Genomic Structure of a Y-Specific Ribonucleic Acid Binding Motif-Containing Gene: A Putative Candidate for a Subset of Male Infertility

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 6, 1996, Pages 2159-2164

  Najmabadi, Hossein ^a   Chai, Ningning ^b   Kapali, Ananthalakshmi ^a   Subbarao, Makam N ^a   Bhasin, Dimple ^a   Woodhouse, Emma ^a   Yen, Pauline ^a   Bhasin, Shalender ^a  

^a CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^b HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA;

ARTICLE; CHROMOSOME YQ; GENE DELETION; GENE ISOLATION; GENE STRUCTURE; HUMAN; HUMAN CELL; MALE INFERTILITY; POINT MUTATION; PRIORITY JOURNAL; RNA BINDING; SEQUENCE HOMOLOGY; SINGLE STRAND CONFORMATION POLYMORPHISM;

BASE SEQUENCE; DNA; EXONS; GENE EXPRESSION; GENES; GENOME; HUMANS; INFERTILITY, MALE; INTRONS; MALE; MOLECULAR PROBES; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RNA-BINDING PROTEINS; TESTIS; TRANSCRIPTION, GENETIC; Y CHROMOSOME;

EID: 0029931261     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.81.6.8964845     Document Type: Article

References (41)

1. Bhasin S, DeKretser DM, Baker HWG. 1994 Pathophysiology and natural history of male factor infertility. J Clin Endocrinol Metab. 79:1525-1529.
2. Baker HWG, Burger HG, deKretser DM, Hudson B. 1986 Relative incidence of etiologic disorders in male infertility. In: Santen RJ, Swerdlotf RS, eds. Male reproductive dysfunction: diagnosis and management of hypogonadism, infertility, and impotence. New York: Marcel Dekker; 342-372.
3. DeKretser DM, Burger HG, Fortune D, et al. 1972 Hormonal, histological and chromosomal studies in adult males with testicular disorders. J Clin Endocrinol Metab. 35:392-340.
4. Dubin L, Amelar RD. 1971 Etiologic factors in 1294 consecutive cases of male fertility. Fertil Steril. 22:469-474.
5. Howards SS. 1995 Treatment of infertility. N Engl J Med. 332:312-317.
6. Vergnaud E, Page DC, Simmler MC, et al. 1986 Deletion map of the human Y chromosome based on DNA hybridization. Am J Hum Genet. 38:109-124.
7. Tiepolo L, Zuffardi O. 1976 Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human Y chromosome long arm. Hum Genet. 34:119-124.
8. Anderson M, Page DC, Pettay D, et al. 1988 Ytosome translocations and mosaicism in the etiology of 45, X maleness: assignment of fertility factor to distal Yq11. Hum Genet. 79:2-7.
9. Anderson M, Page DC, Brown LG, Elving K, de la Chapelle A. 1988 Characterization of a (Y;4) translocation of DNA hybridization. Hum Genet. 78: 377-381.
10. Cantu JM, Diaz M, Moller M, et al. 1985 Azoospermia and duplication 3qter as distinct consequences of a familial t(X;3)(q263.2). Am J Med Genet. 20:677-684.
11. Disteche CM, Brown L, Saal H, et al. 1986 Molecular detection of a translocation (Y;15)in a 45,X male. Hum Genet. 74:372-377.
12. Smith A, et al. 1979 An infertile male with balanced Y;19 translocation. Review of Ytosome translocation. Ann Genet. 22:189-194.
13. Maeda T, Ohno M, Ishibashi A, Samefjima M, Sasaki K. 1976 Ring Y chromosome: 45,X/46,X, r(Y) chromosome mosaicism in a phenotypically normal male with azoospermia. Hum Genet. 34:99-102.
14. Guichaoua MR, Speed RM, Luciani JM, Delafontaine D, Chandley AC. 1992 Infertility in human males with autosomal translocations. II. Meiotic studies in three reciprocal rearrangements, one showing tertiary monosomyin a 45-chromosome individual and his father. Cytogenet Cell Genet. 60:96-101.
15. Kotecki M, Jaruzelska J, Skowronska M, Fichna P. 1991 Deletion mapping of interval 6 of the human Y chromosome. Hum Genet. 87:234-236.
16. + azoospermic male. Clin Genet. 28:80-83.
17. Neu RL, Matthew MS, Barlow J, Gardner LI. 1973 A 46, Xyq-male with azoospermia. Fertil Steril. 24:811-813.
18. Chandley AC, Cooke HJ. 1994 Human male fertility Y-linked genes and spermatogenesis. Hum Mol Genet. 3:1449-1452.
19. Vogt P, Chandley AC, Hargreave TB, Keil R, Ma K, Sharkey A. 1992 Microdeletions in interval 6 of the Y chromosome of male with idiopathic sterility point to disruption of AZF, a human spermatogenesis gene. Hum Genet. 89:491-496.
20. Marachio P, Tupler R, Daintle E, Cortinovis M, Tiepolo L. 1994 Molecular analysis of human Y:1 translocation in an azoospermic male. Cytogen Cell Genet. 65:256-262.
21. Camurri L, Novelli G, Gennarelli M, Cantarelli M, Dallapicollo B. 1943 Yq deletions and AZF locus: molecular analysis in two fetuses with non-familial homozygous Yq rearrangements. Genet Counseling. 4:223.
22. Sasagawa I, Nakada T, Adachi Y, et al. 1993 Y: autosome translocation associated with azoospermia. Scand J Urol Nephrol. 27:285.
23. Burgoyne PS. 1987 The role of the mammalian Y chromosome in spermatogenesis. Development. 101(Suppl):133-141.
24. Ma K, Sharkey A, Kirsh S, et al. 1992 Towards the molecular localization of the AZF locus: mapping of microdeletions in azoospermic men within 14 subintervals of interval 6 of the human Y chromosome. Hum Mol Genet. 1:24-33.
25. Nagafuchi S, Namiki M, Nakahor Y, Kondoh N, Okuyama A, Naagome Y. 1993 A minute deletion of the Y chromosome in men with azoospermia. J Urol. 150:1155-1157.
26. Henegariu O, Hirschmann F, Killian K, et al. 1994 Rapid screening of the Y chromosome in idiopathic sterile men, diagnostic for deletions in AZF, a genetic Y factor expressed during spermatogenesis. Andrologia 26:97-106.
27. Ma K, Inglis JD, Sharkey A, et al. 1993 A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis. Cell. 75:1287-1295.
28. Kim YJ, Baker BS. 1993 Isolation of RRM-type RNA-binding protein genes and the analysis of their relatedness by using a numerical approach. J Am Soc Microbiol. 13:174-183.
29. Jones MH, Khwaja OSA, Briggs H, et al. 1994 A set of ninety-seven overlapping yeast artificial chromosome clones spanning the human Y chromosome Genomics. 24:266-275.
30. Sambrook J, Fritsch EF, Maniatis T. 1989 Molecular cloning - a laboratory manual, 2nd ed. Cold Spring Harbor: Cold Spring Harbor Laboratory.
31. Foote S, Vollrath D, Hilton A, Page DC. 1992 The human Y chromosome overlapping DNA clones spanning the euchromatic region. Science. 258:60-66.
32. Vogt P, Hennig W, Siegmund I. 1982 Identification of cloned Y chromosome DNA sequences from a lampbrush loop of Drosophila hydei. Proc Natl Acad Sci USA. 79:5132-5136.
33. Brousseau GE. 1960 Genetic analysis of the male fertility factor on the Y chromosome of Drosophila melanogaster. Genetics. 44:257-274.
34. Vogt P, Keil R, Kohler M, Lengauer C, Lewe D, Lewe G. 1941 Selection of DNA sequences from interval 6 of the human Y chromosome with homology to a Y chromosomal fertility gene sequence of Drosophila hydei. Hum Genet. 86:341-349.
35. Najmabadi H, Huang V, Yen P, et al. Substantial prevalence of microdeletions of the Y chromosome in infertile men with idiopathic azoospermia and oligozoospermia detected using a sequence tagged site (STS) based mapping strategy. J Clin Endocrinol Metab. 81:1347-1352.
36. Soulard M, Della Valle V, Siomi MC, et al. 1993 hnRNP G: sequence and characterization of a glycosylated RNA-binding protein. Nucleic Acids Res. 21:4210-4217.
37. Amrein H, Gorman M, Nothiger R. 1988 The sex determining gene tra-2 of Drosophila encodes a putative RNA binding protein. Cell. 55:1025-1035.
38. Baker BS. 1989 Sex in flies: the splice of life. Nature. 340:521-524.
39. Bell LR, Maine EM, Schedl P, Cline TW. 1988 Sex-lethal, a Drosophila sex determination switch gene, exhibits sex-specific RNA splicing and sequence similarity to RNA binding proteins. Cell. 55:1037-1046.
40. Lilford R, Jones MA, Bishop DT, Thornton J, Mueller R. 1994 Case-control study of whether subfertility in men is familial. Br Med J 304:570-573.
41. Reijo R, Lee TY, Salo P, et al. 1995 Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. Nature Genet. 10:383-392.