The width of the minor groove affects the binding of the bisquaternary heterocycle SN-6999 to duplex DNA

Nucleic Acids Research

Volumn 24, Issue 7, 1996, Pages 1287-1293

  Rydzewski, Jan M ^a   Leupin, Werner ^b,c   Chazin, Walter ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; HETEROCYCLIC COMPOUND; PYRIDINIUM DERIVATIVE;

ARTICLE; DNA STRUCTURE; DRUG DNA BINDING; LIGAND BINDING; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTINEOPLASTIC AGENTS; BASE SEQUENCE; BINDING SITES; DNA; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; QUINOLINIUM COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029930932     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/24.7.1287     Document Type: Article

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