Endothelin-induced changes of second messengers in cultured human ciliary muscle cells

Investigative Ophthalmology and Visual Science

Volumn 37, Issue 6, 1996, Pages 1058-1066

  Matsumoto, Shun ^a,c   Yorio, Thomas ^a   Magnino, Peggy E ^b   Desantis, Louis ^b   Pang, Iok Hou ^a,b  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^b ALCON RESEARCH LTD   (United States)

^c TOKYO TEISHIN HOSPITAL   (Japan)

Author keywords

ciliary muscle cell; cyclic adenosine monophosphate; endothelin; intracellular calcium; phospholipase C

Indexed keywords

ADENYLATE CYCLASE; CALCIUM ION; CYCLIC AMP; ENDOTHELIN; ENDOTHELIN A RECEPTOR; PHOSPHOLIPASE C; PROSTAGLANDIN E2;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CILIARY MUSCLE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SECOND MESSENGER;

ADENYLATE CYCLASE; CALCIUM; CELLS, CULTURED; CILIARY BODY; CYCLIC AMP; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; ENDOTHELINS; FLUORESCENT DYES; FURA-2; HUMANS; INDOMETHACIN; INOSITOL PHOSPHATES; MUSCLE, SMOOTH; OLIGOPEPTIDES; PHOSPHOLIPASE C; RECEPTORS, ENDOTHELIN; SECOND MESSENGER SYSTEMS; VASOCONSTRICTOR AGENTS; VIPER VENOMS;

EID: 0029930660     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Yanagisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411-415.
2. Chakravarthy U, Douglas AJ, Bailie JR, McKibben B, Archer DB. Immunoreactive endothelin distribution in ocular tissues. Invest Ophthalmol Vis Sci. 1994; 35:2448-2454.
3. Eichhorn M, Lütjen-Drecoll E. Distribution of endothelin-like immunoreactivity in the human ciliary epithelium. Curr Eye Res. 1993; 12:753-757.
4. Lepple-Wienhues A, Becker M, Stahl F, et al. Endothelin-like immunoreactivity in the aqueous humour and in conditioned medium from cultured ciliary epithelial cells. Curr Eye Res. 1992; 11:1041-1046.
5. Granstam E, Wang L, Bill A. Effects of endothelins (ET-1, ET-2 and ET-3) in the rabbit eye: Role of prostaglandins. Eur J Pharmacol. 1991;194:217-223.
6. MacCumber MW, Jampel HD, Snyder SH. Ocular effects of the endothelins: Abundant peptides in the eye. Arch Ophthalmol. 1991; 109:705-709.
7. Azuma I. Progress in medical treatment for glaucoma. J Jpn Ophthalmol Soc. 1993;97:1353-1369.
8. Okada K, Sugiyama K, Haque SR, Taniguchi T, Kitazawa Y. Biphasic intraocular pressure response to intravitreal injection of endothelin-1. J Jpn Ophthalmol Soc. 1994; 98:935-941.
9. Lepple-Wienhues A, Stahl F, Willner U, Schaefer R, Wiederholt M. Endothelin-evoked contractions in bovine ciliary muscle and trabecular meshwork: Interaction with calcium, nifedipine and nickel. Curr Eye Res. 1991;10:983-989.
10. Kaufman P, Barany E. Loss of acute pilocarpine effect on outflow facility following surgical disinsertion and retrodisplacement of the ciliary muscle from the scleral spur in the cynomolgus monkey. Invest Ophthalmol. 1976; 15:793-807.
11. Erickson-Lamy K, Korbmacher C, Schuman J, Nathanson J. Effect of endothelin on outflow facility and accommodation in the monkey eye in vivo. Invest Ophthalmol Vis Sci. 1991;32:492-495.
12. Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi H. Cloning and expression of a cDNA encoding an endothelin receptor. Nature. 1990;348:730-732.
13. Sakurai T, Yanagisawa M, Takuwa Y, et al. Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature. 1990;348:732-735.
14. Rubanyi GM, Polokoff MA. Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathology. Pharmacol Rev. 1994;46:325-415.
15. c receptor) from Xenopus laevis dermal melanophores. J Biol Chem. 1993;268:19126-19133.
16. Tamm E, Flügel C, Baur A, Lütjen-Drecoll E. Cell cultures of human ciliary muscle: Growth, ultrastructural and immunocytochemical characteristics. Exp Eye Res. 1991;53:375-387.
17. Matsumoto S, Yorio T, DeSantis L, Pang I-H. Muscarinic effects on cellular functions in cultured human ciliary muscle cells. Invest Ophthalmol Vis Sci. 1994;35:3732-3738.
18. 2+ indicators with greatly improved fluorescence properties. J Biol Chem. 1985;260:3440-3450.
19. Pang I-H, Shade DL, Clark AF, Steely HT, DeSantis L. Preliminary characterization of a transformed cell strain derived from human trabecular meshwork. Curr Eye Res. 1994; 13:51-63.
20. William DL, Jones KL, Pettibone DJ, Lis EV, Clineschmidt BV. Sarafotoxin 6c; An agonist which distinguishes between endothelin receptor subtype. Biochem Biophys Res Commun. 1991;175:556-561.
21. A receptors. In: Schneider C, Eberle A, eds. Peptides 1992. New York: ESCOM Science Publishers; 1993:685-686.
22. Stahl F, Gebauer B, Lepple-Wienhues A, Langen-beck-Groh G, Berweck S, Wiederholt M. Characterization of acetylcholine- and endothelin-induced calcium entry in cultured human ciliary muscle cells. Pflugers Arch. 1992;422:105-111.
23. Abdel-Latif AA, Zhang Y. Species differences in the effects of endothelin-1 on myoinositol triphosphate accumulation, cyclic AMP formation and contraction of isolated iris sphincter of rabbit and other species, Invest Ophthalmol Vis Sa. 1991;32:2432-2438.
24. Osborne NN, Barnett NL. Endothelin-1 stimulates phosphatidylinositol hydrolysis in the iris/ciliary complex and is a potent constrictor of the sphincter muscle. Exp Eye Res. 1992;54:285-290.
25. Lepple-Wienhues A, Stahl F, Wunderling D, Wiederholt M. Effects of endothelin and calcium channel blockers on membrane voltage and intracellular calcium in cultured bovine trabecular meshwork cells. German J Ophthalmol. 1992; 1:159-163.
26. i in trabecular meshwork cells. Curr Eye Res. 1994; 13:197-202.
27. Pang I-H, Shade DL, Tamm E, DeSantis L. Single cell contraction assay for human ciliary muscle cells: effect of carbachol. Invest Ophthalmol Vis Res. 1993; 34:1876-1879.
28. Haque MSR, Taniguchi T, Sugiyama K, Okada K, Kitazawa Y. The ocular hypotensive effect of the ETB receptor selective agonsit, sarafotoxin S6c, in rabbits. Invest Ophthalmol Vis Sci. 1995;36:804-808.
29. El-Mowafy A, Abdel-Latif A. Characterization of iris sphincter smooth muscle endothelin receptor subtypes which are coupled to cyclic AMP formation and polyphosphoinositide hydrolysis. J Pharmacol Exp Ther. 1994;268:1341-1351.
30. Abdel-Latif AA, Zhang Y, Yousufzai SYK. Endothelin-1 stimulates the release of arachidonic acid and prostaglandins in rabbit iris sphincter smooth muscle: activation of phospholipase A2. Curr Eye Res. 1991;10:259-265.
31. Lograno MD, Reibaldi A. Receptor-responses in fresh human ciliary muscle. Br J Pharmacol. 1986;87:379-385.