Expression of Hel-N1 and Hel-N2 in small-cell lung carcinoma

Annals of Neurology

Volumn 39, Issue 5, 1996, Pages 679-681

  King, Peter H ^a,c   Dropcho, Edward J ^b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b INDIANA UNIVERSITY MEDICAL CENTER   (United States)

^c 1235 Jefferson Tower ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; RNA BINDING PROTEIN;

ANTIGEN EXPRESSION; ARTICLE; HUMAN; LUNG SMALL CELL CANCER; MESSENGER RNA SYNTHESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BASE SEQUENCE; CARCINOMA, SMALL CELL; DNA PRIMERS; GENE EXPRESSION REGULATION, NEOPLASTIC; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; HUMANS; ISOMERISM; LEUKEMIA, ERYTHROBLASTIC, ACUTE; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; POLYMERASE CHAIN REACTION; RNA-BINDING PROTEINS; TUMOR CELLS, CULTURED;

EID: 0029932904     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.410390520     Document Type: Article

References (10)

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2. Szabo A, Dalmau J, Manley G, et al. HuD, a paraneoplastic encephalomyelitis antigen, contains RNA binding domains and is homologous to elav and sex-lethal. Cell 1991;67:325-333
3. Dropcho EJ. Autoimmune central nervous system paraneoplastic disorders: mechanisms, diagnosis, and therapeutic options. Ann Neurol 1995;37(Suppl 1):S102-S113
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6. Manley GT, Smitt PS, Dalmau J, et al. Hu antigens: reactivity with Hu antibodies, tumor expression, and major immunogenic sites. Ann Neurol 1995;38:102-110
7. Dropcho EJ, King PH. Autoantibodies against the Hel-N1 RNA-binding protein among patients with lung carcinoma: an association with type I anti-neuronol nuclear antibodies. Ann Neurol 1994;36:200-205
8. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159
9. King PH. Hel-N2: a novel isoform of Hel-N1 which is conserved in rat neural tissue and produced in early embryogenesis. Gene 1994;151:261-265
10. Liu J, Dalmau J, Szabo A, et al. Paraneoplastic encephalomyelitis antigens bind to the AU-rich elements of mRNA. Neurology 1995;45:544-550