi, Y., Mita, S., Hosoya, Y., Kikuchi, Y., Tominaga, A. and Takatsu, K. 1990. Characterization of the murine IL-5 receptors by using monoclonal anti-receptor antibody. Int. Immunol. 2:181.
27. Pan, C-I., Fukunaga, R., Yonehara, S. and Nagata, S. 1993. Unidirectional cross-phosphorylation between the granulocyte colony-stimulating factor and interleukin 3 receptor. J. Biol. Chem. 268:3443.
28. Yaegashi, N., Tada, K., Shiraishi H., Ishii, T., Nagata, K. and Sugamura, K. 1989. Characterization of monoclonal antibodies against human parvovirus B19. Microbiol. Immunol. 33:561.
29. Kumaki, S., Asao, H., Takeshita, T., Kurahayashi, Y., Nakamura, M., Beckers, T., Engels, J. W. and Sugamura, K. 1992. Cell type-specific phosphorylation of IL-2 receptor β chain in response to IL-2. FEBS Lett. 310:22.
30. tax Mol. Cell. Biol. 11:1313.
31. Hatakeyama, M., Mori, H., Doi, T. and Taniguchi, T. 1989. A restricted cytoplasmic region of IL-2 receptor β chain is essential for growth signal transduction but not for ligand binding and internalization. Cell 59:837.
32. Fujii, M. Sugamura, K., Nakai, S., Tanaka, Y., Tozawa, H. and Hinuma, Y. 1986. High- and low-affinity interleukin 2 receptors: Distinctive effects of monoclonal antibodies. J. Immunol. 137:1552.
33. Asao, H., Kumaki, S., Takeshita, T., Nakamura, M. and Sugamura, K. 1992. IL-2-dependent in vivo and in vitro tyrosine phosphorylation of IL-2 receptor γ chain. FEBS Letters 304:141.
34. Glenney, J. R., Jr, Zokas, L. and Kamps, M. P. 1988. Monoclonal antibodies to phosphotyrosine. J. Immunol. Methods 109:277.
35. Takaki, S., Kanazawa, H., Shiiba, M. and Takatsu, K. 1994. Critical cytoplasmic domain of the IL-5R α chain and its function in IL-5-mediated growth signal transduction. Mol. Cell. Biol. 14:7404.
36. Mills, G. B., Cheung, R. K., Grinstein, S. and Gelfand, E. W. 1985. Interleukin 2-induced lymphocyte proliferation is independent of increases in cytosolic-free calcium concentrations. J. Immunol. 134:2431.
37. Mills, G. B., Stewart, D. J., Mellors, A. and Gelfand, E. W. 1986. Interleukin 2 does not induce phosphatidylinositol hydrolysis in activated T cells. J. Immunol. 136:3019.
38. Mills, G. B., Girand, P., Grinstein, S. and Gelfand, E. W. 1988. Interleukin-2 induces proliferation of T lymphocyte mutants lacking protein kinase C. Cell 55:91.
39. Valge, V. E., Wong, J. G. P., Datlof, B. M., Sinskey, A. J. and Rao, A. 1988. Protein kinase C is required for responses to T cell receptor ligands but not to interleukin-2 in T cells. Cell 55:101.
40. Yamaguchi, N., Takahashi, T., Harada, N. and Takatsu, K. 1989. Mechanisms of the interleukin 5-induced differentiation of B cells. J. Biochem. (Tokyo) 106:837.
41. Asao, H., Takeshita, T., Nakamura, M., Nagata, K. and Sugamura, K. 1990 The evidence for the IL-2 receptor β chain processing from p70 to p75. Int. Immunol. 2:469.
42. Sugamura, K., Asao, H., Kondo, M., Tanaka, N., Nakamura, M. and Takeshita, T. 1995. The common γ chain for multiple cytokine receptors. Adv. Immunol. 59:225.
43. Tanaka, N., Asao, H., Ohbo, K., Ishii, N., Takeshita, T., Nakamura, M., Sasaki, H. and Sugamura, K. 1994 Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor β and γ chains Proc. Natl Acad. Sci. USA 91:7271.
44. Asao, H., Tanaka, N., Ishii, N., Higuchi, M., Takeshita, T., Nakamura, M., Shirasawa, T. and Sugamura, K. 1994 Interleukin 2-induced activation of JAK3: possible involvement in signal transduction for c-myc induction and cell proliferation. FEBS Lett. 351:201.
45. Johnston, J. A., Kawamura, M., Kirken, R. A., Chen, Y. Q., Blake, T. B., Shibuya, K., Ortaldo, J. R., McVicar, D. W. and O'Shea, J. J. 1994 Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2. Nature 370:151.
46. Witthuhn, B. A., Silvennoinen, O., Miura, O., Lai, K. S., Cwik, C., Liu, E. T. and Ihle, J. N. 1994 Involvement of the Jak-3 Janus kinase in signalling by interleukin 2 and 4 in lymphoid and myeloid cells. Nature 370:153.
47. Kirken, R. A., Rui, H., Malabarba, M. G. and Farrar, W. L. 1994 Identification of interleukin-2 receptor-associated tyrosine kinase p116 as novel leukocyte-specific Janus kinase. J. Biol. Chem. 269:19136.
48. Hatakeyama, M., Kono, T., Kobayashi, N., Kawahara, A., Levin, S. D., Perlmutter, R. M. and Taniguchi, T. 1991 Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association. Science 252:1523.
49. Torigoe, T., Saragovi, H. U. and Reed, J. C. 1992 Interleukin 2 regulates the activity of the lyn protein-tyrosine kinase in a B-cell line. Proc. Natl Acad. Sci. USA 89:2674.
50. Kobayashi, N., Kono, T., Hatakeyama, M., Minami, Y., Miyazaki, T, Perlmutter, R. M. and Taniguchi, T. 1993 Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transduction. Proc Natl Acad. Sci. USA 90:4201.
51. Minami, Y., Nakagawa, Y., Kawahara, A., Miyazaki, T., Sada, K., Yamamura, H. and Taniguchi, T. 1995 Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor, possible link with the c-myc induction pathway. Immunity 2:89.
52. Harada, N., Matsumoto, M., Takahashi, T., Koyama, N., Honjo, T., Tominaga, A. and Takatsu, K. 1987. T cell-replacing factor/ interleukin 5 induces not only B-cell growth and differentiation, but also increased expression of interleukin-2 receptors on activated B-cells. Immunol. Lett. 15:205.
53. Yoshimoto, T., Nakanishi, K., Matsui, K., Hirose, S., Hiroishi, K., Tanaka, K., Hada, T., Hamaoka, T. and Higashino, K. 1990. IL-5 up-regulates but IL-4 down-regulates IL-2R expression on a cloned B lymphoma line. J. Immunol. 144:183.
54. McFadden, H. J. and Koshland, M. E. 1991. Interleukin 2- and Interleukin 5-induced changes in the binding of regulatory factors to the J-chain gene promoter. Proc. Natl Acad. Sci. USA 88:11027.