Effects of Endothelin-1 on Hepatic Blood Flow

HPB Surgery

Volumn 9, Issue 3, 1996, Pages 153-159

  Unneberg, Kjetil ^a   Mjaaland, Marianne ^a   Revhaug, Arthur ^a   Helseth, Elin ^a  

^a University Hospital of Tromosø   (Norway)

Author keywords

Endothelin 1 hepaticbloodflow hepatic artery flow portal vein flow portal vein pressure

Indexed keywords

ENDOTHELIN 1;

ANIMAL EXPERIMENT; ARTICLE; ASCITES; CONTROLLED STUDY; DRUG CLEARANCE; DRUG EFFECT; INTRAVENOUS DRUG ADMINISTRATION; LIVER BLOOD FLOW; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; NONHUMAN; PORTAL VEIN BLOOD FLOW; PORTAL VEIN BLOOD PRESSURE; PRIORITY JOURNAL; SWINE; VEIN RESISTANCE;

ANIMALS; ENDOTHELINS; LIVER CIRCULATION; SWINE; VASCULAR RESISTANCE;

EID: 0029933142     PISSN: 08948569     EISSN: 16078462     Source Type: Journal    
DOI: 10.1155/1996/69047     Document Type: Article

References (23)

1. Yanagisawa, M., Kurihara, H., Kimura, S., Tomobe, Y., Kobayashi, M., Mitsui, Y., Yzaki, Y., Goto, K., and Masaki, T (1988) A noval potent vasoconstrictor peptide produced by vascular endothelial cells. Nature, 332 411–415.
2. Lüscher, T.F., Boulanger, C.M., Dohi, Y. and Yang, Z. (1992) Endothelium-Derived Contracting Factors. Hypertension, 19 117–130.
3. Brain, S.D., Crossman, D.C., Buckley, T.L. and Williams, T.J. (1989) Endothelin-1: Demonstration of potent effects on the microcirculation of humans and other species, Journal of Cardiovascular Pharmacology, 13 (suppl 5) 147–149.
4. Clarke, J.G., Larkin, S.W., Benjamin, N., Keogh, B.E. and Chester, A. (1989) Endothelin-1 is a potent long-lasting vasoconstrictor in dog peripheral vasculature in vivo. Journal of Cardiovascular Pharmacology, 13 (suppl 5) 211–212.
5. Kiowski, W., Lüscher, T.F., Linder, L. and Bühler, F.R. (1991) Endothelin-1 induced vasoconstriction in man: Reversal by calcium channelblockade but not by nitrovasodilators or endothelium derived relaxing factor. Circulation, 83 469–475.
6. Wright, C.E. and Frozard, J.R. (1988) Regional vasodilation is a prominent feature of the hemodynamic response to endothelin in spontaneously hypertensive rats. European Journal of Pharmacology, 155 201–203.
7. Lüscher, T.F., Yang, Z., Tschudi, M., von Segesser, L., Stulz, P. and Boulanger, C.M. (1990) Interactions between endothelin and endothelium-derived relaxing factor in human arteries and veins. Circulatory Research, 66 (4) 1088–1094.
8. Leadly, R.J., Zhy, J.L. and Goetz, K.L. (1991) Effects of endothelin-1 and sarafotoxin S6b on regional hemodynamics in the conscious dog. Americal Journal of Physiology, 260 R 1210–1217.
9. Warner, T.D., Mitchell, J.A., de Nucci, G. and Vane, J.R. (1989) Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit. Journal of Cardiovascular Pharmacology, 13 (suppl 15) 85–88.
10. Boulanger, C.M. and Lüscher, T.F. (1990) Release of endothelin from the porcine aorta: Inhibition by endothelium derived nitric oxide. Journal of Clinical Investigation, 85 587–590
11. Pernow, J., Hemsen, A., Hallén, A. and Lundberg, J.M. (1990) Release of endothelin-like immunoreactivity in relation to neuropeptide Y and catecholamines during endotoxin shock and asphyxia in the pig. Acta Physiologica Scandinavica, 140 311–322.
12. Pittet, J.F., Morel, D.R., Hemsen, B.S., Gunning, K., Lacroix, J.S., Suter, P.M. and Lundberg, J.M. (1991) Elevated plasma endothelin-1 concentrations are associated with severity of illness in patients with sepsis. Annals of Surgery, 213(3) 261–264.
13. Lerman, A., Click, R.L., Narr, B.J., Wiesner, R.H., Krom, R.A.F., Textor, S.C. and Burnett, J.C. Jr. (1991) Elevation of plasma endothelin associated with systemic hypertension following orthotopic liver transplantation. Transplantation, 51(3)646–650.
14. Asbert, M., Gines A., Gines, P., Jimenez, W., Claria, J., Salo, J., Arroyo, V., Rivera, F. and Rodes, J. (1993) Circulating levels of endothelin in cirrhosis. Gastroenterology, 104(5) 1485–1491.
15. Kurihara, T., Akimoto, M., Kurokawa, K., Ishiguro, H., Niimi, A., Maeda, A. and Sigemoto, M. et al. (1992) Relationship between endothelin and thromboxane A2 in the rat liver microcirculation. Life Sciences, 51(26) PL281–285.
16. Gandhi, C.R., Harvey, S.A. and Olson, M.S. (1993) Hepatic effects of endothelin: metabolism of endothelin-1 by liver-derived cells. Archives of Biochemistry and Biophysics, 305(1) 38–46.
17. Roden, M., Vierhapper, H., Liener, K. and Waldhäusl, W. (1992) Endothelin-1 stimulated glucose production in the isolated perfused rat liver. Metabolism, 41 290–295.
18. Shiba, R., Yanagisawa, M., Miyauchi, T., Ishii, Y., Kimura, S., Uchiyama, Y., Masaki, T. and Goto, K. (1989) Elimination of intravenously injected endothelin-1 from the circulation of the rat. Journal of Cardivascular Pharmacology, 13 (suppl 5) 98–101.
19. Wagner, O.F., Vierhapper, H., Gasic, S., Nowotny, P. and Waldhäusl, W. (1992) Regional effects and clearance of endothelin-1 across pulmonary and splanchnic circulation. European Journal of Clinical Investigation, 22 277–282.
20. Pohl, U. and Busse, R. (1989) Differential vascular sensitivity to luminally and adventitially applied endothelin-1. Journal of Cardivascular Pharmacology, 13 (suppl 5) 188–190.
21. Greenway, C.V. and Lautt, W.W. (1989) Hepatic circulation. In Handbook of physiology, The Gastrointestinal System; edited by J.D. Wood vol. 1(2), pp. 1519–1564. New York: Oxford University Press
22. Lautt, W.W. (1985) Mechanism and role of intrinsic regulation of hepatic arterial blood flow: the hepatic artery buffer response. American Journal of Physiology, 249 G549–G556.
23. Pernow, J., Hemsen, A. and Lundberg, J.M. (1989) Tissue specific distribution, clearence and vascular effects of endothelin in the pig. Biochemical and Biophysical Research Communications, 161 (2) 647–653