-
1
-
-
15844398242
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-
note
-
2O).
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-
-
-
2
-
-
0028297726
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-
Hatanaka, H.; Nakagawa, Y. Int. Rad. Oncol. 1994, 28, 1061-1066. Hawthorne, M. F. Angew. Chem., Int. Ed. Engl. 1993, 32, 950-984. Slatkin, D. N. Brain 1991, 114, 1609-1629. Fairchild, R. G.; Wheeler, F.; Slatkin, D. N.; Coderre, J.; Micca. P.; Laster, B.; Kahl, S. B.; Som, P.; Fand, I. Strahlenther. Onkol. 1989, 165, 343-347.
-
(1994)
Int. Rad. Oncol.
, vol.28
, pp. 1061-1066
-
-
Hatanaka, H.1
Nakagawa, Y.2
-
3
-
-
33745945620
-
-
Hatanaka, H.; Nakagawa, Y. Int. Rad. Oncol. 1994, 28, 1061-1066. Hawthorne, M. F. Angew. Chem., Int. Ed. Engl. 1993, 32, 950-984. Slatkin, D. N. Brain 1991, 114, 1609-1629. Fairchild, R. G.; Wheeler, F.; Slatkin, D. N.; Coderre, J.; Micca. P.; Laster, B.; Kahl, S. B.; Som, P.; Fand, I. Strahlenther. Onkol. 1989, 165, 343-347.
-
(1993)
Angew. Chem., Int. Ed. Engl.
, vol.32
, pp. 950-984
-
-
Hawthorne, M.F.1
-
4
-
-
0025895856
-
-
Hatanaka, H.; Nakagawa, Y. Int. Rad. Oncol. 1994, 28, 1061-1066. Hawthorne, M. F. Angew. Chem., Int. Ed. Engl. 1993, 32, 950-984. Slatkin, D. N. Brain 1991, 114, 1609-1629. Fairchild, R. G.; Wheeler, F.; Slatkin, D. N.; Coderre, J.; Micca. P.; Laster, B.; Kahl, S. B.; Som, P.; Fand, I. Strahlenther. Onkol. 1989, 165, 343-347.
-
(1991)
Brain
, vol.114
, pp. 1609-1629
-
-
Slatkin, D.N.1
-
5
-
-
0024503724
-
-
Hatanaka, H.; Nakagawa, Y. Int. Rad. Oncol. 1994, 28, 1061-1066. Hawthorne, M. F. Angew. Chem., Int. Ed. Engl. 1993, 32, 950-984. Slatkin, D. N. Brain 1991, 114, 1609-1629. Fairchild, R. G.; Wheeler, F.; Slatkin, D. N.; Coderre, J.; Micca. P.; Laster, B.; Kahl, S. B.; Som, P.; Fand, I. Strahlenther. Onkol. 1989, 165, 343-347.
-
(1989)
Strahlenther. Onkol.
, vol.165
, pp. 343-347
-
-
Fairchild, R.G.1
Wheeler, F.2
Slatkin, D.N.3
Coderre, J.4
Micca, P.5
Laster, B.6
Kahl, S.B.7
Som, P.8
Fand, I.9
-
6
-
-
84986384704
-
-
Leukart, O.; Caviezel, M.; Eberle, A.; Escher, E.; Tun-Kyi, A.; Schwyzer, R. Helv. Chim. Acta 1976, 59, 2184-2187. Fauchere, J.-L.; Leukart, O.; Eberle, A.; Schwyzer, R. Helv. Chim. Acta 1979, 62, 1382-1395.
-
(1976)
Helv. Chim. Acta
, vol.59
, pp. 2184-2187
-
-
Leukart, O.1
Caviezel, M.2
Eberle, A.3
Escher, E.4
Tun-Kyi, A.5
Schwyzer, R.6
-
7
-
-
0018744871
-
-
Leukart, O.; Caviezel, M.; Eberle, A.; Escher, E.; Tun-Kyi, A.; Schwyzer, R. Helv. Chim. Acta 1976, 59, 2184-2187. Fauchere, J.-L.; Leukart, O.; Eberle, A.; Schwyzer, R. Helv. Chim. Acta 1979, 62, 1382-1395.
-
(1979)
Helv. Chim. Acta
, vol.62
, pp. 1382-1395
-
-
Fauchere, J.-L.1
Leukart, O.2
Eberle, A.3
Schwyzer, R.4
-
8
-
-
15844390236
-
-
Kabalka, G. W., Ed.; Royal Society of Chemistry: Cambridge, U.K.
-
Sjöberg, S.; Carlsson, J.; Lindtrom, P.; Malmquist, J. Current Topics In The Chemistry of Boron; Kabalka, G. W., Ed.; Royal Society of Chemistry: Cambridge, U.K. 1994; pp 172-176.
-
(1994)
Current Topics in the Chemistry of Boron
, pp. 172-176
-
-
Sjöberg, S.1
Carlsson, J.2
Lindtrom, P.3
Malmquist, J.4
-
10
-
-
0028888232
-
-
Karnbrock, W.; Musiol, H.-J.; Moroder, L. Tetrahedron 1995, 51, 1187-1196.
-
(1995)
Tetrahedron
, vol.51
, pp. 1187-1196
-
-
Karnbrock, W.1
Musiol, H.-J.2
Moroder, L.3
-
11
-
-
0000242199
-
-
Arnold, L. D.; Drover, J. C. G.; Vederas, J. C. J. Am. Chem. Soc. 1987, 109, 4649-4659.
-
(1987)
J. Am. Chem. Soc.
, vol.109
, pp. 4649-4659
-
-
Arnold, L.D.1
Drover, J.C.G.2
Vederas, J.C.3
-
12
-
-
15844427950
-
-
Zakharkin, L. I.; Kovredov, A. I.; Shaugumbekova, Z. S.; Vinogradova, L. E.; Leites, L. A. Zh. Obshch. Khim. 1981, 51, 1582-1586.
-
(1981)
Zh. Obshch. Khim.
, vol.51
, pp. 1582-1586
-
-
Zakharkin, L.I.1
Kovredov, A.I.2
Shaugumbekova, Z.S.3
Vinogradova, L.E.4
Leites, L.A.5
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13
-
-
15844368029
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-
note
-
For many applications, the difference between incorporating a meta-carborane cage into the amino acid or incorporating an o-carborane functionality was not important.
-
-
-
-
15
-
-
0025324609
-
-
Evans, D. A.; Britton, T. C.; Ellman, J. A.; Dorow, R. L. J. Am. Chem. Soc. 1990, 112, 4011-4030.
-
(1990)
J. Am. Chem. Soc.
, vol.112
, pp. 4011-4030
-
-
Evans, D.A.1
Britton, T.C.2
Ellman, J.A.3
Dorow, R.L.4
-
17
-
-
0000995951
-
-
Kabalka, W. G.; Shoup, T. M.; Goudgaon, N. M. J. Org. Chem. 1989, 54, 5930-5933.
-
(1989)
J. Org. Chem.
, vol.54
, pp. 5930-5933
-
-
Kabalka, W.G.1
Shoup, T.M.2
Goudgaon, N.M.3
-
18
-
-
0008902080
-
-
Kabalka, G. W., Ed.; Royal Society of Chemistry: Cambridge, U.K.
-
Kahl, S. B.; Radel, P. A. Current Topics In The Chemistry of Boron; Kabalka, G. W., Ed.; Royal Society of Chemistry: Cambridge, U.K. 1994; pp 155-160.
-
(1994)
Current Topics in the Chemistry of Boron
, pp. 155-160
-
-
Kahl, S.B.1
Radel, P.A.2
-
20
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0342754732
-
-
A one-pot sequence to obtain the carboxylic acid directly from allylcarborane by oxidation of the intermediate organoborane according to the method of Perisamy (Perisamy, M.; Narayana, C.; Anitha, N. Indian J. Chem. 1986, 25B, 844-846) was not successful.
-
(1986)
Indian J. Chem.
, vol.25 B
, pp. 844-846
-
-
Perisamy, M.1
Narayana, C.2
Anitha, N.3
-
23
-
-
15844430582
-
-
note
-
2O, giving final solvent proportions of 1:2 (Et2O:benzene), to achieve a sufficiently polar mixture to permit reaction. The crude sublimed silyl-protected o-carborane was chromatographed on silica with hexane instead of final purification by distillation. Use of material purified in this manner, in the subsequent modified alkylation with allyl bromide, permitted 91% of the product 1-silyl 2-allyl o-carborane to be isolated, after chromatographic purification on silica gel.
-
-
-
-
24
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0001621590
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-
Tomita, H.; Luu, H.; Onak, T. Inorg. Chem. 1991, 30, 812-815.
-
(1991)
Inorg. Chem.
, vol.30
, pp. 812-815
-
-
Tomita, H.1
Luu, H.2
Onak, T.3
-
25
-
-
33748468588
-
-
Evans, D. A.; Urpi, F.; Somers, T. C.; Clark, J. S.; Bilodeau, M. T. J. Am. Chem. Soc. 1990, 112, 8215-8216.
-
(1990)
J. Am. Chem. Soc.
, vol.112
, pp. 8215-8216
-
-
Evans, D.A.1
Urpi, F.2
Somers, T.C.3
Clark, J.S.4
Bilodeau, M.T.5
-
27
-
-
15844385262
-
-
note
-
This improved overall yield differs from that in Scheme 4; it is the result of carrying crude bromo imide on to the azido imide intermediate. Scheme 4 reports stepwise yields, after chromatography. The bromo imide is susceptible to decomposition on silica gel.
-
-
-
-
28
-
-
0000687379
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-
Evans, D. A.; Ellman, J. A.; Dorow, R. L. Tetrahedron Lett. 1987, 28, 1123-1126.
-
(1987)
Tetrahedron Lett.
, vol.28
, pp. 1123-1126
-
-
Evans, D.A.1
Ellman, J.A.2
Dorow, R.L.3
-
29
-
-
0003998388
-
-
CRC Press: Cleveland, OH
-
The rotation had been reported using water as the solvent. Attempts to dissolve the stated amount of amino acid were not successful. Phenylalanine itself, a less hydrophobic amino acid, is only soluble to the extent of 2.96 g/100 mL of water. (Handbook of Chemistry and Physics, 55th Ed.; Weast, R. C., Ed.; CRC Press: Cleveland, OH, 1974; C-743). Attempts to improve the solubility by adding hydrochloric acid caused a change of sign of the rotation. This is also not unheard of for hydrophobic amino acids. Leucine is an example (Ibid., p C-742).
-
(1974)
Handbook of Chemistry and Physics, 55th Ed.
-
-
Weast, R.C.1
-
30
-
-
0003998388
-
-
The rotation had been reported using water as the solvent. Attempts to dissolve the stated amount of amino acid were not successful. Phenylalanine itself, a less hydrophobic amino acid, is only soluble to the extent of 2.96 g/100 mL of water. (Handbook of Chemistry and Physics, 55th Ed.; Weast, R. C., Ed.; CRC Press: Cleveland, OH, 1974; C-743). Attempts to improve the solubility by adding hydrochloric acid caused a change of sign of the rotation. This is also not unheard of for hydrophobic amino acids. Leucine is an example (Ibid., p C-742).
-
Handbook of Chemistry and Physics, 55th Ed.
-
-
-
31
-
-
49049124890
-
-
Vaultier, M.; Knouzi, N.; Carie, R. Tetrahedron Lett. 1983, 24, 763-764.
-
(1983)
Tetrahedron Lett.
, vol.24
, pp. 763-764
-
-
Vaultier, M.1
Knouzi, N.2
Carie, R.3
-
32
-
-
0010640653
-
-
Dale, J. A.; Dull, D. L.; Mosher, H. S. J. Org. Chem. 1969, 34, 2543-2549.
-
(1969)
J. Org. Chem.
, vol.34
, pp. 2543-2549
-
-
Dale, J.A.1
Dull, D.L.2
Mosher, H.S.3
-
33
-
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15844393073
-
-
note
-
Several other columns and conditions were evaluated for their utility; neither Nucleosil-2 nor Chiralcel OT columns permitted separation of the isomers.
-
-
-
-
34
-
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0000959546
-
-
Wiley: New York
-
Meinwald, J.; Crandall, J.; Hymans, E. Organic Synthesis; Wiley: New York, 1973; Collect. Vol. 5, pp 866-868.
-
(1973)
Organic Synthesis
, vol.5 COLLECT. VOL.
, pp. 866-868
-
-
Meinwald, J.1
Crandall, J.2
Hymans, E.3
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