Irreversible inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from yeast by F-244 and (RS)-β-butyrolactone

Canadian Journal of Chemistry

Volumn 74, Issue 1, 1996, Pages 24-27

  Bell, Karen ^a   Saepudin, Endang ^a   Harrison, Paul ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

butyrolactone; F 244; HMG CoA synthase; inhibitor; irreversible

Indexed keywords

12 HYDROXY 13 HYDROXYMETHYL 3,5,7 TRIMETHYLTETRADECA 2,4 DIENEDIOIC ACID 12,14 LACTONE; BETA BUTYROLACTONE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ENZYME BINDING; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; LIVER; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; YEAST;

EID: 0029932818     PISSN: 00084042     EISSN: None     Source Type: Journal    
DOI: 10.1139/v96-002     Document Type: Article

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