메뉴 건너뛰기




Volumn 64, Issue 6, 1996, Pages 2144-2150

Synthesis of hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits: Potential for use in a broad-spectrum vaccine

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA TOXIN B SUBUNIT; CHOLERA VACCINE; ESCHERICHIA COLI ENTEROTOXIN; ESCHERICHIA COLI VACCINE; HYBRID PROTEIN; MUTANT PROTEIN; RECOMBINANT VACCINE;

EID: 0029933633     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.6.2144-2150.1996     Document Type: Article
Times cited : (52)

References (33)
  • 1
    • 0027182394 scopus 로고
    • Intestinal antibody response after oral immunisation with a prototype B subunit-CFA enterotoxigenic Escherichia coli vaccine
    • Åhren, C., C. Wennerås, J. Holmgren and A.-M. Svennerholm. 1993. Intestinal antibody response after oral immunisation with a prototype B subunit-CFA enterotoxigenic Escherichia coli vaccine. Vaccine 11:929-935.
    • (1993) Vaccine , vol.11 , pp. 929-935
    • Åhren, C.1    Wennerås, C.2    Holmgren, J.3    Svennerholm, A.-M.4
  • 2
    • 0001845266 scopus 로고
    • The epidemiology of cholera and enterotoxigenic E. coli diarrheal diseases
    • J. Holmgren, A. Lindberg, and R. Mölby (ed.), Development of vaccines and drugs against diarrhea Studentlitteratur, Lund, Sweden
    • Black, R. E. 1986. The epidemiology of cholera and enterotoxigenic E. coli diarrheal diseases, p. 23-32. In J. Holmgren, A. Lindberg, and R. Mölby (ed.), Development of vaccines and drugs against diarrhea. Proceedings of the 11th Nobel Conference. Studentlitteratur, Lund, Sweden.
    • (1986) Proceedings of the 11th Nobel Conference , pp. 23-32
    • Black, R.E.1
  • 5
    • 0028935644 scopus 로고
    • Identification of errors among the database sequence entries and comparison of correct amino acid sequences for the heat-labile enterotoxin of Escherichia coli and Vibrio cholerae
    • Domenighini, M., M. Pizza, M. G. Jobling, R. K. Holmes, and R. Rappuoli. 1995. Identification of errors among the database sequence entries and comparison of correct amino acid sequences for the heat-labile enterotoxin of Escherichia coli and Vibrio cholerae. Mol. Microbiol. 15:1165-1167.
    • (1995) Mol. Microbiol. , vol.15 , pp. 1165-1167
    • Domenighini, M.1    Pizza, M.2    Jobling, M.G.3    Holmes, R.K.4    Rappuoli, R.5
  • 6
    • 0016289509 scopus 로고
    • Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: A rapid, sensitive in vitro assay for enterotoxins of Vibrio choleme and Escherichia coli
    • Guerrant, R. L., L. L. Brunton, R. C. Schnaitman, L. I. Rebhun, and A. G. Gliman. 1974. Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for enterotoxins of Vibrio choleme and Escherichia coli. Infect. Immun. 10:320-327.
    • (1974) Infect. Immun. , vol.10 , pp. 320-327
    • Guerrant, R.L.1    Brunton, L.L.2    Schnaitman, R.C.3    Rebhun, L.I.4    Gliman, A.G.5
  • 7
    • 0019448149 scopus 로고
    • Actions of cholera toxin and the prevention and treatment of cholera
    • Holmgren, J. 1981. Actions of cholera toxin and the prevention and treatment of cholera. Nature (London) 292:413-417.
    • (1981) Nature (London) , vol.292 , pp. 413-417
    • Holmgren, J.1
  • 8
    • 9344223473 scopus 로고    scopus 로고
    • Unpublished data
    • 7a. Holmgren, J., et al. Unpublished data.
    • Holmgren, J.1
  • 9
    • 0019935016 scopus 로고
    • Rabbit intestinal glycoprotein receptor for Escherichia coli heat-labile enterotoxin lacking affinity for cholera toxin
    • Holmgren, J., P. Fredman, M. Lindblad, A.-M. Svennerholm, and L. Svennerholm. 1982. Rabbit intestinal glycoprotein receptor for Escherichia coli heat-labile enterotoxin lacking affinity for cholera toxin. Infect. Immun. 38: 424-433.
    • (1982) Infect. Immun. , vol.38 , pp. 424-433
    • Holmgren, J.1    Fredman, P.2    Lindblad, M.3    Svennerholm, A.-M.4    Svennerholm, L.5
  • 12
    • 0021139224 scopus 로고
    • Recombinant nontoxigenic Vibrio cholerae strains as attenuated cholera vaccine candidates
    • Kaper, J. B., H. Lockman, M. M. Baldini, and M. M. Levine. 1984. Recombinant nontoxigenic Vibrio cholerae strains as attenuated cholera vaccine candidates. Nature (London) 308:655-658.
    • (1984) Nature (London) , vol.308 , pp. 655-658
    • Kaper, J.B.1    Lockman, H.2    Baldini, M.M.3    Levine, M.M.4
  • 14
    • 0027420419 scopus 로고
    • Overexpression of recombinant cholera toxin B subunit for use in oral vaccines
    • Lebens, M., S. Johansson, J. Osek, M. Lindblad, and J. Holmgren. 1993. Overexpression of recombinant cholera toxin B subunit for use in oral vaccines. Bio/Technology 11:1574-1578.
    • (1993) Bio/Technology , vol.11 , pp. 1574-1578
    • Lebens, M.1    Johansson, S.2    Osek, J.3    Lindblad, M.4    Holmgren, J.5
  • 15
    • 0021998271 scopus 로고
    • Nucleotide sequence comparison between heat-labile toxin B subunit cistrons from Escherichia coli of human and porcine origin
    • Leong, J., A. C. Vinal, and W. S. Dallas. 1985. Nucleotide sequence comparison between heat-labile toxin B subunit cistrons from Escherichia coli of human and porcine origin. Infect. Immun. 48:73-78.
    • (1985) Infect. Immun. , vol.48 , pp. 73-78
    • Leong, J.1    Vinal, A.C.2    Dallas, W.S.3
  • 18
    • 0025825965 scopus 로고
    • Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-γ production and invokes immunological memory
    • Quiding, M., I. Nordström, A. Kilander, G. Andersson, L.-Å. Hanson, J. Holmgren, and C. Czerkinsky. 1991. Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-γ production and invokes immunological memory. J. Clin. Invest. 88:143-148.
    • (1991) J. Clin. Invest. , vol.88 , pp. 143-148
    • Quiding, M.1    Nordström, I.2    Kilander, A.3    Andersson, G.4    Hanson, L.-Å.5    Holmgren, J.6    Czerkinsky, C.7
  • 20
    • 0040172243 scopus 로고
    • Recombinant system for overexpression of cholera toxin B subunit in Vibrio cholerae as a basis for vaccine development
    • Sanchez, J., and J. Holmgren. 1989. Recombinant system for overexpression of cholera toxin B subunit in Vibrio cholerae as a basis for vaccine development. Proc. Natl. Acad. Sci. USA 86:481-485.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 481-485
    • Sanchez, J.1    Holmgren, J.2
  • 21
    • 0023631374 scopus 로고
    • Alterations at the carboxyl terminus change assembly and secretion properties of the B subunit of Escherichia coli heat-labile enterotoxin
    • Sandkvist, M., T. Hirst, and M. Bagdasarian. 1987. Alterations at the carboxyl terminus change assembly and secretion properties of the B subunit of Escherichia coli heat-labile enterotoxin. J. Bacteriol. 169:4570-4576.
    • (1987) J. Bacteriol. , vol.169 , pp. 4570-4576
    • Sandkvist, M.1    Hirst, T.2    Bagdasarian, M.3
  • 22
    • 0001359135 scopus 로고
    • Hybrid hepatitis B virus core/ pre-S particles expressed in attenuated Salmonellae for oral immunisation
    • F. Brown, R. M. Chanock, H. S. Ginsberg, and R. A. Lerner (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Schödel, F., D. R. Milich, and H. Will. 1991. Hybrid hepatitis B virus core/ pre-S particles expressed in attenuated Salmonellae for oral immunisation, p. 319-325. In F. Brown, R. M. Chanock, H. S. Ginsberg, and R. A. Lerner (ed.), Vaccines 91. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (1991) Vaccines 91 , pp. 319-325
    • Schödel, F.1    Milich, D.R.2    Will, H.3
  • 23
  • 25
    • 0026458260 scopus 로고
    • Structure and function of cholera toxin and the related heat-labile enterotoxin of Escherichia coli
    • Spangler, B. D. 1992. Structure and function of cholera toxin and the related heat-labile enterotoxin of Escherichia coli. Microbiol. Rev. 56:622-647.
    • (1992) Microbiol. Rev. , vol.56 , pp. 622-647
    • Spangler, B.D.1
  • 26
    • 0011053586 scopus 로고
    • Development of an oral vaccine against enterotoxigenic E. coli diarrhea
    • T. Wadström, H. Mekele, A.-M. Svennerholm, and H. Wolf-Watz (ed.), Plenum Press, London
    • Svennerholm, A.-M., C. Åhren, C. Wennerås, and J. Holmgren. 1991. Development of an oral vaccine against enterotoxigenic E. coli diarrhea, p. 287-294. In T. Wadström, H. Mekele, A.-M. Svennerholm, and H. Wolf-Watz (ed.), Molecular pathogenesis of gastrointestinal infections. Plenum Press, London.
    • (1991) Molecular Pathogenesis of Gastrointestinal Infections , pp. 287-294
    • Svennerholm, A.-M.1    Åhren, C.2    Wennerås, C.3    Holmgren, J.4
  • 27
    • 0021670283 scopus 로고
    • Local and systemic antibody responses and immunological memory in humans after immunization with cholera toxin B subunit by different routes
    • Svennerholm, A.-M., L. Gothefors, D. A. Sack, P. K. Bardhan, and J. Holmgren. 1984. Local and systemic antibody responses and immunological memory in humans after immunization with cholera toxin B subunit by different routes. Bull. W.H.O. 62:909-918.
    • (1984) Bull. W.H.O. , vol.62 , pp. 909-918
    • Svennerholm, A.-M.1    Gothefors, L.2    Sack, D.A.3    Bardhan, P.K.4    Holmgren, J.5
  • 28
    • 0017236508 scopus 로고
    • Synergistic protective effect in rabbits of immunization with Vibrio cholerae lipopolysaccharide and toxin/ toxoid
    • Svennerholm, A.-M., and J. Holmgren. 1976. Synergistic protective effect in rabbits of immunization with Vibrio cholerae lipopolysaccharide and toxin/ toxoid. Infect. immun. 13:735-740.
    • (1976) Infect. Immun. , vol.13 , pp. 735-740
    • Svennerholm, A.-M.1    Holmgren, J.2
  • 29
    • 0018221811 scopus 로고
    • Identification of Escherichia coli heat-labile enterotoxin by means of a ganglioside immunosorbent assay (GM1 ELISA) procedure
    • Svennerholm, A.-M., and J. Holmgren. 1978. Identification of Escherichia coli heat-labile enterotoxin by means of a ganglioside immunosorbent assay (GM1 ELISA) procedure. Curr. Microbiol. 1:19-23.
    • (1978) Curr. Microbiol. , vol.1 , pp. 19-23
    • Svennerholm, A.-M.1    Holmgren, J.2
  • 30
    • 0020655530 scopus 로고
    • Serologic differentiation between antitoxic responses to infection with Vibrio cholerae and enterotoxin-producing Escherichia coli
    • Svennerholm, A.-M., J. Holmgren, R. Black, M. Levine, and M. M. Merson. 1983. Serologic differentiation between antitoxic responses to infection with Vibrio cholerae and enterotoxin-producing Escherichia coli. J. Infect. Dis. 147: 514-522.
    • (1983) J. Infect. Dis. , vol.147 , pp. 514-522
    • Svennerholm, A.-M.1    Holmgren, J.2    Black, R.3    Levine, M.4    Merson, M.M.5
  • 31
    • 0021256044 scopus 로고
    • Mucosal antitoxic and antibacterial immunity after cholera disease and after immunization with a combined B subunitwhole cell vaccine
    • Svennerholm, A.-M., M. Jertborn, L. Gothefors, A. M. M. M. Karim, D. A. Sack, and J. Holmgren. 1984. Mucosal antitoxic and antibacterial immunity after cholera disease and after immunization with a combined B subunitwhole cell vaccine. J. Infect. Dis. 149:884-893.
    • (1984) J. Infect. Dis. , vol.149 , pp. 884-893
    • Svennerholm, A.-M.1    Jertborn, M.2    Gothefors, L.3    Karim, A.M.M.M.4    Sack, D.A.5    Holmgren, J.6
  • 32
    • 0020042470 scopus 로고
    • Intestinal antibody responses after immunization with cholera toxin B subunit
    • Svennerholm, A.-M., D. A. Sack, J. Holmgren, and P. K. Bardhan. 1982. Intestinal antibody responses after immunization with cholera toxin B subunit. Lancet i:305-308.
    • (1982) Lancet , vol.1 , pp. 305-308
    • Svennerholm, A.-M.1    Sack, D.A.2    Holmgren, J.3    Bardhan, P.K.4
  • 33
    • 0022448625 scopus 로고
    • Monoclonal antibodies to Escherichia coli heat-labile enterotoxins: Neutralising activity and differentiation of human and porcine LTs and cholera toxin
    • Svennerholm, A.-M., M. Wickström, M. Lindblad, and J. Holmgren. 1986. Monoclonal antibodies to Escherichia coli heat-labile enterotoxins: neutralising activity and differentiation of human and porcine LTs and cholera toxin. Med. Biol. 64:23-30.
    • (1986) Med. Biol. , vol.64 , pp. 23-30
    • Svennerholm, A.-M.1    Wickström, M.2    Lindblad, M.3    Holmgren, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.