Structure-activity relationships of non-peptide vasopressin V1a antagonists: 1-(1-multi-substituted benzoyl 4-piperidyl)-3,4-dihydro-2(1H)-quinolinones

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 4, 1996, Pages 725-733

  Kondo, Kazumi ^a   Ogawa, Hidenori ^a   Nakaya, Kenji ^a   Tominaga, Michiaki ^a   Yabuuchi, Youichi ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Non peptide; Structure activity relationships; Synthesis; Vasopressin V1a antagonist

Indexed keywords

1 (1 BENZOYL 4 PIPERIDYL) 3,4 DIHYDRO 2(1H) QUINOLINONE; 1 [1 [4 (3 ACETAMIDOPROPOXY)BENZOYL] 4 PIPERIDYL] 1,2,3,4 TETRAHYDRO 2 QUINOLINONE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; VASOPRESSIN ANTAGONIST; VASOPRESSIN V1 RECEPTOR;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE; DRUG STRUCTURE; DRUG SYNTHESIS; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL MEMBRANE; HYDROGEN BONDING; LIVER; PIPERIDINES; QUINOLONES; RATS; RECEPTORS, VASOPRESSIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029932331     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.725     Document Type: Article

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