메뉴 건너뛰기




Volumn 270, Issue 2 39-2, 1996, Pages

Substrate and inhibitor specificities of the monocarboxylate transporters of single rat heart cells

Author keywords

2',7' bis(carboxyethyl) 5(6) carboxyfluorescein; fluorescence; intracellular pH; ketone bodies; lactate; plasma membrane; pyruvate

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 4,4' DINITRO 2,2' STILBENEDISULFONIC ACID; 5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; ALPHA CYANO 4 HYDROXYCINNAMIC ACID; CARBOXYLIC ACID DERIVATIVE; CARRIER PROTEIN; ISOBUTYLMETHYLXANTHINE;

EID: 0029933573     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.270.2.h476     Document Type: Article
Times cited : (64)

References (21)
  • 1
    • 0014376470 scopus 로고
    • Turnover rates of ketone bodies in normal, starved and alloxan-diabetic rats
    • Bates, M. W., H. A. Krebs, and D. H. Williamson. Turnover rates of ketone bodies in normal, starved and alloxan-diabetic rats. Biochem. J. 110: 655-661, 1968.
    • (1968) Biochem. J. , vol.110 , pp. 655-661
    • Bates, M.W.1    Krebs, H.A.2    Williamson, D.H.3
  • 2
    • 0028605480 scopus 로고
    • The kinetics, substrate and inhibitor specificity of the lactate transporter of Ehrlich-Lettré tumour cells studies using the intracellular pH indicator BCECF
    • Carpenter, L., andA. P. Halestrap. The kinetics, substrate and inhibitor specificity of the lactate transporter of Ehrlich-Lettré tumour cells studies using the intracellular pH indicator BCECF. Biochem. J. 304: 751-760, 1994.
    • (1994) Biochem. J. , vol.304 , pp. 751-760
    • Carpenter, L.1    Halestrap, A.P.2
  • 3
    • 0020825770 scopus 로고
    • Influence of organic acids on intracellular pH
    • Cell Physiol. 14
    • DeHemptinne, A., R. Marrannes, and B. Vanheel. Influence of organic acids on intracellular pH. Am. J. Physiol. 245 (Cell Physiol. 14): C178-C183 1983.
    • (1983) Am. J. Physiol. , vol.245
    • DeHemptinne, A.1    Marrannes, R.2    Vanheel, B.3
  • 4
    • 0022413758 scopus 로고
    • Kinetic analysis of monocarboxylate uptake into perfused rat hearts
    • Dennis, S., M. C. Kohn, G. J. Anderson, and D. Garfinkel. Kinetic analysis of monocarboxylate uptake into perfused rat hearts. J Mol. Cell. Cardiol. 17: 987-995, 1985.
    • (1985) J Mol. Cell. Cardiol. , vol.17 , pp. 987-995
    • Dennis, S.1    Kohn, M.C.2    Anderson, G.J.3    Garfinkel, D.4
  • 5
    • 0020063756 scopus 로고
    • The external anion binding site of the human erythrocyte anion transporter: DNDS binding and competition with chloride
    • Fröhlich, O. The external anion binding site of the human erythrocyte anion transporter: DNDS binding and competition with chloride. J. Membr. Biol. 65: 111-123, 1982.
    • (1982) J. Membr. Biol. , vol.65 , pp. 111-123
    • Fröhlich, O.1
  • 6
    • 0028909335 scopus 로고
    • CDNA cloning of MCT-2, a second monocarboxylate transporter expressed in different cells than MCT-1
    • Garcia, C. K., M. S. Brown, R. K. Pathak, and J. L. Goldstein. cDNA cloning of MCT-2, a second monocarboxylate transporter expressed in different cells than MCT-1. J. Biol. Chem. 270, 1843-1849, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1843-1849
    • Garcia, C.K.1    Brown, M.S.2    Pathak, R.K.3    Goldstein, J.L.4
  • 7
    • 0028294023 scopus 로고
    • Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates-implications for the Cori cycle
    • Garcia, C. K, J. L. Goldstein, R. K. Pathak, R. G. W. Anderson, and M. S. Brown. Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates-implications for the Cori cycle. Cell 76: 865-873, 1994.
    • (1994) Cell , vol.76 , pp. 865-873
    • Garcia, C.K.1    Goldstein, J.L.2    Pathak, R.K.3    Anderson, R.G.W.4    Brown, M.S.5
  • 8
    • 0021979579 scopus 로고
    • Characteristics of lactate transfer in isolated cardiac myocytes
    • Kammermeier, H., B. Wein, and W. Graf. Characteristics of lactate transfer in isolated cardiac myocytes. Basic Res. Cardiol. 80, Suppl. 1: 57-60, 1985.
    • (1985) Basic Res. Cardiol. , vol.80 , Issue.1 SUPPL. , pp. 57-60
    • Kammermeier, H.1    Wein, B.2    Graf, W.3
  • 9
    • 0026463075 scopus 로고
    • cDNA cloning of MEV, a mutant protein that facilitates cellular uptake of mevalonate, and identification of a point mutation responsible for its gain in function
    • Kim, C. M., J. L. Goldstein, and M. S. Brown. cDNA cloning of MEV, a mutant protein that facilitates cellular uptake of mevalonate, and identification of a point mutation responsible for its gain in function. J Biol. Chem. 267: 23113-23121, 1992.
    • (1992) J Biol. Chem. , vol.267 , pp. 23113-23121
    • Kim, C.M.1    Goldstein, J.L.2    Brown, M.S.3
  • 10
    • 0022371325 scopus 로고
    • Evidence for a lactate transport system in the sarcolemmal membrane of the perfused rabbit heart: Kinetics of unidirectional influx, carrier specificity and effects of glucagon
    • Mann, G. E., B. V. Zlokovic, and D. L. Yudilevich. Evidence for a lactate transport system in the sarcolemmal membrane of the perfused rabbit heart: kinetics of unidirectional influx, carrier specificity and effects of glucagon. Biochim. Biophys. Acta 19: 241-248, 1985.
    • (1985) Biochim. Biophys. Acta , vol.19 , pp. 241-248
    • Mann, G.E.1    Zlokovic, B.V.2    Yudilevich, D.L.3
  • 11
    • 0025286737 scopus 로고
    • Substrate and inhibitor specificity of monocarboxylate transport into heart cells and erythrocytes - Further evidence for the existence of 2 distinct carriers
    • Poole, R. C., S. L. Cranmer, A. P. Halestrap, and A. J. Levi. Substrate and inhibitor specificity of monocarboxylate transport into heart cells and erythrocytes - further evidence for the existence of 2 distinct carriers. Biochem. J. 269: 827-829, 1990.
    • (1990) Biochem. J. , vol.269 , pp. 827-829
    • Poole, R.C.1    Cranmer, S.L.2    Halestrap, A.P.3    Levi, A.J.4
  • 12
    • 0025775032 scopus 로고
    • Reversible and irreversible inhibition, by stilbenedisulphonates, of lactate transport into rat erythrocytes-identification of some new high-affinity inhibitors
    • Poole, R. C., andA. P. Halestrap. Reversible and irreversible inhibition, by stilbenedisulphonates, of lactate transport into rat erythrocytes-identification of some new high-affinity inhibitors. Biochem. J. 275: 307-312, 1991.
    • (1991) Biochem. J. , vol.275 , pp. 307-312
    • Poole, R.C.1    Halestrap, A.P.2
  • 13
    • 0027418622 scopus 로고
    • Transport of lactate and other monocarboxylates across mammalian plasma membranes
    • Cell Physiol. 33
    • Poole, R. C., andA. P. Halestrap. Transport of lactate and other monocarboxylates across mammalian plasma membranes. Am. J. Physiol. 264 (Cell Physiol. 33): C761-C782, 1993.
    • (1993) Am. J. Physiol. , vol.264
    • Poole, R.C.1    Halestrap, A.P.2
  • 14
    • 0028072697 scopus 로고
    • N-terminal protein sequence analysis of the rabbit erythrocyte lactate transporter suggests identity with the cloned monocarboxylate transport protein MCT-1
    • Poole, R. C., andA. P. Halestrap. N-terminal protein sequence analysis of the rabbit erythrocyte lactate transporter suggests identity with the cloned monocarboxylate transport protein MCT-1. Biochem. J. 303: 755-759, 1994.
    • (1994) Biochem. J. , vol.303 , pp. 755-759
    • Poole, R.C.1    Halestrap, A.P.2
  • 15
    • 0024827005 scopus 로고
    • The kinetics of transport of lactate and pyruvate into isolated cardiac myocytes from guinea pig-kinetic evidence for the presence of a carrier distinct from that in erythrocytes and hepatocytes
    • Poole, R. C., A. P. Halestrap, S. J. Price, and A. J. Levi. The kinetics of transport of lactate and pyruvate into isolated cardiac myocytes from guinea pig-kinetic evidence for the presence of a carrier distinct from that in erythrocytes and hepatocytes. Biochem. J. 264: 409-418, 1989.
    • (1989) Biochem. J. , vol.264 , pp. 409-418
    • Poole, R.C.1    Halestrap, A.P.2    Price, S.J.3    Levi, A.J.4
  • 17
    • 0018862072 scopus 로고
    • Utilization of energy-providing substrates in the isolated working rat heart
    • Taegtmeyer, H., R. Hems, and H. A. Krebs. Utilization of energy-providing substrates in the isolated working rat heart. Biochem. J. 186: 701-711, 1980.
    • (1980) Biochem. J. , vol.186 , pp. 701-711
    • Taegtmeyer, H.1    Hems, R.2    Krebs, H.A.3
  • 18
    • 0024419420 scopus 로고
    • Functional characteristics of the cardiac sarcolemmal monocarboxylate transporter
    • Trosper, T. L., andK. D. Philipson. Functional characteristics of the cardiac sarcolemmal monocarboxylate transporter J. Membr. Biol. 112: 15-23, 1989.
    • (1989) J. Membr. Biol. , vol.112 , pp. 15-23
    • Trosper, T.L.1    Philipson, K.D.2
  • 19
    • 0023176356 scopus 로고
    • Lactate transport by cardiac sarcolemmal membrane vesicles
    • Cell Physiol. 21
    • Trosper, T. L., andK. D. Philipson. Lactate transport by cardiac sarcolemmal membrane vesicles. Am. J. Physiol. 252 (Cell Physiol. 21): C483-C489, 1987.
    • (1987) Am. J. Physiol. , vol.252
    • Trosper, T.L.1    Philipson, K.D.2
  • 20
    • 0028087225 scopus 로고
    • Kinetics of the sarcolemmal lactate carrier in single heart cells using BCECF to measure internal pH
    • Heart Circ. Physiol. 36
    • Wang, X., A. J. Levi, and A. P. Halestrap. Kinetics of the sarcolemmal lactate carrier in single heart cells using BCECF to measure internal pH. Am. J. Physiol. 267 (Heart Circ. Physiol. 36: H1759-H1769, 1994.
    • (1994) Am. J. Physiol. , vol.267
    • Wang, X.1    Levi, A.J.2    Halestrap, A.P.3
  • 21
    • 0027462108 scopus 로고
    • Characterization of the inhibition by stilbene disulphonates and phloretin of lactate and pyruvate transport into rat and guinea pig cardiac myocytes suggests the presence of 2 kinetically distinct carriers in heart cells
    • Wang, X., R. C. Poole, A. P. Halestrap, and A. J. Levi. Characterization of the inhibition by stilbene disulphonates and phloretin of lactate and pyruvate transport into rat and guinea pig cardiac myocytes suggests the presence of 2 kinetically distinct carriers in heart cells Biochem. J. 290: 249-258, 1993.
    • (1993) Biochem. J. , vol.290 , pp. 249-258
    • Wang, X.1    Poole, R.C.2    Halestrap, A.P.3    Levi, A.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.