Transformation of immortalized woodchuck hepatic cell lines with the c-Ha-ras proto-oncogene

Carcinogenesis

Volumn 17, Issue 4, 1996, Pages 631-636

  Jacob, James R ^a   Tennant, Bud C ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN; VIRUS T ANTIGEN;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRUCTURE; CELL TRANSFORMATION; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; GENETIC TRANSFECTION; GROWTH RATE; IMMUNOBLOTTING; LATENT PERIOD; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; NORTHERN BLOTTING; ONCOGENE H RAS; PHENOTYPE; PRIORITY JOURNAL; SIMIAN VIRUS 40; WOODCHUCK;

3T3 CELLS; ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CELL LINE, TRANSFORMED; GENES, RAS; IMMUNOBLOTTING; LIVER; MARMOTA; MICE; MICE, SCID;

EID: 0029933186     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.4.631     Document Type: Article

References (28)

1. Popper,H., Shafritz,D.A. and Hoofnagle,J.H. (1987) Relation of the hepatitis B virus camer state to hepatocellular carcinoma. Hepatology, 14, 198-199.
2. Popper,H., Roth,R., Purcell,R.H., Tennant,B.C and Gerin,J.L. (1987) Hepatocarcinogenicity of the woodchuck hepatitis virus. Proc. Natl Acad. Sci USA. 84, 866-870.
3. Woodworth,C.D. and Isom,H.C. (1987) Regulation of albumin gene expression in a series of rat hepatocyte cell lines immortalized by SV40 and maintained in chemically defined medium. Mol. Cell. Biol., 7, 3740-3748.
4. Lanford,R.E., Carey,K.D., Estlack,L.E., Smith,G.C. and Hay,R.V. (1989) Analysis of plasma protein and lipoprotein synthesis in long-term primary cultures of baboon hepatocytes maintained in serum-free medium. In Vitro Cell Dev. Biol., 25, 174-182.
5. Jacob,J.R., Estlack,L.E. and Lanford,R.E. (1992) Immortalization of chimpanzee hepatocytes with an amphoteric retrovirus encoding simian virus 40 T antigen. Exp. Cell Res., 200, 205-210.
6. Isom,H.C, Woodworth,C.D., Meng,Y. Kreider,J., Miller,T. and Mengel,L. (1992) Introduction of the ras oncogene transforms a simian virus 40-immortalized hepatocyte cell line without loss of expression of albumin and other liver-specific genes Cancer Res., 52, 940-948
7. Fang,X.-J., Flowers,M., Keating,A., Cameron,R. and Sherman,M. (1992) Ras transformation of simian virus 40-immortalized rat hepatocytes: an in vitro model of hepatocarcinogenesis. Cancer Res., 51, 173-180.
8. Hohne,M., Schaefer,S., Seifer,M., Feitelson,M.A., Paul,D. and Gerlich,W.H. (1990) Malignant transformation of immortalized transgenic hepatocytes after transfection with hepatitis B virus DNA. EMBO J., 9, 1137-1145.
9. Schödel,F., Sprengel,R., Weimer,T., Fernholz,D., Schneider,R. and Will,H. (1989) Animal Hepatitis B Viruses. In Klein,G. (ed.). Advances in Viral Oncology. Raven Press, New York. pp. 73-102.
10. Liu,R.H., Jacob,J.R., Tennant,B.C. and Hotchkiss,J.H. (1992) Nitrate and nitrosamine synthesis by hepatocytes isolated from normal woodchucks (Marmota monax) and woodchucks chronically infected with woodchuck hepatitis virus. Cancer Res., 52, 4139-4143.
11. Liu,R.H., Baldwin,B., Tennant,B.C. and Hotchkiss,J.H (1991) Elevated formation of nitrate and N-nitrosodimethylamine in woodchucks (Marmota monax) associated with chronic woodchuck hepatitis virus infection. Cancer Res., 51, 3925-3929.
12. Jacob,J.R., Liu,R.H., Ronekar,C., Noronha,F., Hotchkiss,J.H. and Tennant,B.C. (1994) Characterization and immortalization of woodchuck hepatocytes isolated from normal and hepadnavirus-infected woodchucks (Marmota monax). Exp. Cell Res., 212, 42-48.
13. Liu,R.H., Jacob,J.R., Hotchkiss,J.H and Tennant,B.C (1993) Synthesis of nitric oxide and nitrosamine by immortalized woodchuck hepatocytes. Carcinogenesis, 14, 1609-1613.
14. Felgner,P.L., Gadek,T.R., Holm,M., Roman,R., Chan,H.W., Weinz,M., Northrup,J,P., Ringold,G.M. and Danielson,M (1987) Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl Acad. Sci. USA, 84, 7413-7417.
15. MacPhearson,I. and Montagnier,L. (1964) Agar suspension culture for the selective assay of cells transformed by polyoma virus. Virology, 23, 291-294.
16. Laemmli,U. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227, 680-695.
17. Towbin,H., Staehlin,T. and Gordon,J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad. Sci. USA, 76, 4350-4354.
18. Vachereau,A. (1989) Luminescent immunodetection of Western-blotted proteins from coomassie-stained polyacrylamide gel. Anal. Biochem., 179, 206-208.
19. Sambrook,J., Fritsch,E.F. and Maniatis,T. (1989) In Nolan,C.(ed.), Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Habor, NY.
20. Chomocyski,K. and Sacchi,N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
21. Bosmu,M.J and Carroll,A.M. (1991) The SCID mouse mutant definition, characterization, and potential uses. Annu. Rev. Immunol, 9, 323-350.
22. Ruley,H.E. (1990) Transforming collaborations between ras and nuclear oncogenes. Cancer Cells, 2, 258-268.
23. Toshkov,L. Hacker,H.J., Roggendorf,M. and Bannasch,P. (1990) Phenotypic patterns of preneoplastic and neopiastic hepatic lesions in woodchucks infected with woodchuck hepatitis virus. J. Cancer Res. Clin. Oncology, 116, 581-590.
24. Abe,K., Kurata,T., Shikata,T., and Tennani,B.C. (1988) Enzyme altered liver cell foci in woodchucks infected with woodchuck hepatilis virus. Jpn J. Cancer Res., 79, 466-472.
25. Fourel,G., Trepo,C., Bougueleret,L., Henglein,B., Ponzetto,A., Tiollais,P. and Buendia,M.-A. (1990) Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumours. Nature. 347, 294-298.
26. Hansen,L.J., Tennant,B.C. Seeger,C. and Ganem,D. (1993) Differential activation of myr gene family members in hepatic carcinogenesis by closely related hepatitis B viruses. Mol. Cell. Biol., 13, 659-667.
27. Seeger,C., Baldwin,B., Hombuckle,W.E., Yeager,A.E., Tennant,B.C., Cote,P., Ferrell,L., Ganem,D. and Varmus,H.E. (1991) Woodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host. J. Virol., 65, 1673-1679.
28. Transy,C., Fourel,G., Robinson,W.S., Tiollias,P., Marion,P.L. and Buendia,M.-A. (1992) Frequent amplification of c-myc in ground squirrel liver tumors associated with past or ongoing infection with a hepadnavirus. Proc. Natl Acad. Sci. USA, 89, 3874-3878.