Histamine-induced skin reactions using iontophoresis and H1-blockade

Inflammation Research

Volumn 45, Issue SUPPL. 1, 1996, Pages

  Van Neste, D ^b   Leroy, D T ^a   De Brouwer, B ^b   Rihoux, J P ^a  

^a UCB PHARMA   (Belgium)

^b Belgian Skin Study Center   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CETIRIZINE; HISTAMINE; HISTAMINE H1 RECEPTOR;

ADULT; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; HUMAN EXPERIMENT; IONTOPHORESIS; MALE; NORMAL HUMAN; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL; SENSORY NERVE; SKIN BLOOD FLOW; SKIN MANIFESTATION; SKIN TEST; URTICARIA;

EID: 0029932560     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03354083     Document Type: Conference Paper

References (7)

1. Thysman S, Van Neste D, Préat V. Noninvasive investigation of human skin after in vivo iontophoresis. Skin Pharmacol. 1995;8:229-36.
2. Thysman S, Jadoul A, Leroy T, Van Neste D, Préat V. Laser doppler evaluation of skin reaction in volunteers after histamine iontophoresis. J Controlled Release. In press.
3. Thysman S. Resorption transcutanée de médicaments par iontrophorèse. Thèse présentée en vue de l'obtention du grade de Docteur en Sciences Pharmaceutiques. Université Catholique de Louvain. Ecole de Pharmacie. Unité de Pharmacie Galénique 1993.
4. Poulsen LK, Bindslev-Jensen C, Rihoux JP. Quantitative determination of skin reactivity by two semiautomatic devices for skin prick test area measurements. Agents Actions 1994;41: C134-5.
5. Hills M, Armitage P. The two-period cross-over clinical trial. Br J Clin Pharmac 1979;8:7-20.
6. Rihoux J-P, Van Neste DJJ. Quantitative time course study of the skin response to histamine and the effect of H1 blockers. Dermatologica 1989;179:129-34.
7. Van Neste D, Coussement C, Ghys L, Rihoux J-P. Agonist-antagonist interactions in the skin: comparison of effects of loratadine and cetirizin on skin vascular responses to prick tests with histamine and substance P. J Dermal Sci 1992;4:172-9.