Transdermal prodrug concepts: Permeation of buprenorphine and its alkyl esters through hairless mouse skin and influence of vehicles

Biological and Pharmaceutical Bulletin

Volumn 19, Issue 2, 1996, Pages 263-267

  Imoto, Hirofumi ^a,b   Zhou, ZiQi ^a   Stinchcomb, Audra L ^a   Flynn, Gordon L ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

alkyl ester prodrug; buprenorphine; hairless mouse skin; transdermal drug delivery; vehicle effect

Indexed keywords

BUPRENORPHINE; BUPRENORPHINE ACETATE; BUPRENORPHINE BUTYRATE; BUPRENORPHINE ISOBUTYRATE; DRUG VEHICLE; PRODRUG; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DRUG DIFFUSION; DRUG FORMULATION; DRUG METABOLISM; DRUG PENETRATION; DRUG SOLUBILITY; HYDROPHILICITY; MALE; MOUSE; NONHUMAN; NUDE MOUSE; SKIN PERMEABILITY; TRANSDERMAL DRUG ADMINISTRATION;

EID: 0029932231     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.19.263     Document Type: Article

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