Acanthostral, a novel antineoplastic cis, cis, cis-germacranolide from Acanthospermum australe

Tetrahedron Letters

Volumn 37, Issue 9, 1996, Pages 1455-1456

  Matsunaga, Kimihiro ^a   Saitoh, Mika ^a   Ohizumi, Yasushi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACANTHOSTRAL; ADENOSINE TRIPHOSPHATASE; ANTINEOPLASTIC AGENT; CYCLIC AMP PHOSPHODIESTERASE; GERMACRANOLIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEUKEMIA L 1210; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHYTOCHEMISTRY; PLANT;

EID: 0029930192     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)82932-7     Document Type: Article

References (9)

1. The above-ground parts of A. australe were supplied by NKK Corporation, Tokyo, Japan.
2. F. Bohlmann, G. Schmeda-Hirschmann and J. Jakupovic, Planta Med., 1984, 50, 37.
3. S. Debenedetti, V. martino, P. Palacios and J. D. Coussio, J. Nat. Prod., 1987, 50, 325.
4. F. Bohlmann, J. Jakupovic, A. k. Dhar, R. M. King and H. Robinson, Phytochemistry, 1981, 20, 1081.
5. J. Jakupovic, V. Castro and F. Bholmann, Phytochemistry, 1987, 26, 2011.
6. C. Zdero, F. Bohlmann and R. Scott, Phytochemistry, 1987, 26, 1999.
7. W. Herz and P. S. Kalyanaraman, J. Org. Chem., 1975, 40, 3486.
8. 3): δ193(C-14), 175(C-1′), 169(C-12), 146(C-10), 143(C-9), 142(C-4), 135(C-11), 133(C-2), 123(C-13), 122(C-1), 121(C-5), 75.8(C-6), 68.9(C-8), 47.6(C-7), 34.0(C-2′), 33.7(C-3), 23.7(C-15), 11.5(C-3′).
9. Z. Samek, Tetrahedron Lett., 1970, 671.