Crystal structures and solution studies of oxime adducts of mitochondrial aspartate aminotransferase

European Journal of Biochemistry

Volumn 236, Issue 3, 1996, Pages 1025-1032

  Marković Housley, Zora ^a   Schirmer, Tilman ^a   Hohenester, Erhard ^a   Khomutov, Alex R ^b   Khomutov, Radii M ^c   Karpeisky, Marat Y ^c   Sandmeier, Erika ^d   Christen, Philipp ^d   Jansonius, Johan N ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b RUSSIAN ACADEMY OF SCIENCES   (Russian Federation)

^c ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

B6 enzyme; conformational change; crystal structure; ligand binding; oxime inhibitor

Indexed keywords

AMINO ACID DERIVATIVE; ASPARTATE AMINOTRANSFERASE; HYDROXYLAMINE;

ANIMAL TISSUE; ARTICLE; CHICKEN; CRYSTALLOGRAPHY; ENZYME BINDING; ENZYME STRUCTURE; HEART; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; GALLUS GALLUS;

EID: 0029930370     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.01025.x     Document Type: Article

References (36)

1. Birchmeier, W., Wilson, K. J. & Christen, P. (1973) J. Biol. Chem. 248, 1751-1759.
2. Collaborative Computing Project No.4 (1994) Acta Crystallogr. Sect. D Biol. Crystallogr. 50, 760-763.
3. Delbaere, L. T. J., Kallen, J., Marković-Housley, Z., Khomutov, A. R., Khomutov, R. M., Karpeisky, M. Ya. & Jansonius, J. N. (1989) Biochimie (Paris) 71, 449-459.
4. Edwards, J. O. & Pearson, R. G. (1962) J. Am. Chem. Soc. 84, 16-24.
5. Eichele, G., Karabelnik, D., Halonbrenner, R., Jansonius, J. N. & Christen, P. (1978) J. Biol. Chem. 253, 5239-5242.
6. Fasella, P., Giartosio, A. & Hammes, G. G. (1966) Biochemistry 5, 197-202.
7. Fasella, P. & Hammes, G. G. (1967) Biochemistry 6, 1798-1804.
8. Ford, G. C., Eichele, G. & Jansonius, J. N. (1980) Proc. Natl Acad. Sci. USA 77, 2559-2563.
9. Gehring, H. & Christen, P. (1975) Biochem. Biophys. Res. Commun. 63, 441-447.
10. Gehring, H., Christen, P., Eichele, G., Glor, M., Jansonius, J. N., Reimer, A.-S., Smit, J. D. G. & Thaller, C. (1977) J. Mol. Biol. 115, 97-101.
11. Gehring, H. & Christen, P. (1978) J. Biol. Chem. 253, 3158-3163.
12. Hammes, G. G. & Haslam, J. L. (1968) Biochemistry 7, 1519-1525.
13. Hohenester, E. & Jansonius, J. N. (1994) J. Mol. Biol. 236, 963-968.
14. Ivanov, V. I. & Karpeisky, M. Ya. (1969) Adv. Enzymol. 32, 21-53.
15. Jansonius, J. N., Eichele, G., Ford, G. C., Picot, D., Thaller, C. & Vincent, M. G. (1985) in Transaminases (Christen, P. & Metzler, D., eds) pp. 109-138, John Wiley & Sons, New York.
16. Jansonius, J. N. & Vincent, M. G. (1987) in Biological macromolecules and assemblies (Jurnak, F. A. & McPherson, A., eds) vol. 3, pp. 187-285, John Wiley & Sons, New York.
17. John, R. A., Charteris, A. & Fowler, L. Y. (1978) Biochem. J. 171, 771-779.
18. Karpeisky, M. Ya. & Ivanov, V. I. (1966) Nature 210, 493-496.
19. Karpeisky, M. Ya., Khomutov, R. H., Severin, E. S. & Breusov, Yu. N. (1963) in Chemical and biological aspects of pyridoxal catalysis (Snell, E. E., Fasella, P. M., Braunstein, A. E. & Rossi-Fanelli, A., eds) pp. 323-331, Pergamon Press, New York.
20. Khomutov, A. R., Karpeisky, M. Ya. & Severin, E. S. (1961) Biokhimia 26, 772-781.
21. Khomutov, R. M. Karpeisky, M. Ya. & Severin, E. S. (1963) in Chemical and biological aspects of pyridoxal catalysis (Snell, E. E., Fasella, P. M., Braunstein, A. E. & Rossi-Fanelli, A., eds) pp. 313-322, Pergamon Press, New York.
22. 6 (Korpela, T. & Christen, P., eds) pp. 317-320, Birkhäuser Verlag, Basel.
23. Kirsch, J. F., Eichele, G., Ford, G. C., Vincent, M. G., Jansonius, J. N., Gehring, H. & Christen, P. (1984) J. Mol. Biol. 174, 497-525.
24. Kosower, N. S., Kosower, E. M., Newton, G. L. & Ranney, H. M. (1979) Proc. Natl Acad. Sci. USA 76, 3382-3386.
25. Malashkevich, V. N., Toney, M. D. & Jansonius, J. N. (1993) Biochemistry 32, 13451-13462.
26. McPhalen, C. A., Vincent, M. G., Picot, D., Jansonius, J. N., Lesk, A. M. & Chothia, C. (1992a) J. Mol. Biol. 227, 197-213.
27. McPhalen, C. A., Vincent, M. G. & Jansonius, J. N. (1992b) J. Mol. Biol. 225, 495-517.
28. Messerschmidt, A. & Pflugrath, J. W. (1987) J. Appl. Crystallogr. 20, 306-315.
29. Pfister, K., Sandmeier, E., Berchtold, W. & Christen, P. (1985) J. Biol. Chem. 260, 11414-11421.
30. Picot, D. (1987) PhD thesis, University of Basel.
31. Picot, D., Sandmeier, E., Thaller, C., Vincent, M. G., Christen, P. & Jansonius, J. N. (1991) Eur. J. Biochem. 196, 329-431.
32. Raunio, R. P., Lindberg, R. K. & Jenkins, W. T. (1984) Arch. Biochem. Biophys. 233, 43-49.
33. Sandmeier, E. & Christen, P. (1980) J. Biol. Chem. 255, 10284-10289.
34. 6 catalysis (Evangelopoulos, A. E., ed.) part B, pp. 117-124, Liss, New York.
35. Thaller, C., Weaver, L. H., Eichele, G., Wilson, E., Karlsson, R. & Jansonius, J. N. (1981) J. Mol. Biol. 147, 465-469.
36. 6 catalysis (Evangelopoulos, A. E., ed.) part B, pp. 233-243, Liss, New York.