Synthesis and in vitro cytotoxicity of (RS)-20-desethyl-20-substituted camptothecin analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 7, 1996, Pages 849-852

  Jew, Sang Sup ^a   Kim, Myoung Goo ^a   Kim, Hee Jin ^a   Roh, Eun Young ^a   Cho, Youn Sang ^a   Kim, Joon Kyum ^b   Cha, Kyung Hoe ^b   Lee, Kang Keun ^b   Han, Hyun Jung ^b   Lee, Heesoon ^c  

^a Seoul National University   (South Korea)

^b Chong Kun Dang Research Institute   (South Korea)

^c Chungbuk National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CAMPTOTHECIN DERIVATIVE;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HUMAN; HUMAN CELL; TUMOR CELL;

EID: 0029933352     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00132-1     Document Type: Article

References (13)

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11. 50, μM).
12. All new compounds gave satisfactory spectroscopic data consistent with the proposed structures.
13. Jew, S. S.; Kim, H. J.; Kim, M. G.; Roh, E. Y.; Cho, Y. S.; Kim, J. K.; Cha, K. H.; Lee, K. K.; Han, H. J.; Choi, J. Y.; Lee, H. Bioorg. Med. Chem. Lett. submitted.